Top 100 Laboratory director Jobs in Framingham Ma

Director, AIRx Medicinal Chemistry
Takeda Pharmaceutical —Boston, MA
- $177,000 - $278,080 a year
- Hybrid work
- Management
- Bachelor of Science
- 11+ years
- Paid holidays
- Disability insurance
Program Director - Life Sciences
UG2 LLC —Cambridge, MA
- $175,000 a year
- Engineering
- Ability to lift 50 pounds
- Mentoring
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Senior Director, AIRx Medicinal Chemistry
Takeda Pharmaceutical —Boston, MA
- $212,000 - $333,190 a year
- Full-time
- Hybrid work
- Management
- 11+ years
- Doctor of Philosophy
- Paid holidays
- Disability insurance
Senior Director, Quality Control
EPM Scientific —Boston, MA
- Contract
- Bachelor's degree
- Mentoring
- US work authorization
Quick Apply
6d
Director, Change Management - Labs of Tomorrow
Takeda Pharmaceutical —Boston, MA
- $177,000 - $278,080 a year
- Full-time
- 18 years or older
- 5 years
- Analysis skills
- Paid holidays
- Disability insurance
High Complex CLIA LAB: Lab Director
Nanobiosym —Cambridge, MA
- From $150,000 a year
- Part-time
- Medicine
- 8 years
- Doctor of Philosophy
Quick Apply
Senior Director, QC Laboratory
Candel Therapeutics —Needham, MA
- $258,000 - $285,000 a year
- Full-time
- Hybrid work
- Microsoft Excel
- Bachelor's degree
- Mentoring
Assistant Director of Dental Laboratory Operations
Tufts University —Boston, MA
- $108,200 - $162,400 a year
- 5 years
- Bachelor's degree
- In-person
Director, Microbiology
Rapid Micro Biosystems —Lexington, MA
- $173,000 - $230,000 a year
- Full-time
- Hybrid work
- Master's degree
- Analysis skills
- Bachelor's degree
Quick Apply
Sr Principal Scientist / Associate Director, Biomarker Assay Development Laboratory
Novartis —Cambridge, MA
- $152,600 - $283,400 a year
- Full-time
- Medicine
- Continuous improvement
- Doctor of Philosophy
- Paid parental leave
- Parental leave
6d
CLIA Lab Director
Valius Sciences —Boston, MA
- $200,000 - $300,000 a year
- Full-time
- 8 years
- Doctor of Philosophy
- Recruiting
- Health insurance
- Dental insurance
Quick Apply
Director, Analytical Development
Keros Therapeutics —Lexington, MA
- $200,000 - $226,000 a year
- Analysis skills
- Doctor of Philosophy
- Mentoring
11d
Director, Analytical Development and Validation, Tech Ops (Biologics)
Oruka Therapeutics —Waltham, MA
- $213,000 - $240,000 a year
- Hybrid work
- 7 years
- Office
- Master's degree
Associate Director, Laboratory Informatics and Platform Automation
Valo Health —Lexington, MA
- $195,500 - $230,000 a year
- Bachelor of Science
- Laboratory experience
- Bachelor's degree
- Retirement plan
Sr. Director, Quality Assurance for Quality Control
Vaxcyte —Boston, MA
- $229,000 - $268,000 a year
- Remote
- 11+ years
- Bachelor's degree
- Senior level
6d
Director, Clinical Quality Assurance
Oruka Therapeutics —Waltham, MA
- $213,000 - $240,000 a year
- Remote
- Nursing
- Bachelor's degree
- Travel
Associate Director, Project Representative/Lab Manager
Merck KGaA —Billerica, MA
- $164,600 - $246,800 a year
- English
- Doctor of Philosophy
- Neurology
- Health insurance
- Paid time off
12d
Associate Director, Program Portfolio - Research
Bose —Framingham, MA
- $228,600 - $314,400 a year
- Full-time
- Computer Science
- Research
- Office
- Health insurance
- 401(k)
Sr. Principal Scientist / Director, DMPK & Bioanalytical Sciences
Flagship Pioneering, Inc. —Cambridge, MA
- $179,000 - $236,000 a year
- Management
- 8 years
- Supervising experience
- Retirement plan
Raven StealthCo- Director, Oligonucleotide and Conjugation Chemistry
Raven —Cambridge, MA
- $210,000 - $235,000 a year
- Bachelor of Science
- 8 years
- Bachelor's degree
Quick Apply

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laboratory director jobs near framingham ma

Director, AIRx Medicinal Chemistry

Takeda Pharmaceutical -
Boston, MA

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Job Details

$177,000 - $278,080 a year

Benefits

Paid holidays
Disability insurance
Health insurance
Dental insurance
Tuition reimbursement
Paid time off
Vision insurance
401(k) matching
Volunteer time off
Life insurance

Qualifications

AI models
Program management
Management
In silico prediction
AI tools proficiency
Pharmaceutical company experience
Pharmaceutical research experience

Full Job Description

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

Director, AIRx Medicinal Chemistry

Takeda Research is constructing the Discovery Automation & Robotics (DAR) group built on AI, automation, new ways of working, and talent with the singular vision of delivering differentiated medicines to the clinic at speed and cost. To catalyze these efforts, Takeda is creating two complementary units: AI Research Accelerator (AIRx) and The Discovery Automation & Robotics (DAR) group.

AIRx will consist of a dedicated group of experienced drug hunters with the autonomy of a biotech and the resources of a leading pharmaceutical company. It is designed to incubate the future AI-powered operating models and deliver candidates to the clinic at industry leading speed and success rates.

Purpose

This is medicinal chemistry as it should be — pure design, at speed, with the best tools available. You will work at the frontier of AI-enabled molecular design: evaluating generative proposals, applying deep SAR judgment, and directing CRO synthesis to close DMTA cycles faster than any traditional discovery team. No synthetic bench. No compound store. Just expert chemistry thinking applied at maximum velocity.

The AIRx Medicinal Chemist is a seasoned drug hunter who thrives in lean, autonomous environments and is excited to work at the frontier of AI-driven drug design. Strong SAR intuition, decisiveness, and the confidence to challenge computational outputs are as important as deep chemistry expertise. We are not looking for someone who will defer to the AI. We are looking for someone who will argue with it, stress-test its proposals against hard-won SAR experience, and make better molecules because of that tension. If you have deep chemistry instinct and genuine curiosity about what generative AI can and cannot do — this is where that combination produces real impact.

Accountabilities

Design and optimize drug candidates using deep SAR intuition, multi-parameter optimization, and ADME-embedded design principles
Integrate AI/ML-generated design proposals with medicinal chemistry judgment — critically evaluating computational outputs, not simply accepting them
Partner closely with Computational Chemistry colleagues to close DMTA cycles rapidly; contribute to defining next design iterations
Provide strategic oversight of CRO synthesis programs: define compound lists, review synthetic routes, and ensure quality and delivery timelines
Embed selectivity, developability, and IP considerations into design decisions from the outset
Interpret structural biology data (X-ray, cryo-EM) in partnership with Structural Biology contacts to guide optimization
Stay current with competitive chemical matter and emerging chemistry approaches; proactively apply new methods
Contribute to AI/ML training datasets by ensuring experimental data is captured in standardized, decision-ready format

Qualifications & Competencies

PhD in medicinal chemistry or organic chemistry
10+ years of drug discovery experience with a strong track record in lead optimization and candidate nomination OR
MS with 16+ years experience, OR BS with 18+ years experience
Demonstrated expertise in SAR-driven design, ADME optimization, and multi-parameter optimization across multiple programs
Experience directing CRO-based chemistry programs including synthetic route planning; proven vendor oversight and delivery management
Working knowledge of AI/ML design tools; ability to critically interpret and challenge computational outputs
Familiarity with structure-based drug design; ability to read and apply protein-ligand structural data
Experience in one or more therapeutic areas across the Takeda Research portfolio preferred
Has operated in SWAT team, rapid-response, or focused asset team environments and knows the difference between productive urgency and firefighting — and thrives in the former

ADDITIONAL INFORMATION

The position will be based in Cambridge, MA. This position is currently classified as “hybrid” by Takeda’s Hybrid and Remote Work policy

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$177,000.00 - $278,080.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

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Refine Your Search

laboratory director jobs in framingham ma

Director, AIRx Medicinal Chemistry

Program Director - Life Sciences

Senior Director, AIRx Medicinal Chemistry

Senior Director, Quality Control

Director, Change Management - Labs of Tomorrow

High Complex CLIA LAB: Lab Director

Senior Director, QC Laboratory

Assistant Director of Dental Laboratory Operations

Director, Microbiology

Sr Principal Scientist / Associate Director, Biomarker Assay Development Laboratory

CLIA Lab Director

Director, Analytical Development

Director, Analytical Development and Validation, Tech Ops (Biologics)

Associate Director, Laboratory Informatics and Platform Automation

Sr. Director, Quality Assurance for Quality Control

Director, Clinical Quality Assurance

Associate Director, Project Representative/Lab Manager

Associate Director, Program Portfolio - Research

Sr. Principal Scientist / Director, DMPK & Bioanalytical Sciences

Raven StealthCo- Director, Oligonucleotide and Conjugation Chemistry

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