Top 21 Principal scientist Jobs in Exton Pa

Scientist/Sr. Scientist/Principal Scientist
Frontage Laboratories —Exton, PA
- Full-time
- Master's degree
- Bachelor's degree
- Doctor of Philosophy
- Disability insurance
- Health insurance
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Senior Scientist/Principal Scientist- Biotransformation/Met ID
Frontage Laboratories —Exton, PA
- Full-time
- Doctor of Philosophy
- Senior level
- Communication skills
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Principal Scientist
Frontage Laboratories —Exton, PA
- Full-time
- 5 years
- Doctor of Philosophy
- Senior level
- Disability insurance
- Health insurance
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Associate Principal Scientist, Toxicology/Study Director
Merck —West Point, PA
- $142,400 - $224,100 a year
- Full-time
- Master's degree
- 8 years
- Fair chance
- Paid holidays
- Health insurance
2d
Principal Biostatistician
Penfield Search Partners —Philadelphia, PA
- 6 years
- Management
- Doctor of Philosophy
Quick Apply
Principal Scientist- Sterile and Drug Product Development
GlaxoSmithKline —Upper Providence, PA
- Full-time
- 5 years
- Bachelor of Science
- Analysis skills
10d
Principal Scientist, Oncology Data Science (Translational Science)
GlaxoSmithKline —Upper Providence, PA
- $121,275 - $202,125 a year
- Full-time
- Computer science
- Computer Science
- Writing skills
- Paid holidays
- Health insurance
Principal Data Analyst
University of Pennsylvania —Philadelphia, PA
- $83,500 - $104,792 a year
- Full-time
- Background check
- University
- Bachelor's degree
- Health insurance
- Dental insurance
Upstream Principal Scientist, Vector Biology
Legend Biotech US —Philadelphia, PA
- $146,410 - $192,164 a year
- Full-time
- 5 years
- Doctor of Philosophy
- US work authorization
Quick Apply
Principal Researcher, Downstream Process Development - Biologics
Eisai —Exton, PA
- $80,200 - $105,200 a year
- Full-time
- 5 years
- Bachelor of Science
- Analysis skills
Principal Investigator, Translational Biomarker Discovery Laboratory
Incyte Corporation —Wilmington, DE
- 3 years
- Doctor of Philosophy
- Mentoring
Principal Scientist (Ph.D.)
Exponent Inc. —Philadelphia, PA
- Email
- Office
- Analysis skills
- Doctor of Philosophy
Principal Regulatory Scientist
Exponent Inc. —Philadelphia, PA
- Email
- Office
- Master's degree
- Doctor of Philosophy
- 401(k)
14d
Senior Principal Scientist, Veterinary Pathology Board Certified
Merck —West Point, PA
- $231,900 - $365,000 a year
- Full-time
- Hybrid work
- Doctor of Philosophy
- Mentoring
- Fair chance
- Paid holidays
- Health insurance
2d
Principal Investigator / Sr. Principal Investigator, Clinical Pharmacology & Pharmacometrics
Incyte Corporation —Wilmington, DE
- Medicine
- 3 years
- Doctor of Philosophy
Sr. Principal Statistician, Biostatistics
Jazz Pharmaceuticals —Philadelphia, PA
- $156,000 - $234,000 a year
- Remote
- Analysis skills
- Doctor of Philosophy
- Senior level
- Health insurance
- Dental insurance
Principal eClinical Data Strategist
Almac Group —Lansdale, PA
- Email
- Hybrid work
- Office
- Master's degree
- SQL
- Disability insurance
- Health insurance
Quick Apply
Principal Scientist - Safety Surveillance and Risk Assessment
Altria —United States
- $132,500 - $202,100 a year
- Full-time
- Presentation skills
- Doctor of Philosophy
- Senior level
- Profit sharing
- Paid parental leave

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principal scientist jobs near exton pa

Scientist/Sr. Scientist/Principal Scientist

Frontage Laboratories -
Exton, PA

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Job Details

Full-time

Benefits

Disability insurance
Health insurance
Dental insurance
401(k)
Life insurance

Qualifications

Research design
Laboratory experiment design
GLP
High-performance liquid chromatographs
Design of experiments
Protein analysis (analytical chemistry specialty)
Research project design
Biochemical laboratory techniques
Pharmaceutical analysis
Materials analysis (analytical chemistry specialty)
Mass spectrometers (MS)
Verification of laboratory test methods
Test validation method
Research findings presentation
Data analysis software

Full Job Description

Scientist/ Senior Scientist/ Principal Scientist, method Developer, Large Molecules Quantitation by LC-MS/MS, Bioanalytical Services

Location: Exton, PA (Corporate)

Full time

Responsibilities:

Mainly responsible for developing bioanalytical quantitation methods for large molecules, such as peptides, protein biomarkers, Oligos, mAbs, ADCs or sugar, lipids, etc in biological matrices using LC-MS/MS platform with triple quadrupole MS and with HRMS.
Directly working with method development team head to design the experimental activities to address the bioanalytical challenges of the method, conduct the experiments, summarize the method development results, discussion with the team head of the experimental results and present the results internally and to sponsors.
Simultaneously handle multiple method development projects or method qualification/method validation as required. Coordinate study activities with supervisor and internal team to ensure efficiency and quality of the projects within the timeline.
Coordinate with internal team, like PI and PMs, to deliver the established methods to internal team for method validation and sample analysis within the expected timeline. Provide technical support and troubleshooting in cases the method performance does not meet the expectation.
Keep track of industry trending on the quantitation of large molecules using LC-MS platform. Assess, evaluate and implement new technologies or instruments in the GLP labs to improve the analysis efficiency or data quality.
Set-up, utilize, and maintain complex instrumentation Follow safety precautions

Education and Requirements:

Prior working experience working large molecules, such as peptides, Oligos, mAbs, ADCs or sugar, lipids, etc in the regulated BioA lab for at least 1 year experience.
Prior working experience in LC-triple quadrupole MS. The experience with HRMS is a plus. Experience with Sciex QTOF instrument and/or Thermo Orbitrap Exploris HRMS is an additional plus. The experience with microflow or nanoflow LC is a plus.
Prior experience developing and validating bio-analytical methods for the quantitation of small molecules and large molecules in biological matrices using LC-MS/MS platform in a GLP lab.
Experience using Sciex Analyst software, OS software, and Thermo Chromeleon and Watson LIMS is a plus
Proven ability to successfully work in a team environment. Excellent oral and written communication skills. Understanding of experimental design and planning, data collection and summarize the experimental results and presentation skills, and familiar with common data analysis software
Ph.D. in Analytical Chemistry, Biochemistry, Pharmacology or related scientific discipline with 1-2+ years direct experience, OR Master’s degree in same disciplines with 2-4+ years direct experience in large molecules quantitation field using LC-MS/MS platform, OR Bachelor’s degree in same discipline with 5+ years direct experience in large molecules quantitation field using LC-MS/MS platform.

Salary and Benefits:

Frontage Laboratories offers a competitive compensation and generous benefits package including health and dental insurance, a 401(k) plan, health insurance, short and long-term disability insurance, life insurance etc.

Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.

Quick Apply

Refine Your Search

principal scientist jobs in exton pa

Scientist/Sr. Scientist/Principal Scientist

Senior Scientist/Principal Scientist- Biotransformation/Met ID

Principal Scientist

Associate Principal Scientist, Toxicology/Study Director

Principal Biostatistician

Principal Scientist- Sterile and Drug Product Development

Principal Scientist, Oncology Data Science (Translational Science)

Principal Data Analyst

Upstream Principal Scientist, Vector Biology

Principal Researcher, Downstream Process Development - Biologics

Principal Investigator, Translational Biomarker Discovery Laboratory

Principal Scientist (Ph.D.)

Principal Regulatory Scientist

Senior Principal Scientist, Veterinary Pathology Board Certified

Principal Investigator / Sr. Principal Investigator, Clinical Pharmacology & Pharmacometrics

Sr. Principal Statistician, Biostatistics

Principal eClinical Data Strategist

Principal Scientist - Safety Surveillance and Risk Assessment

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