Top 10 Novartis Jobs in California

Senior Scientist, Protein Production
Novartis —San Diego, CA
- $93,800 - $183,300 a year
- Full-time
- 5 years
- Bachelor of Science
- Bachelor's degree
- Health insurance
- 401(k) matching
Computational Medicinal Chemist
Novartis —San Diego, CA
- $126,000 - $257,400 a year
- Full-time
- 3 years
- Doctor of Philosophy
- Senior level
- Health insurance
- 401(k) matching
5d
Director Pathology
Novartis —San Diego, CA
- $204,400 - $379,600 a year
- Full-time
- Hybrid work
- Medicine
- Continuous improvement
- Doctor of Philosophy
- Health insurance
- 401(k) matching
Head, Oncology Drug Discovery – San Diego
Novartis —San Diego, CA
- $248,500 - $461,500 a year
- Full-time
- Doctoral degree
- 11+ years
- Mentoring
- Health insurance
- 401(k) matching
Data Science, Cheminformatics & AI: Lab-in-the-Loop Hit Finding
Novartis —San Diego, CA
- $138,600 - $257,400 a year
- Full-time
- Computer science
- SQL
- Doctor of Philosophy
- Health insurance
- 401(k) matching
Principal Scientist, Structural Biology
Novartis —San Diego, CA
- $108,500 - $222,300 a year
- Full-time
- 5 years
- Analysis skills
- Machine learning
- Health insurance
- 401(k) matching
Lab Automation & Logistics Delivery Lead
Novartis —San Diego, CA
- $152,600 - $283,400 a year
- Full-time
- Master's degree
- Doctor of Philosophy
- Agile
- Health insurance
- 401(k) matching
Manager, QA Method Validation
Novartis —Carlsbad, CA
- $114,100 - $211,900 a year
- Full-time
- Engineering
- 3 years
- Senior level
- Health insurance
- 401(k) matching
Production Support Supervisor, Nights
Novartis —Carlsbad, CA
- $85,400 - $158,600 a year
- 12 hour shift
- Mid-level
- 3 years
- Bachelor's degree
- Health insurance
- 401(k) matching
Innovation Postdoctoral Fellow, Data Science & AI Vision Foundation Models for Cellular Imaging in AI Drug Discovery
Novartis —San Diego, CA
- $87,000 a year
- Full-time
- Doctor of Philosophy
- US work authorization
- Communication skills
- Health insurance
- 401(k) matching

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novartis jobs near california

Senior Scientist, Protein Production

Novartis -
San Diego, CA

Apply Now

Job Details

Full-time
$93,800 - $183,300 a year

Benefits

Health insurance
401(k) matching

Qualifications

Cell line culture
Laboratory filtration
Protein analysis (analytical chemistry specialty)
Biochemical laboratory techniques
Chemical separation processes
Drug discovery
Cross-functional communication

Full Job Description

Summary

Come help us discover innovative therapeutic breakthroughs for patients! We are seeking a passionate, curious, and collaborative protein scientist to join our Protein Sciences group, an interdisciplinary team that has expertise in protein chemistry, enzymology, biophysics, NMR, X-ray crystallography, and electron microscopy.

As a Protein Scientist, you will focus primarily on the production of proteins to enable structure-guided drug discovery for multiple disease areas. Your responsibilities will include designing protein constructs, carrying out expression in various cell systems, developing methodologies for purification, and protein characterization using biophysical and structural techniques. You will closely collaborate with colleagues within our group and across disease areas to tackle challenging drug discovery projects, contributing to the advancement of early-stage drug development.

About the Role

Internal Job Title: Senior Scientist I/II

Location: onsite, San Diego, CA

About the role:

As a Protein Scientist, you will focus primarily on the production of proteins to enable structure-guided drug discovery for multiple disease areas. Your responsibilities will include designing protein constructs, carrying out expression in various cell systems, developing methodologies for purification, and protein characterization using biophysical and structural techniques. You will closely collaborate with colleagues within our group and across disease areas to tackle challenging drug discovery projects, contributing to the advancement of early-stage drug development.

Key Responsibilities:

Develop and execute protocols to generate high-quality protein reagents for small molecule screening, hit validation, and structural biology studies of protein-small molecule complexes.
Design protein constructs based on literature and AI-based structure prediction tools.
Express protein expression in mammalian and insect cell systems.
Purify protein purification using various chromatography techniques and FPLC equipment.
Collaborate with colleagues to characterize protein-protein and protein-ligand interactions using biophysical and structural biology techniques.
Apply critical thinking to troubleshoot experiments and design new approaches.
Maintain a high level of professional expertise through familiarity with scientific literature and accurate and detailed record keeping.
Work both independently and collaboratively as part of multidisciplinary teams.
Present and communicate results with protein science colleagues and project teams.

Essential Requirements:

BS/MS degree in biochemistry, life sciences, molecular biology or related field with at least 5+ years of relevant research laboratory experience.
Proven in-depth knowledge with hands-on experience in recombinant protein construct design and expression, including insect cell and mammalian expression systems.
Proficiency in different protein purification techniques such as affinity, ion exchange, and gel filtration chromatography using FPLC or HPLC systems.
Understanding of protein characterization as well as protein-ligand interactions using biophysical methods (e.g., SPR, DSF, ITC, LC/MS).
Demonstrated critical thinking and troubleshooting ability when handling challenging proteins such as aggregated proteins, multicomponent complexes, or membrane proteins.
Passionate about biomedical research and drug discovery. Motivated to learn new techniques in protein biochemistry, biophysics, and structural biology.
Excellent communication skills, both oral and written, and ability to work effectively in a matrix team environment.

Desirable Requirements:

Experience in protein crystallography, bio-NMR, or cryo-EM, either directly or working closely with others.
Experience in biophysical methods to characterize protein-protein or protein-ligand interactions.

Compensation and Benefits:

The salary for this position is expected to range between $93,800 and $174,200 per year for Senior Scientist I, and $98,700 and $183,300 for Senior Scientist II. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

To learn more about the culture, rewards and benefits we offer our people click here.

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture

Benefits and Rewards: Learn about all the ways we’ll help you thrive personally and professionally.
Read our handbook (PDF 30 MB)

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.

Accessibility & Reasonable Accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Division

Biomedical Research

Business Unit

Research

Location

USA

State

California

Site

San Diego

Company / Legal Entity

U175 (FCRS = US175) Novartis Institutes for BioMedical Research, Inc.

Functional Area

Research & Development

Job Type

Full time

Employment Type

Regular

Shift Work

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Refine Your Search

novartis jobs in california

Senior Scientist, Protein Production

Computational Medicinal Chemist

Director Pathology

Head, Oncology Drug Discovery – San Diego

Data Science, Cheminformatics & AI: Lab-in-the-Loop Hit Finding

Principal Scientist, Structural Biology

Lab Automation & Logistics Delivery Lead

Manager, QA Method Validation

Production Support Supervisor, Nights

Innovation Postdoctoral Fellow, Data Science & AI Vision Foundation Models for Cellular Imaging in AI Drug Discovery

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