Top 339 Applied scientist Jobs in Manchester, Wa

Immunology Senior Research Scientist - Flow Cytometry
Vertex Pharmaceuticals —Seattle, WA
- $124,200 - $186,400 a year
- Full-time
- Master's degree
- Analysis skills
- Bachelor's degree
- Loan repayment program
- Dental insurance
Immunology Senior Research Scientist - Single-Cell Genomics
Vertex Pharmaceuticals —Seattle, WA
- $124,200 - $186,400 a year
- Full-time
- Master's degree
- Analysis skills
- Bachelor's degree
- Loan repayment program
- Dental insurance
Research Scientist
Committee for Children —Seattle, WA
- $84,000 - $100,000 a year
- Full-time
- Remote
- Mid-level
- Microsoft Office
- 3 years
- Paid holidays
- Disability insurance
6d
Applied Scientist
Microsoft —Redmond, WA
- $102,100 - $219,200 a year
- Full-time
- Computer science
- Azure
- Doctoral degree
11d
Applied Scientist
Adobe —Seattle, WA
- $120,700 - $238,600 a year
- Full-time
- Computer science
- Computer Science
- Master's degree
Applied Scientist, Amazon Connect Talent
Amazon Development Center U.S., Inc. —Seattle, WA
- $142,800 - $223,400 a year
- Full-time
- Computer Science
- System design
- Mid-level
- AD&D insurance
- Health insurance
Senior Applied Scientist
Microsoft —Redmond, WA
- $119,800 - $261,000 a year
- Full-time
- Background check
- Doctoral degree
- Computer Science
5d
Scientist I Biopreservation
Biolife Solutions, Inc. —Bothell, WA
- $109,593 - $158,910 a year
- Full-time
- Background check
- Bachelor of Science
- Pass drug screening
- Disability insurance
- Health insurance
Senior Applied Scientist, Trust & Safety
DAT —Seattle, WA
- $183,000 - $226,000 a year
- Hybrid work
- Computer Science
- 5 years
- Doctor of Philosophy
- Health savings account
- AD&D insurance
Sr Applied Scientist, Ring AI
Amazon.com LLC —Bellevue, WA
- $167,100 - $226,100 a year
- Full-time
- 6 years
- System design
- Java
- AD&D insurance
- Health insurance
Staff Applied Scientist
QXO —Seattle, WA
- $191,000 a year
- Full-time
- 7 years
- Computer Science
- SQL
- Paid training
- Health insurance
Applied Scientist II, Amazon, Amazon
Amazon.com Services LLC —Seattle, WA
- $142,800 - $222,200 a year
- Full-time
- Java
- Master's degree
- C++
- AD&D insurance
- Health insurance
Principal Applied Scientist
Microsoft —Redmond, WA
- $142,800 - $331,200 a year
- Full-time
- Hybrid work
- Doctoral degree
- Computer Science
- Office
Applied Scientist , Amazon Customer Service
Amazon.com Services LLC —Seattle, WA
- $136,000 - $184,000 a year
- Full-time
- Mid-level
- Java
- SQL
- AD&D insurance
- Health insurance
12d
Senior Applied Scientist
Outreach —Seattle, WA
- $140,000 - $175,000 a year
- Full-time
- Computer Science
- Java
- Master's degree
- Health insurance
- Dental insurance
Applied Scientist, Sync
Outreach —Seattle, WA
- $130,000 - $170,000 a year
- Full-time
- Computer Science
- Java
- Master's degree
- Health insurance
- Dental insurance
Applied Scientist, Ring AI
Amazon.com Services LLC —Bellevue, WA
- $142,800 - $193,200 a year
- Full-time
- System design
- Java
- Master's degree
- AD&D insurance
- Health insurance
Applied Scientist, Special Projects
Amazon.com Services LLC —Seattle, WA
- $142,800 - $193,200 a year
- Full-time
- Computer Science
- Java
- Doctor of Philosophy
- AD&D insurance
- Health insurance
Applied Scientist, RL post-training, AWS
Amazon.com Services LLC —Seattle, WA
- $142,800 - $193,200 a year
- Full-time
- Mid-level
- Java
- Master's degree
- AD&D insurance
- Health insurance
Applied Scientist II, Search Ranking
Amazon.com Services LLC —Seattle, WA
- $142,800 - $222,200 a year
- Full-time
- Office
- Java
- Master's degree
- AD&D insurance
- Health insurance

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Immunology Senior Research Scientist - Flow Cytometry

Vertex Pharmaceuticals -
Seattle, WA

Apply Now

Job Details

Full-time
$124,200 - $186,400 a year

Benefits

Loan repayment program
Dental insurance
Tuition reimbursement
Paid time off
Vision insurance
401(k) matching

Qualifications

Biology
Genomics
Immunological assays
Molecular Biology
Content creation for technical audiences
Molecular biomarkers
Clinical development
Technical documentation
Immunological laboratory techniques
Efficiency improvement
Design of experiments
R
Continuous improvement (laboratory quality control method)
Flow cytometers
Assay development
Cell Biology
Research project design
Master's degree
Implementing laboratory quality control protocols
Collaborative research
Analysis skills
Bachelor's degree
Blood sample handling
Doctor of Philosophy
Scientific protocols
Decision making
Mentoring
Organizational skills
Data-driven problem-solving
Staining (laboratory technique)

Full Job Description

Job Description

At Vertex, we invest in scientific innovation to create transformative medicines for people with serious diseases. Our growing Molecular Profiling team is seeking a Senior Scientist, Flow Cytometry to provide deep technical expertise in flow cytometry and cellular profiling to support discovery, translational, and development programs. This role will lead and drive the generation of high-dimensional insights into cell phenotype, function, and biology that help inform mechanism of action, biomarker strategies, patient stratification, and program decision-making.

The successful candidate will independently own cytometry workstreams across multiple programs and contribute to the scientific direction of molecular profiling efforts.

The ideal candidate is a highly motivated scientist with strong experience in multiparameter and high-dimensional flow cytometry (spectral flow), cell sorting, and immunophenotyping and a proven ability to thrive in a collaborative, fast-paced research environment.

Key Duties and Responsibilities

Design, develop, optimize, and execute flow cytometry-based assays to support research and translational objectives across discovery and development programs
Lead multicolor immunophenotyping panel design, including marker selection, fluorochrome strategy, controls, and advanced gating and data analysis approaches
Apply flow cytometry in conjunction with molecular profiling data to enable deeper characterization of cell states, pathway activity, target engagement, and disease-relevant biology
Partner with cross-functional teams to integrate cellular and molecular datasets, including transcriptomic, proteomic, and biomarker data, to support hypothesis generation and program strategy
Analyze and interpret complex flow cytometry data to support actionable biological insights, mechanism of action studies, and translational hypotheses
Establish and apply best practices for sample preparation, staining, acquisition, compensation, quality control, and data analysis
Troubleshoot technical issues and drive continuous improvement in assay robustness, reproducibility, and efficiency
Contribute to experimental design, study planning, and strategic program discussions and decision-making
Prepare technical documentation, protocols, study summaries, and presentations
Evaluate and implement emerging cytometry and profiling technologies, reagents, and workflows where appropriate
Mentor junior team members and serve as a scientific resource within the broader organization
Independently lead cytometry workstreams across multiple programs, ensuring alignment with program goals and timelines
Influence program decisions through data-driven insights and clear communication of complex biological findings

Knowledge and Skills

Deep expertise in flow cytometry principles, instrumentation, and assay development
Strong understanding of immune profiling, cellular phenotyping, and molecular profiling strategies
Experience connecting cell-based phenotypic data with broader molecular signatures and translational biomarkers
Experience designing and optimizing high-parameter or multicolor flow cytometry panels, including intracellular and phospho-flow analysis
Proficiency in flow cytometry analysis software such as FlowJo, Dotmatics or equivalent
Working knowledge of data analysis approaches and familiarity with R or Python-based workflows (preferred)
Strong scientific reasoning, data interpretation, and problem-solving skills
Ability to communicate complex technical findings clearly to technical and cross-functional stakeholders
Strong organizational skills and the ability to manage multiple priorities in a matrixed environment
Demonstrated ability to operate with a high degree of independence while contributing to team-based goals

Education and Experience

PhD in Immunology, Cell Biology, Molecular Biology, Biology, Biomedical Sciences, or related discipline with 2+ years of relevant experience; or
Master’s degree with 6+ years of relevant experience; or
Bachelor’s degree with 8+ years of relevant experience

Preferred Qualifications

Experience with primary human samples, including blood- or tissue-derived specimens
Familiarity with spectral flow cytometry and cell sorting (BD, Cytek, Sony platforms)
Experience working in environments where molecular profiling and cell-based assays are jointly used to answer translational questions
Experience in immunology and inflammation disease areas
Experience supporting translational research, biomarker strategies, or clinical development
Experience integrating cytometry data with single-cell genomics, spatial transcriptomics, or proteomics datasets

Pay Range:

$124,200 - $186,400

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]

Apply Now

Refine Your Search

applied scientist jobs in manchester, wa

Immunology Senior Research Scientist - Flow Cytometry

Immunology Senior Research Scientist - Single-Cell Genomics

Research Scientist

Applied Scientist

Applied Scientist

Applied Scientist, Amazon Connect Talent

Senior Applied Scientist

Scientist I Biopreservation

Senior Applied Scientist, Trust & Safety

Sr Applied Scientist, Ring AI

Staff Applied Scientist

Applied Scientist II, Amazon, Amazon

Principal Applied Scientist

Applied Scientist , Amazon Customer Service

Senior Applied Scientist

Applied Scientist, Sync

Applied Scientist, Ring AI

Applied Scientist, Special Projects

Applied Scientist, RL post-training, AWS

Applied Scientist II, Search Ranking

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