Top 5 Principal chemist Jobs in Exton, Pa

Scientist/Sr. Scientist/Principal Scientist
Frontage Laboratories —Exton, PA
- Full-time
- Master's degree
- Bachelor's degree
- Doctor of Philosophy
- Disability insurance
- Health insurance
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Principal Scientist- Sterile and Drug Product Development
GlaxoSmithKline —Upper Providence, PA
- Full-time
- 5 years
- Bachelor of Science
- Analysis skills
2d
Associate Principal Scientist, Mass Spectrometry
Merck —West Point, PA
- $142,400 - $224,100 a year
- Full-time
- 5 years
- Bachelor of Science
- Analysis skills
- Paid holidays
- Health insurance
Principal Scientist, Vaccine Drug Product Development
Merck —West Point, PA
- $173,200 - $272,600 a year
- Full-time
- Bachelor of Science
- 8 years
- Bachelor's degree
- Paid holidays
- Health insurance

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Scientist/Sr. Scientist/Principal Scientist
Frontage Laboratories —Exton, PA
Ph.D. in Analytical Chemistry, Biochemistry, Pharmacology or related scientific discipline with 1-2+ years direct experience, OR Master’s degree in same…
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Scientist/Sr. Scientist/Principal Scientist

Frontage Laboratories -
Exton, PA

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Job Details

Full-time

Benefits

Disability insurance
Health insurance
Dental insurance
401(k)
Life insurance

Qualifications

Research design
Laboratory experiment design
GLP
High-performance liquid chromatographs
Design of experiments
Protein analysis (analytical chemistry specialty)
Research project design
Biochemical laboratory techniques
Pharmaceutical analysis
Materials analysis (analytical chemistry specialty)
Mass spectrometers (MS)
Verification of laboratory test methods
Test validation method
Research findings presentation
Data analysis software

Full Job Description

Scientist/ Senior Scientist/ Principal Scientist, method Developer, Large Molecules Quantitation by LC-MS/MS, Bioanalytical Services

Location: Exton, PA (Corporate)

Full time

Responsibilities:

Mainly responsible for developing bioanalytical quantitation methods for large molecules, such as peptides, protein biomarkers, Oligos, mAbs, ADCs or sugar, lipids, etc in biological matrices using LC-MS/MS platform with triple quadrupole MS and with HRMS.
Directly working with method development team head to design the experimental activities to address the bioanalytical challenges of the method, conduct the experiments, summarize the method development results, discussion with the team head of the experimental results and present the results internally and to sponsors.
Simultaneously handle multiple method development projects or method qualification/method validation as required. Coordinate study activities with supervisor and internal team to ensure efficiency and quality of the projects within the timeline.
Coordinate with internal team, like PI and PMs, to deliver the established methods to internal team for method validation and sample analysis within the expected timeline. Provide technical support and troubleshooting in cases the method performance does not meet the expectation.
Keep track of industry trending on the quantitation of large molecules using LC-MS platform. Assess, evaluate and implement new technologies or instruments in the GLP labs to improve the analysis efficiency or data quality.
Set-up, utilize, and maintain complex instrumentation Follow safety precautions

Education and Requirements:

Prior working experience working large molecules, such as peptides, Oligos, mAbs, ADCs or sugar, lipids, etc in the regulated BioA lab for at least 1 year experience.
Prior working experience in LC-triple quadrupole MS. The experience with HRMS is a plus. Experience with Sciex QTOF instrument and/or Thermo Orbitrap Exploris HRMS is an additional plus. The experience with microflow or nanoflow LC is a plus.
Prior experience developing and validating bio-analytical methods for the quantitation of small molecules and large molecules in biological matrices using LC-MS/MS platform in a GLP lab.
Experience using Sciex Analyst software, OS software, and Thermo Chromeleon and Watson LIMS is a plus
Proven ability to successfully work in a team environment. Excellent oral and written communication skills. Understanding of experimental design and planning, data collection and summarize the experimental results and presentation skills, and familiar with common data analysis software
Ph.D. in Analytical Chemistry, Biochemistry, Pharmacology or related scientific discipline with 1-2+ years direct experience, OR Master’s degree in same disciplines with 2-4+ years direct experience in large molecules quantitation field using LC-MS/MS platform, OR Bachelor’s degree in same discipline with 5+ years direct experience in large molecules quantitation field using LC-MS/MS platform.

Salary and Benefits:

Frontage Laboratories offers a competitive compensation and generous benefits package including health and dental insurance, a 401(k) plan, health insurance, short and long-term disability insurance, life insurance etc.

Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.

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Refine Your Search

principal chemist jobs in exton, pa

Scientist/Sr. Scientist/Principal Scientist

Principal Scientist- Sterile and Drug Product Development

Associate Principal Scientist, Mass Spectrometry

Principal Scientist, Vaccine Drug Product Development

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