We are seeking a Medical Lead, Prostate Cancer to join US Medical Affairs in Gaithersburg, Maryland. This is a high-impact leadership role for a medical affairs professional with deep oncology expertise, strong headquarters experience, and a proven ability to shape and execute strategy in a fast-paced environment.
The Medical Lead will serve as the medical leader for a prostate cancer brand and/or indication, with accountability for medical strategy, integrated planning, execution, cross-functional leadership, and budget oversight. This individual will lead the Core Medical Team (CMT), partner closely with Global Medical Affairs, and help ensure that US medical activities are aligned to scientific priorities, evidence needs, and business objectives.
This role is ideal for someone who combines strategic thinking with execution excellence, and who can influence across a complex matrix while maintaining a strong focus on patients, science, and compliant collaboration.
Key Responsibilities
- Lead US Medical Affairs activities for a prostate cancer product or indication, providing medical leadership across strategy and execution.
- Develop and lead integrated medical plans that support key strategic priorities, launch readiness, evidence generation, and scientific engagement.
- Chair and lead the Core Medical Team (CMT), aligning cross-functional stakeholders on strategy, tactics, milestones, and resource needs.
- Drive execution of the medical plan, ensuring activities are timely, compliant, and aligned with medical and business objectives.
- Manage and oversee the medical budget associated with the brand or indication.
- Partner with Global Medical Affairs to align US execution with global strategy, data generation plans, and scientific priorities.
- Collaborate with commercial and cross-functional teams to ensure medically appropriate brand planning and execution.
- Provide medical review and input to ensure scientific accuracy, balance, and integrity of medical and promotional materials, consistent with applicable standards.
- Build and maintain relationships with external experts, academic institutions, professional societies, advocacy organizations, payer and provider stakeholders, and other strategic partners.
- Support medical education and scientific exchange, including advisory boards, speaker training, and other external engagement activities.
- Collaborate on evidence generation plans, including investigator-sponsored research, HEOR initiatives, outcomes studies, and other medical affairs research activities.
- Work closely with field medical teams and key account stakeholders to support a coordinated medical strategy for key external accounts.
- Contribute medical insight into product safety discussions in partnership with Patient Safety colleagues.
Essential Qualifications
- MD, DO, PhD, or PharmD with relevant medical, scientific, or pharmaceutical industry experience.
- 5+ years of relevant experience in the pharmaceutical industry, clinical practice, and/or research, preferably in oncology or another closely related therapeutic area.
- Significant oncology experience, including a strong understanding of disease area strategy and scientific engagement.
- Headquarters-based medical affairs experience, with demonstrated involvement in strategic planning and cross-functional execution.
- Experience supporting a brand, disease area, or indication strategy in a US, regional, or global organization.
- Strong ability to work effectively across cross-functional teams and influence stakeholders without direct authority.
- Excellent written, verbal, interpersonal, and organizational skills.
- Strong business acumen, including awareness of the evolving US payer and provider landscape.
- Ability to travel domestically and internationally, up to approximately 30%.
Preferred Qualifications
- Experience in oncology product launches or pre-launch planning.
- Experience leading integrated medical planning and coordinating execution across multiple stakeholder groups.
- Familiarity with prostate cancer and/or other complex oncology disease areas.
- Experience working with medical evidence generation, HEOR, external sponsored research, or scientific publication planning.
- Knowledge of relevant professional societies, scientific experts, and the broader oncology external landscape.
What You Bring
- A strong commitment to patient outcomes and scientific excellence.
- Strategic agility, including the ability to anticipate, shape, and respond to market and scientific trends.
- Strong leadership presence and the ability to guide teams through complexity.
- Proven ability to engage and influence senior stakeholders across medical, commercial, and global teams.
- Strong collaboration, communication, presentation, and negotiation skills.
- Sound judgment, analytical capability, and a track record of delivering impact.
- The ability to coach, mentor, and elevate those around you.
This is an opportunity to play a central leadership role in a priority area within US Oncology Medical Affairs. You will help shape medical strategy for an evolving prostate cancer portfolio, work at the intersection of science, evidence, launch planning, and cross-functional leadership, and contribute to meaningful outcomes for patients.
The annual base pay for this position ranges from $193,821 - $289,922. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
At AstraZeneca, we change the practice of medicine and improve patient experiences by generating and communicating compelling medical evidence. We translate our wealth of medical and scientific expertise to ensure that the data we produce helps physicians better treat patients at every point in their journey. Our culture is one of openness and transparency, fused with ambition and drive. We are a supportive and trusting place to grow your career, empowering each of us to take a tailored approach to our development.
Date Posted
06-Aug-2026
Closing Date
26-Aug-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
