Top 15 Senior machine operator Jobs in Massachusetts

Sr. Associate, Serialization and Packaging
Replimune —Framingham, MA
- $103,500 - $133,500 a year
- Full-time
- Oracle
- Mid-level
- High school diploma or GED
Quick Apply
MACHINIST, SENIOR, EXPERIMENTAL, College of Arts & Sciences, Physics
Boston University —Boston, MA
- 5 years
- University
- Senior level
- Paid holidays
- Health insurance
Sr Machinist
MIT Lincoln Laboratory —Lexington, MA
- $44.63 - $48.65 an hour
- Extended hours
- Microsoft Outlook
- Word processing
- Ability to lift 50 pounds
- Health insurance
- Dental insurance
Sr CNC Machinist
Textron Systems —Wilmington, MA
- $67,900 - $101,300 a year
- Full-time
- CAD
- Continuous improvement
- Senior level
- Paid training
- Health savings account
SENIOR CNC MACHINIST
Accudynamics —Middleboro, MA
- Overtime
- 5 years
- Computer literacy
- ERP systems
CNC Machinist
Senior Metal Bellows Manufacturing —Sharon, MA
- $33 - $41 an hour
- Mid-level
- High school diploma or GED
- Continuous improvement
Quick Apply
Senior CNC Programmer & Machinist, 5-Axis
Rennscot —Woburn, MA
- $105,000 - $150,000 a year
- Full-time
- 5 years
- Engineering
- No experience needed
- Paid holidays
- Disability insurance
Electropolishing Technician
Senior Metal Bellows —Sharon, MA
- $22 - $28 an hour
- Full-time
- Computer literacy
- High school diploma or GED
- Computer skills
Quick Apply
Senior CNC Programmer & Machinist, 5-Axis
Rennscot MFG —Woburn, MA
- $105,000 - $150,000 a year
- Full-time
- 5 years
- Engineering
- No experience needed
Sr Production Operator
Avient —Holden, MA
- $25 - $28 an hour
- Online Application
- Ability to walk for extended periods
- Mid-level
- Forklift
Quick Apply
Senior Machinist
Vibram Corporation —North Brookfield, MA
- Schematics
- Ability to walk for extended periods
- 5 years
Quick Apply
Senior CNC Machinist
Alfa Laval —Newburyport, MA
- $28 - $38 an hour
- Overtime
- 5 years
- High school diploma or GED
- Ability to lift 50 pounds
- Wellness program
- Paid holidays
Heat-Treat Technician - 2nd Shift
Senior Metal Bellows —Sharon, MA
- $22 - $27 an hour
- Full-time
- Mid-level
- Computer skills
- Manufacturing
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Experienced Machinist - 2nd Shift
Senior Metal Bellows —Sharon, MA
- $32 - $41 an hour
- Full-time
- 5 years
- High school diploma or GED
- Continuous improvement
Quick Apply

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Sr. Associate, Serialization and Packaging

Replimune -
Framingham, MA

Quick Apply

Job Details

Full-time
$103,500 - $133,500 a year

Qualifications

Pharmaceutical manufacturing facility experience

Full Job Description

Overview

Replimune’s mission is to revolutionize cancer treatment with therapies designed to activate a powerful and durable full-body anti-tumor response, boldly transforming cancer care because patient’s lives depend on it.

At Replimune, we live by our values:

United: We Collaborate for a Common Goal.

Audacious: We Are Bold.

Dedicated: We Give Our Full Commitment.

Candid: We Are Honest With Each Other.

People are at the center of everything we do, and when it comes to our employees, we make it personal. With a deep sense of purpose, a strong and evolving culture, a competitive and forward-looking total rewards program, everyone at Replimune has a unique opportunity to impact on the lives of patients, caregivers and themselves.

Join us, as we reshape the future.

The Senior Associate, Serialization & Packaging is responsible for supporting the execution, coordination, and continuous improvement of commercial packaging and serialization operations at Replimune's Framingham facility. This role serves as a technical resource and subject matter expert for packaging line operations, serialization processes, and associated systems, including Antares serialization equipment, TraceLink serialization platforms, and Oracle transactions supporting commercial distribution.

Working closely with the Manager, Commercial Packaging & Serialization and Packaging team, this position supports daily packaging operations, batch execution, serialization activities, documentation review, training, troubleshooting, and operational readiness. The Senior Associate plays a critical role in ensuring products are packaged, serialized, documented, and transferred for distribution in compliance with cGMP, GDP, company procedures, and regulatory requirements.

The ideal candidate combines strong technical knowledge of packaging and serialization operations with hands-on execution experience in a commercial pharmaceutical or biotechnology environment.

Key Responsibilities:

Packaging & Serialization Operations

Support the execution of commercial packaging, labeling, and serialization activities conducted at Replimune's Framingham facility.
Perform setup, operation, line clearance, troubleshooting, and shutdown of packaging and serialization equipment.
Serve as the primary operational resource for serialization processes including commissioning, aggregation, reconciliation, and exception management.
Ensure packaging and serialization activities are executed in accordance with approved batch records, SOPs, and GMP requirements.
Monitor packaging line performance and identify opportunities to improve efficiency, throughput, and compliance.
Support product packaging activities through final shipment preparation and transfer to the 3PL.

Serialization Systems Support

Serve as the site subject matter expert for serialization operations and associated business processes.
Support operation and troubleshooting of Antares serialization equipment
Monitor and support TraceLink transaction processing, EPCIS data exchange activities, and serialization data integrity.
Execute and review Oracle transactions supporting packaging, inventory movements, and shipment activities.
Support testing, implementation, validation, and deployment of serialization system updates and enhancements.
Investigate and resolve serialization discrepancies, system exceptions, and operational issues.

Documentation, Compliance & Quality

Complete and review batch records, forms, logbooks, and serialization documentation in accordance with Good Documentation Practices (GDP).
Ensure all packaging and serialization documentation is accurate, complete, and inspection-ready.
Support deviation investigations, CAPAs, change controls, and quality events related to packaging and serialization operations.
Maintain compliance with cGMP, GDP, safety requirements, and internal procedures.
Assist with internal audits, regulatory inspections, and inspection readiness activities.

Technical Leadership & Continuous Improvement

Provide day-to-day guidance and technical support to Packaging Associates and other operational personnel.
Support onboarding and training of new employees on packaging and serialization processes, SOPs, and equipment.
Develop and maintain training materials, work instructions, and operational best practices.
Analyze operational metrics and process performance to identify improvement opportunities.
Lead or participate in continuous improvement initiatives focused on packaging operations, serialization compliance, equipment reliability, and operational efficiency.
Prepare technical reports, presentations, and operational summaries as required.

Additional Skills/Preferences:

Experience supporting commercial-stage pharmaceutical products.
Experience operating within an in-house packaging and serialization environment.
Experience with DSCSA compliance and serialization regulations.
Experience training and mentoring manufacturing or supply chain personnel.
Experience working with Antares serialization equipment or similar systems.
Experience using TraceLink or equivalent serialization management platforms.
Working knowledge of Oracle ERP transactions within operations environment
Strong understanding of cGMP, GDP, and Good Documentation Practices.

Educational requirements:

2–4 years of experience in a pharmaceutical, biotechnology, medical device, or other regulated GMP environment.
Associates Degree, Biotechnology Certificate, or Bachelor's Degree in Life Sciences, Engineering, Supply Chain, or related discipline preferred.
High School Diploma or GED with relevant pharmaceutical or biotechnology industry experience may be considered.

Replimune is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive. For this role, the anticipated base pay range is $103,500 - $133,500. The exact base pay offered for this role will depend on various factors, including but not limited to the candidate’s unique set of qualifications, skills, and experience. Our current organizational needs also play a part in determining your final offer.

About Replimune

Replimune Group, Inc., headquartered in Woburn, MA, was founded in 2015 with the mission to transform cancer treatment by pioneering the development of a novel portfolio of oncolytic immunotherapies. Replimune’s proprietary RPx platform is based on a potent HSV-1 backbone intended to maximize immunogenic cell death and the induction of a systemic anti-tumor immune response. The RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response. The RPx product candidates are expected to be synergistic with most established and experimental cancer treatment modalities, leading to the versatility to be developed alone or combined with a variety of other treatment options. For more information, please visit www.replimune.com.

We are an Equal Opportunity Employer.

Quick Apply

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senior machine operator jobs in massachusetts

Sr. Associate, Serialization and Packaging

MACHINIST, SENIOR, EXPERIMENTAL, College of Arts & Sciences, Physics

Sr Machinist

Sr CNC Machinist

SENIOR CNC MACHINIST

CNC Machinist

Senior CNC Programmer & Machinist, 5-Axis

Electropolishing Technician

Senior CNC Programmer & Machinist, 5-Axis

Sr Production Operator

Senior Machinist

Senior CNC Machinist

Heat-Treat Technician - 2nd Shift

Experienced Machinist - 2nd Shift

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