Top 56 Senior program director Jobs in Chicago Il

Director/Senior Director, Preclinical Program Leadership
EVOZYNE INC —Chicago, IL
- $175,000 - $250,000 a year
- Remote
- 11+ years
- Master's degree
- Doctor of Philosophy
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Senior Director, Program Operations
Braven —Chicago, IL
- $105,500 - $139,100 a year
- Weekends as needed
- Hybrid work
- Bachelor of Science
- System design
- Office
- Paid parental leave
- Health insurance
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Senior Program Manager, Transformation Office
Northern Trust Corp. —Chicago, IL
- $137,400 - $240,400 a year
- Call employer
- Analysis skills
- Bachelor's degree
- US work authorization
- Health insurance
- Dental insurance
Senior Director of Program Strategy & Impact
Centers For New Horizons Inc —Chicago, IL
- $100,000 - $120,000 a year
- Full-time
- Children
- Senior level
- Leadership
10d
Senior Director of Program Operations
The Salvation Army Central Territory —Chicago, IL
- $116,207 - $145,259 a year
- 7 years
- Office
- Master's degree
- Disability insurance
- Health insurance
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Senior Manager, China-U.S. TNE Program Director
Phoenix Tree Publishing, Inc. —Chicago, IL
- From $150,000 a year
- Full-time
- 5 years
- English
- Bachelor's degree
- Paid time off
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7d
Senior Program Manager - Enterprise PMO
United Airlines —Chicago, IL
- $127,870 - $166,492 a year
- Full-time
- Hybrid work
- 5 years
- Office
- Presentation skills
- Paid holidays
- Disability insurance
5d
Senior Program Manager
Clearwater Analytics, LLC —Chicago, IL
- $120,000 - $168,000 a year
- Full-time
- Continuous improvement
- APIs
- Senior level
- Disability insurance
- Health insurance
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Senior Program Manager, Worldwide Grocery Real Estate, Retail Development PMO
Amazon.com Services LLC —Chicago, IL
- $115,600 - $160,000 a year
- Full-time
- Organizational skills
- Senior level
- Business
- AD&D insurance
- Health insurance
10d
Sr. Non-Retail Program Manager, WWGS - Facility Operations Support
Amazon.com Services LLC —Chicago, IL
- $104,100 - $185,000 a year
- Full-time
- Bachelor's degree
- Senior level
- Business
- AD&D insurance
- Health insurance
Sr Program Mgr DEI
Hospital: Rush University Medical Center —Chicago, IL
- $55.16 - $80.05 an hour
- 8 hour shift
- 3 years
- Master's degree
- Bachelor's degree
13d
Senior Program Manager- Community & Healthcare Integration
Illinois Public Health Institute —Chicago, IL
- Full-time
- Continuous improvement
- Training & development
- Senior level
Quick Apply
Senior Program Manager-Games
Mob Entertainment —Chicago, IL
- $100,000 - $130,000 a year
- Full-time
- Remote
- Google Workspace
- 7 years
- Continuous improvement
- Profit sharing
- Health savings account
Senior Manager, Data Program Management
West Monroe —Chicago, IL
- $203,200 - $239,100 a year
- Email
- Hybrid work
- Azure
- Up to 50% travel
- Office
Quick Apply
Senior Project/Program Manager
MCKISSACK & MCKISSACK —Chicago, IL
- $150,000 - $200,000 a year
- Urgently hiring
- Analysis skills
- Continuous improvement
- Travel
- Commuter assistance
- Health savings account
Quick Apply
7d
Program Manager, Senior
Independence Pet Group —Chicago, IL
- Full-time
- Hybrid work
- 11+ years
- Master's degree
- Bachelor's degree
- Commuter assistance
- Paid parental leave
Senior Government Programs Manager
PsiQuantum —Chicago, IL
- $140,000 - $163,000 a year
- Email
- 7 years
- Bachelor of Science
- Bachelor's degree
Senior Program Manager - Performance Management
Illinois Public Health Institute —Chicago, IL
- Full-time
- Senior level
- Communication skills
- Public Health
Quick Apply
Sr. Program Manager, Health Science
American Heart Association —Chicago, IL
- $90,000 - $110,000 a year
- Full-time
- Remote
- Microsoft Excel
- 5 years
- Research
- Wellness program
- Paid holidays
Senior Enablement Program Manager, PEO Account Management
Rippling —Chicago, IL
- $145,000 - $180,000 a year
- Full-time
- Hybrid work
- 5 years
- Office
- Experience equivalent to degree accepted
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senior program director jobs near chicago il

Director/Senior Director, Preclinical Program Leadership

EVOZYNE INC
Chicago, IL

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Job Details

$175,000 - $250,000 a year

Qualifications

FDA submissions
Project development phase management
GxP
Clinical development
Investigational new drug (IND) applications
ICH guidelines
Vendor relationship management
Leading team collaboration initiatives
Regulatory submissions
Cross-functional team management
Pharmaceutical research experience
Project stakeholder communication
Cross-functional communication

Full Job Description

Evozyne is an AI-native biotech company building a new way to design therapeutic proteins. Our generative AI platform was purpose-built to create entirely novel proteins that expand what’s possible beyond traditional drug discovery. We are applying this platform to develop transformative therapies for serious diseases with significant unmet need, working at the intersection of AI, biology, and protein engineering to solve complex scientific problems that conventional approaches cannot easily address.

As the Director/Senior Director, Preclinical Program Leadership, you will own the operations and execution of advancing therapeutic assets from candidate nomination through IND submission across multiple programs. You will play a central role in efficiently moving programs toward the clinic while helping shape how program leadership operates and scales within the company.

Reporting to the Chief Operating Officer, you will bring deep experience in preclinical program leadership, IND enablement, strong strategic and operational judgment, and clear communication to ensure programs progress effectively across complex, interdependent workstreams.

Location: Remote

What You’ll Do

Own program execution and operations from candidate nomination through IND clearance and Phase 1 enablement across multiple assets in parallel
Drive the critical path, including timelines, budgets, dependencies, and decision points
Build and maintain integrated development plans spanning workstreams across multple functional areas
Translate program progress into clear, actionable updates and recommendations for leadership
Own external partnerships with CROs and CDMOs, including vendor selection, scope definition, and ongoing performance management
Negotiate scope, cost, timelines, and deliverables, and hold partners accountable to outcomes
Coordinate across multiple vendors simultaneously, managing handoffs, data flow, and interdependencies
Partner with internal technical experts to design studies and translate program needs into effective external workstreams
Oversee development of study protocols, incorporating cross-functional input and aligning stakeholders
Build the internal playbooks, processes, and operating structures needed to scale program execution across the pipeline

Who You Are

You are the central operator in all aspects of advancing IND programs, bringing in internal stakeholders, external consultants, and technical partners as needed. You thrive in a dynamic environment where you’re balancing speed, cost, and risk to ensure successful IND submissions. You think big on high-level regulatory and technical strategy while maintaining the attention to detail required to plan multiple steps ahead. You have a strong ownership mentality acting as the operational leader for our preclinical programs.

Required Experience

Direct operational ownership of multiple IND programs in biologics, with at least one specifically in functional protein therapeutics
Advanced degree in biochemical, pharmacology, toxicology or related field such as biology and life sciences
8+ years (Ph.D.) to 12+ years (Master’s) of relevant industry experience
Demonstrated success leading programs through CROs and CDMOs, including global vendors.
Deep understanding of the drug development process from discovery through IND filing
Strong familiarity with GxP, ICH guidelines, and FDA preclinical requirements
Proven ability to align and influence stakeholders across functions and organizations

What We’re Looking For

Strong strategic and operational judgment
Clear, concise communicator who can simplify complex programs
Highly organized and detail-oriented, with the ability to anticipate challenges
Hands-on leader who is comfortable owning outcomes directly
Effective at influencing without formal authority
Comfortable operating in a fast-moving, evolving environment

Why Evozyne

Opportunity to drive multiple programs from candidate nomination through IND and into the clinic in a highly integrated, fast-moving environment
Ability to work at the intersection of AI, biology, and experimental science on problems where the path forward is not always clear
Significant ownership and influence on how preclinical programs are executed, prioritized, and scaled as the pipeline grows
Exposure to both strategic decisions and hands-on execution in a lean team where your work directly impacts program outcomes

Additional Information
Compensation Range: $175,000 - $250,000.

Individual compensation within this range is determined by a combination of factors, including but not limited to level, years of relevant job-related experience, and internal equity. This is what we believe in good faith is the range of possible base salary for this role at the time of this posting. We may ultimately pay more or less than the posted range. This range may be modified in the future.

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Refine Your Search

senior program director jobs in chicago il

Director/Senior Director, Preclinical Program Leadership

Senior Director, Program Operations

Senior Program Manager, Transformation Office

Senior Director of Program Strategy & Impact

Senior Director of Program Operations

Senior Manager, China-U.S. TNE Program Director

Senior Program Manager - Enterprise PMO

Senior Program Manager

Senior Program Manager, Worldwide Grocery Real Estate, Retail Development PMO

Sr. Non-Retail Program Manager, WWGS - Facility Operations Support

Sr Program Mgr DEI

Senior Program Manager- Community & Healthcare Integration

Senior Program Manager-Games

Senior Manager, Data Program Management

Senior Project/Program Manager

Program Manager, Senior

Senior Government Programs Manager

Senior Program Manager - Performance Management

Sr. Program Manager, Health Science

Senior Enablement Program Manager, PEO Account Management

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