Top 93 Application security engineer Jobs in Lexington, Ky

Principal Application Security Engineer – AI & Agentic Systems
CVS Health —Frankfort, KY
- $144,200 - $288,400 a year
- Full-time
- Azure
- System design
- HIPAA
- Health insurance
- Dental insurance
Help Desk Engineer - 46Solutions
Davis H Elliot Company, Inc. —Lexington, KY
- Weekends as needed
- Computer Science
- Pass drug screening
- Research
- Paid training
- Disability insurance
Principal Application Security Engineer - Threat Research
CVS Health —Frankfort, KY
- $144,200 - $288,400 a year
- Full-time
- Azure
- System design
- HIPAA
- Health insurance
- Dental insurance
Senior Adversary Operations Engineer
CVS Health —Frankfort, KY
- $83,430 - $222,480 a year
- Full-time
- Azure
- HIPAA
- 3 years
- Health insurance
- Dental insurance
Systems Engineer
NV5 —Lexington, KY
- Full-time
- Background check
- Computer science
- Computer Science
- Health insurance
- Dental insurance
Lead Data Privacy Engineer
CVS Health —Frankfort, KY
- $106,605 - $284,280 a year
- Full-time
- Azure
- HIPAA
- 3 years
- Health insurance
- Dental insurance
Hybrid IT Support Technician II - Richmond, KY
Dedicated IT —Richmond, KY
- $60,000 - $70,000 a year
- Full-time
- Hybrid work
- HIPAA
- Mid-level
- Office
- Paid holidays
- Health insurance
Quick Apply
Transportation Engineer Supervisor (Permits)
Commonwealth of Kentucky —Lexington, KY
- $6,880.26 a month
- Full-time
- Construction site
- Engineering
- Mid-level
- Dental insurance
- Vision insurance
1d
Mechanical Engineer Associate / Lexington, KY
Lockheed Martin Corporation —Lexington, KY
- Part-time
- Microsoft Excel
- Mid-level
- Communication skills
- Paid jury duty
- Paid holidays
Staff Cyber Resilience Engineer
Xometry —Lexington, KY
- $205,000 - $233,000 a year
- Hybrid work
- Azure
- 8 years
- Continuous improvement
- Disability insurance
- Health insurance
Quick Apply
Sr. Network Engineer
R.J. Corman Railroad Group LLC- RR Group —Nicholasville, KY
- Full-time
- Pass drug screening
- Office
- Criminal background check
- Paid parental leave
- Health savings account
Quick Apply
Principal Network Engineer - AI Infrastructure
CVS Health —Frankfort, KY
- $144,200 - $288,400 a year
- Full-time
- System design
- HIPAA
- Research
- Health insurance
- Dental insurance
Senior Machine Learning Engineer - Generative AI & Full-Stack Applications
CVS Health —Frankfort, KY
- $83,430 - $222,480 a year
- Full-time
- 3 years
- High school diploma or GED
- Bachelor's degree
- Health insurance
- Dental insurance
Data Analyst Senior
Lockheed Martin Corporation —Lexington, KY
- Part-time
- Azure
- Computer Science
- Research
- Paid jury duty
- Paid holidays
11d
Lead Director - Network and Data Center Engineering
CVS Health —Frankfort, KY
- $144,200 - $288,400 a year
- Full-time
- HIPAA
- High school diploma or GED
- Bachelor's degree
- Health insurance
- Dental insurance
Sr. Mine Engineer
The Shelly Company —Lexington, KY
- Weekends as needed
- Microsoft Excel
- Basic math
- Windows
- Health insurance
- Dental insurance
Quick Apply
Senior Systems Engineer - Special Operations Forces
Lockheed Martin Corporation —Lexington, KY
- Part-time
- Machine learning
- Senior level
- AI
- Paid jury duty
- Paid holidays
Logistics Engineer 2
Ryder System —Georgetown, KY
- $65,000 - $69,000 a year
- Word processing
- Mid-level
- Master's degree
- Disability insurance
- Health insurance
4d
Senior Network Engineer
Toyota Tsusho America, Inc —Georgetown, KY
- Full-time
- Background check
- 7 years
- Computer Science
- Health savings account
- Paid holidays
Quick Apply
3d
Data Engineer Staff
Lockheed Martin Corporation —Lexington, KY
- Part-time
- Azure
- Computer Science
- Office
- Paid jury duty
- Paid holidays
11d

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application security engineer jobs near lexington, ky

Principal Application Security Engineer – AI & Agentic Systems

CVS Health -
Frankfort, KY

Apply Now

Job Details

Full-time
$144,200 - $288,400 a year

Benefits

Health insurance
Dental insurance
Paid time off
Vision insurance

Qualifications

AI models
Cloud security design
Threat Modeling (Architecture security)
AI tools proficiency
Generative models
System design
Microservices
System design for system development
Containerization
Application design
Vulnerability management
Serverless cloud services
Generative AI

Full Job Description

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time.

Position Summary

Development, Standards & Secure Design

Lead development and enforcement of application and AI security policies, standards, and guardrails, embedding security-by-design across both traditional and AI-driven systems.
Establish secure design patterns for AI agent frameworks, covering prompt management, tool invocation, memory handling, autonomy boundaries, and escalation controls.
Promote organization-wide awareness of AI-specific risks such as model misuse, prompt injection, data leakage, and unsafe agent behavior.

AI & Agentic Security Architecture

Serve as the principal SME for securing AI-enabled applications and agentic system architectures.
Architect and review secure designs for systems leveraging LLMs/foundation models, autonomous and semi-autonomous agents, RAG pipelines, and tool‑using or decision‑making workflows.
Define identity, authorization, data access, and observability controls specific to agentic environments while partnering closely with AI platform, product, and data teams to ensure responsible AI delivery.

Collaboration, Leadership & Influence

Influence engineering and product teams to integrate secure engineering practices and align security with compliance, privacy, and responsible AI initiatives.
Advise senior leadership on AI security implications, architectural decisions, and long-term strategy while shaping roadmaps that anticipate emerging AI threats and regulatory requirements.

Testing, Analysis & Risk Management

Lead advanced security testing and risk assessments for AI-enabled systems, including threat modeling of agent workflows, abuse/misuse analysis, and secure design reviews of AI pipelines.
Evaluate and guide adoption of new AI security tools, ensuring protections maintain confidentiality, integrity, availability, and responsible data use.

Operational Response & Continuous Improvement

Provide senior technical leadership during incidents involving application or AI systems, guiding response strategies for misuse, data exposure, and autonomous failures.
Translate operational learnings into improved security architecture, controls, and system resilience.

Mentorship, Innovation & Strategy

Mentor senior and principal engineers to elevate security maturity across the organization.
Contribute to research and evaluation of emerging AI security practices and play a key role in shaping the long-term application and AI security roadmap, advocating for security as a strategic accelerator for AI adoption.

Required Qualifications

10+ years of experience designing, building, and securing large-scale applications and platforms.
7+ years of expertise in application security, including threat modeling, secure design, and vulnerability management.
7+ years of programming experience in one or more languages such as Python, Java, JavaScript, C#, or Go.
5+ years of experience of developing and securing AI and ML workloads, with recent experience in generative AI and agentic workloads.
5+ years of experience public cloud platforms (AWS, Azure, and/or GCP) and modern application architectures.
3+ years of experience with containerized, serverless, and microservice-based architectures.

Preferred Qualifications

Hands-on experience securing AI agents, RAG pipelines, and tool-using LLM systems.
Proven ability to lead complex security initiatives from concept through enterprise-scale adoption.
Familiarity with AI governance, responsible AI principles, and emerging AI security standards.
Experience integrating security controls into CI/CD pipelines for AI and application workloads.
Strong understanding of compliance frameworks (PCI, HIPAA, NIST, HITRUST, CSA).
Experience influencing security strategy beyond a single team, including enterprise or platform-level impact.
Contributions to security research, open-source projects, or industry communities.

Education

Bachelor’s degree or equivalent experience (High School Diploma and 4 years relevant experience)

Pay Range

The typical pay range for this role is:

$144,200.00 - $288,400.00

This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, geography and other relevant factors. This position is eligible for a CVS Health bonus, commission or short-term incentive program in addition to the base pay range listed above. This position also includes an award target in the company’s equity award program.

Our people fuel our future. Our teams reflect the customers, patients, members and communities we serve and we are committed to fostering a workplace where every colleague feels valued and that they belong.

Great benefits for great people

We take pride in offering a comprehensive and competitive mix of pay and benefits that reflects our commitment to our colleagues and their families.

This full‑time position is eligible for a comprehensive benefits package designed to support the physical, emotional, and financial well‑being of colleagues and their families. The benefits for this position include medical, dental, and vision coverage, paid time off, retirement savings options, wellness programs, and other resources, based on eligibility.

Additional details about available benefits are provided during the application process and on Benefits Moments.

We anticipate the application window for this opening will close on: 08/10/2026

Qualified applicants with arrest or conviction records will be considered for employment in accordance with all federal, state and local laws.

Apply Now

Refine Your Search

application security engineer jobs in lexington, ky

Principal Application Security Engineer – AI & Agentic Systems

Help Desk Engineer - 46Solutions

Principal Application Security Engineer - Threat Research

Senior Adversary Operations Engineer

Systems Engineer

Lead Data Privacy Engineer

Hybrid IT Support Technician II - Richmond, KY

Transportation Engineer Supervisor (Permits)

Mechanical Engineer Associate / Lexington, KY

Staff Cyber Resilience Engineer

Sr. Network Engineer

Principal Network Engineer - AI Infrastructure

Senior Machine Learning Engineer - Generative AI & Full-Stack Applications

Data Analyst Senior

Lead Director - Network and Data Center Engineering

Sr. Mine Engineer

Senior Systems Engineer - Special Operations Forces

Logistics Engineer 2

Senior Network Engineer

Data Engineer Staff

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