Top 465 Senior system engineer Jobs in Greenfield, In

Senior Mechanical Engineer
Roche —Indianapolis, IN
- $96,000 - $179,000 a year
- Online Application
- 3 years
- Master's degree
- Doctor of Philosophy
Engineer-Information Services Senior
Indiana University Health —Indianapolis, IN
- Full-time
- 5 years
- System design
- Bachelor's degree
Transportation Senior Continuous Improvement Engineer (remote)
Ryder System —Indianapolis, IN
- $90,000 - $100,500 a year
- Remote
- 5 years
- Engineering
- Dry van
- Disability insurance
- Health insurance
Senior Validation Engineer
INCOG BioPharma Services —Fishers, IN
- Full-time
- Customer service
- Office
- Master's degree
Senior System Engineer
Allison Transmission, Inc. —Indianapolis, IN
- Full-time
- Computer science
- Computer Science
- 5 years
- Wellness program
- Paid parental leave
Senior Product Development and Process Engineer
Amrize —Fishers, IN
- Full-time
- System design
- Residential
- Master's degree
- Paid parental leave
- Health savings account
13d
Senior System Engineer Carmel, United States Jul. 31, 2026
Alter Domus —Carmel, IN
- Hybrid work
- Computer science
- 7 years
- Azure
- Employee assistance program
Senior System Administrator
Rolls-Royce —Indianapolis, IN
- $98,566 - $160,169 a year
- Full-time
- Computer science
- Computer Science
- Master's degree
- Paid parental leave
- Health savings account
3d
Senior Manager Environmental Engineer
Ryder System —Indianapolis, IN
- $140,000 - $160,000 a year
- Microsoft Word
- Engineering
- Travel
- Disability insurance
- Health insurance
Senior Mechanical Engineer
Allegion —Indianapolis, IN
- Online Application
- Hybrid work
- 7 years
- Bachelor of Science
- Analysis skills
- Wellness program
- Health savings account
13d
Senior Controls System Delivery Engineer
Allison Transmission, Inc. —Indianapolis, IN
- Full-time
- Computer science
- Computer Science
- Customer service
- Wellness program
- Paid parental leave
Senior Manufacturing Engineer
Trane Technologies —Noblesville, IN
- $97,406.66 - $156,200.00 a year
- Full-time
- 7 years
- Pass drug screening
- Analysis skills
- Paid holidays
- Health insurance
6d
Senior Process Engineer, Lilly Medicine Foundry
Eli Lilly —Indianapolis, IN
- $66,000 - $171,600 a year
- Full-time
- Bachelor of Science
- Engineering
- Analysis skills
- Health insurance
- Dental insurance
Senior Geotechnical Engineer
SME —Fishers, IN
- Microsoft Outlook
- Management
- Customer service
- Profit sharing
- Health insurance
Quick Apply
Senior Software Engineer
V2X —Indianapolis, IN
- Full-time
- Computer Science
- Mid-level
- Java
11d
Sr. Systems Engineer I
V2X —Indianapolis, IN
- Full-time
- Management
- 5 years
- Engineering
11d
Sr. Principal Systems Engineer
V2X —Indianapolis, IN
- Full-time
- Engineering
- Data analysis skills
- 11+ years
11d
Mechanical Engineer
V2X —Indianapolis, IN
- Full-time
- Engineering
- Research
- 8 years
- Opportunities for advancement
11d
Sr. Systems Engineer II
V2X —Indianapolis, IN
- Full-time
- Engineering
- Data analysis skills
- 8 years
11d
Senior Embedded Firmware Engineer
V2X —Indianapolis, IN
- Full-time
- Computer Science
- 5 years
- Continuous improvement
11d

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Senior Mechanical Engineer

Roche -
Indianapolis, IN

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Job Details

$96,000 - $179,000 a year

Qualifications

Design engineering
Design of individual components
Mechanical knowledge

Full Job Description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

Within the Mechanical Engineering department at Roche R Near Patient Care, you will help develop blood glucose meters, continuous glucose monitoring systems, and related application systems (e.g., test stands) for series production—all in accordance with relevant standards and regulatory guidelines.

As a Senior Mechanical Engineer, you will be an integral member of an agile development team, directly contributing to the creation of high-quality, robust medical devices.

The Opportunity:

You will actively contribute to taking innovative products from the initial idea to series production readiness and successfully launching them on the market. In the agile project team, you will work closely with the other colleagues and will commit to successfully complete the project together as a team.
You are responsible for the development of the mechanical components. You enjoy getting involved in complex mechanical systems and understanding the interactions with other components. To this end, you will perform analyses on complex mechanical components and assemblies, create test plans with DoE, perform the tests, analyze and interpret the test results, and summarize all of this in technical documentation in accordance with regulatory requirements.
You can provide demonstrated knowledge of parametric mechanical CAD design and FEM simulation independently across several projects; through this work, you can incorporate changes resulting from your investigations directly into the product design.
You will work closely with other departments and project teams, including operations and manufacturing. You will build the interface between the development and production teams, which is responsible for the development, construction and implementation of the production line.
You will collaborate with external partners such as injection molding suppliers is an additional aspect of your daily tasks.

Who you are:
(Required)

You have a Bachelor's in mechanical engineering, mechatronics or medical technology (or relevant field of study) with 7+ years of experience; or a Master’s in mechanical engineering, mechatronics or medical technology (or relevant field of study) with 5+ years of experience.
You have 5+ years of professional experience in the development of mechanical components and assemblies. In doing so, you have an affinity for practical activities and like to understand technical matters in detail by practically investigating and testing them.
Ideally, you have a basic level of knowledge of parametric design (Creo Parametrics, Solid Works) and plastics engineering, and have acquired and applied both preferably in a regulated medical device environment.
You are knowledgeable in at least two of the following topics: plastic technology, sterile component design, manufacturing and automated assembly of plastic parts
You are characterized by the ability to work in a team, drive topics independently and self-motivated, have strong communication skills and search for solutions and not for problems. You want to make a difference, are flexible and always keep an open mind even in stressful situations.

Preferred:

You have an advanced degree (e.g. PhD) in mechanical engineering, mechatronics or medical technology or a related field of study with 3+ years of experience.
You have demonstrated experience in the area of agile methods and agile project management.
You have strong interpersonal skills: Outstanding interpersonal, verbal, and written communication and influencing skills: has built and cultivated important relationships both inside an organization and externally. Has proven abilities to influence internal partners and stakeholders; seamlessly collaborates with colleagues/other parts of the organization.

This position is based on-site in Indianapolis, Indiana. It is not a hybrid position.
Relocation benefits are not being offered for this position.

To support initial training and onboarding, a willingness to undertake short-term assignments (3–6 months) at Roche locations in Germany and Switzerland is preferred.

The expected salary range for this position of $96,000 - $179,000 is based on the primary location of Indianapolis, IN. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.

This position also qualifies for the benefits detailed at the link provided below.
Benefits

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this formAccommodations for Applicants.

Apply Now

Refine Your Search

senior system engineer jobs in greenfield, in

Senior Mechanical Engineer

Engineer-Information Services Senior

Transportation Senior Continuous Improvement Engineer (remote)

Senior Validation Engineer

Senior System Engineer

Senior Product Development and Process Engineer

Senior System Engineer Carmel, United States Jul. 31, 2026

Senior System Administrator

Senior Manager Environmental Engineer

Senior Mechanical Engineer

Senior Controls System Delivery Engineer

Senior Manufacturing Engineer

Senior Process Engineer, Lilly Medicine Foundry

Senior Geotechnical Engineer

Senior Software Engineer

Sr. Systems Engineer I

Sr. Principal Systems Engineer

Mechanical Engineer

Sr. Systems Engineer II

Senior Embedded Firmware Engineer

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