Sr. Scientist – Mass Spectrometry
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As a Scientist in a cutting-edge mass spectrometry laboratory, you will develop advanced mass spectrometry-based methods for biotherapeutic product characterization and molecule analysis across all stages of development. You will drive innovation and create technologies that support a diverse research and development pipeline, focusing on complex modalities such as monoclonal antibodies, bispecifics, siRNAs, and AAVs.
Responsibilities
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Design and execute targeted and untargeted small-molecule and elemental analyses on cell culture media and drug molecules using LC-MS, GC-MS, and ICP-MS to support biotherapeutic product development.
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Develop, optimize, and validate advanced mass spectrometry methods to enable robust characterization of biotherapeutic candidates and related materials.
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Provide analytical support to cross-functional teams, including discovery, process development, formulation development, and manufacturing, to address drug development challenges and inform decision-making.
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Independently perform sample preparation and mass spectrometry analyses, ensuring high-quality, reproducible data generation.
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Document experimental procedures, methods, and results in electronic laboratory notebooks (ELN) with clarity and completeness.
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Represent the analytical mass spectrometry function on project teams and serve as a subject matter expert for mass spectrometry-based characterization.
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Prepare and deliver clear, data-driven presentations of experimental results and technical insights at internal and external meetings.
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Contribute to extended characterization of monoclonal antibodies and other biologics by mass spectrometry to support product and process development.
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Collaborate with colleagues to implement and utilize liquid handlers and other laboratory automation tools to increase throughput and efficiency.
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Stay current with advances in mass spectrometry technologies and analytical methodologies and apply relevant innovations to ongoing projects.
Essential Skills
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MS degree in Analytical Chemistry, Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field with at least 5 years of relevant experience, or a PhD in one of these disciplines with 0–2+ years of relevant experience.
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Extensive hands-on experience with advanced mass spectrometry techniques, including method development and analysis using LC-MS, ICP-MS, and/or GC-MS.
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Demonstrated expertise in small molecule characterization, including accurate mass measurement, isotope pattern analysis, and MS/MS fragmentation.
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Proven ability to independently design, conduct, and troubleshoot complex mass spectrometry experiments in a laboratory setting.
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Strong skills in documenting experimental work and results in electronic laboratory notebooks (ELN).
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Experience supporting cross-functional scientific teams with analytical data and interpretation.
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Effective written and verbal communication skills, with the ability to clearly present complex analytical data to diverse audiences.
Additional Skills & Qualifications
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Experience with extended characterization of monoclonal antibodies by mass spectrometry to support product and process development.
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Familiarity with biotherapeutic modalities such as monoclonal antibodies, bispecifics, siRNAs, and AAVs.
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Experience working with liquid handlers and laboratory automation to support high-throughput analytical workflows.
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Understanding in analytical development within a drug development environment, particularly using protein mass spectrometry (LC-MS).
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Ability to collaborate effectively in a multidisciplinary team and contribute to a culture of scientific excellence and innovation.
Job Type & Location
This is a Contract position based out of Tarrytown, NY.
Pay and Benefits
The pay range for this position is $50.00 - $60.00/hr.
Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: • Medical, dental & vision • Critical Illness, Accident, and Hospital • 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available • Life Insurance (Voluntary Life & AD&D for the employee and dependents) • Short and long-term disability • Health Spending Account (HSA) • Transportation benefits • Employee Assistance Program • Time Off/Leave (PTO, Vacation or Sick Leave)
Workplace Type
This is a fully onsite position in Tarrytown,NY.
Application Deadline
This position is anticipated to close on Aug 26, 2026.
About Actalent
Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 20,000 consultants and 5,000 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. We are proud to be an Engineering News-Record (ENR) Top 500 Design Firm for our engineering design services and a ClearlyRated Best of Staffing® winner for both client and talent service.
The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.
If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email [email protected] for other accommodation options.
San Francisco Fair Chance Ordinance: Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the city and county of San Francisco, we will consider for employment qualified applicants with arrest and conviction records.
Massachusetts Lie Detector: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Use of Artificial Intelligence (AI): We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing, screening, and evaluating candidates. AI helps assess applications and qualifications, but final decisions are made by our hiring team. By applying, you acknowledge and agree that your application may be reviewed using AI tools.
