Top 79 Chemist Jobs in Milpitas Ca

Senior/Principal Scientist, Peptide Medicinal Chemistry
Stealth Biotech —San Mateo, CA
- $150,000 - $200,000 a year
- Full-time
- Analysis skills
- Doctor of Philosophy
- In-person
- Health insurance
- Dental insurance
Quick Apply
Continuum Multiphysics Modeling Research Positions for Materials and Processing at NASA Ames
NASA Ames Research Center —Mountain View, CA
- $75,000 - $140,000 a year
- Full-time
- Doctoral degree
- Math
- US work authorization
Quick Apply
Chemistry Lab Analyst (ICP-MS)
Ascend Clinical —Sunnyvale, CA
- $30 - $32 an hour
- Full-time
- Mid-level
- Math
- Cleaning
- Paid holidays
- Disability insurance
Quick Apply
Laboratory Chemist III
PENTAGON TECHNOLOGIES GROUP INC —Hayward, CA
- $34 - $38 an hour
- Full-time
- 3 years
- Bachelor's degree
- Senior level
- AD&D insurance
- Disability insurance
Quick Apply
2d
Chemist
4C Air —Sunnyvale, CA
- Email
- Research
- Mid-level
- Bachelor's degree
IN-ORGANIC CHEMIST
Torrent Laboratory —Milpitas, CA
- Email
- Bachelor of Science
- Analysis skills
- Bachelor's degree
- Health insurance
- Dental insurance
Quality Control Biochemist
Gator Bio —Palo Alto, CA
- $33 - $35 an hour
- Temporary
- Microsoft Excel
- Bachelor of Science
- Bachelor's degree
Quick Apply
5d
RESEARCH SCIENTIST
Department of Toxic Substances Control —Alameda County, CA
- $6,942 - $9,799 a month
- Multiple hires
- Mid-level
- US work authorization
3d
Quality Control Analytical Chemist
Medterials, Inc. —San Carlos, CA
- $100,000 - $150,000 a year
- Overtime
- Microsoft Word
- Microsoft Excel
- Bachelor of Science
- Health insurance
- Dental insurance
Quick Apply
11d
Nanoparticle Chemistry
NVIGEN —Sunnyvale, CA
- Bachelor of Science
- Research
- Mid-level
Staff Scientist II - Medicinal Chemistry
Protagonist Therapeutics —Newark, CA
- $135,000 - $145,000 a year
- Full-time
- Doctor of Philosophy
- Pediatrics
- Organizational skills
Quick Apply
Scientist I, QC Technical Resources
Nova Pneuma Inc —Fremont, CA
- From $120,000 a year
- Word processing
- Bachelor of Science
- Bachelor's degree
- Health insurance
Quick Apply
Analytical Chemist
Oryx Advanced Materials Inc —Fremont, CA
- $40 - $50 an hour
- Full-time
- Bachelor of Science
- 3 years
- Analysis skills
- Health insurance
- Dental insurance
Quick Apply
Field Chemist I
Republic Services —San Jose, CA
- $31.70 - $43.62 an hour
- 8 hour shift
- Inventory management
- Driver's License
- Bachelor's degree
- AD&D insurance
- Employee stock purchase plan
12d
Chemist 1 New College Grad (Bachelor's - Santa Clara, CA)
Applied Materials —Santa Clara, CA
- Full-time
- Bachelor's degree
- Leadership
- Entry level
Senior Scientist, Bioanalytical Development
Protagonist Therapeutics —Newark, CA
- $140,000 - $160,000 a year
- Full-time
- 5 years
- Bachelor of Science
- Bachelor's degree
- Wellness program
- Commuter assistance
Quick Apply
14d
Quality Control Analytical Chemist
MEDTERIALS INC —San Carlos, CA
- $100,000 - $150,000 a year
- Overtime
- Microsoft Excel
- Bachelor of Science
- No experience needed
- Health insurance
- Dental insurance
Quick Apply
11d
Scientist, Organic Chemistry
Kodiak Sciences Inc. —Palo Alto, CA
- Full-time
- Doctor of Philosophy
- Senior level
- Communication skills
QC Analyst II
Nova Pneuma, Inc. —Fremont, CA
- From $41 an hour
- Microsoft Word
- Mid-level
- Master's degree
- Health insurance
Quick Apply
Research Associate, Quality Operations
Kodiak Sciences Inc. —Palo Alto, CA
- Bachelor of Science
- Research
- Mid-level

I want to receive the latest job alert for chemist in milpitas ca

By signing in to your account, you agree to SimplyHired's Terms of Service and consent to our Cookie and Privacy Policy.

Explore jobs in more locations

chemist jobs near milpitas ca

Senior/Principal Scientist, Peptide Medicinal Chemistry

Stealth Biotech
San Mateo, CA

Quick Apply

Job Details

Full-time
$150,000 - $200,000 a year

Benefits

Health insurance
Dental insurance
401(k)
Vision insurance

Qualifications

AI models
Project team coordination
Computational research
Teamwork
Automation
High-performance liquid chromatographs
Medicinal chemistry
Doctor of Philosophy
Pharmaceutical analysis
Project delivery management
Leading team collaboration initiatives
Chemistry
Research data analysis
Cross-functional team management
Pharmaceutical research experience
Python
Cross-functional communication
Nuclear magnetic resonance (NMR) spectroscopy
Mass spectrometry
Molecular analysis

Full Job Description

The role

The candidate will lead peptide medicinal chemistry on one or more discovery programs, from hit triage and affinity maturation through developability optimization to candidate selection.

The role carries end-to-end responsibility for the DMTA cycle: defining the design hypothesis, directing synthesis through contract research organizations, interpreting the resulting data, and returning it to the design models. It is a hands-on position that combines individual technical contributions with project leadership. Close collaboration with our AI team is central to the role: translating model output into designs that can be made and tested, returning experimental results in a form the models can learn from, and helping shape what the models are asked to predict next.

Key responsibilities

Design and program leadership

Set and defend the medicinal chemistry strategy for assigned peptide programs, from hits to development candidates.
Drive affinity maturation campaigns.
Optimize developability alongside potency: proteolytic stability, solubility, permeability, half-life extension, and route-of-administration constraints.
Design off-target examination strategies in collaboration with biology and DMPK.
Represent chemistry in portfolio reviews and before the leadership team, with clear go/no-go recommendations and the data supporting them.

DMTA execution, automation, and throughput

Run a high-cadence DMTA cycle: design molecules, prioritize what gets made, and reduce the time from hypothesis to result.
Establish the data discipline that makes the cycle learnable — structured capture of sequences, structures, assay results, and decisions; and feedback to models.

CRO and external management

Own the relationship with peptide synthesis and analytical CROs.
Prepare and review synthesis requests and characterization data.

Working with the platform

Partner with machine-learning colleagues.
Curate the chemistry knowledge on which the platform depends.

Requirements

PhD in organic chemistry, medicinal chemistry, biochemistry, or a closely related field.
Extensive experience in peptide medicinal chemistry within a drug discovery setting, including demonstrated success in affinity maturation and in optimizing ADME and developability properties of peptides.
Strong synthetic and analytical chemistry skills: solid-phase and solution-phase peptide synthesis, macrocyclization chemistries, non-natural and modified building blocks, conjugation, and the analytical methods required to characterize the products (LC-MS, HRMS, NMR, prep-HPLC, chiral and purity analysis).
Experience in a project-leading role — a discovery project or workstream led end to end, with accountability for direction, cross-functional coordination, and outcomes.
High-throughput and automation experience applied to the DMTA cycle — parallel synthesis, high-throughput analytics, and associated data handling.
Fluency in structure-based and property-based design.
Clear scientific communication, both written and verbal, across chemistry, biology, and computational audiences.

Desirable

Working knowledge of agentic workflows.
Experience establishing synthetic and assay workflows from scratch.
Familiarity with computational tools: docking, molecular dynamics, structure prediction, cheminformatics, or scripting in Python.
Experience with peptide half-life extension strategies or with oral peptide delivery.
Track record in a relevant modality — macrocyclic peptides, constrained peptides, peptide–drug conjugates, etc.
Experience taking a peptide program through IND-enabling studies or working with CMC and process chemistry colleagues on scale-up.
Publications, granted patents, or a preclinical or clinical asset you can speak to.

What we offer

Ownership over the chemistry strategy of a young portfolio, and influence over the design platform itself.
A short path from decision to experiment — a small team, short decision paths, and direct access to leadership.
Close, day-to-day exposure to computational and machine-learning approaches to molecular design.
Competitive salary, early-stage equity, and a full benefits package.

About us

We are an early-stage biotechnology company currently in stealth mode. We have developed proprietary machine-learning models and are applying them to our peptide therapeutics pipeline.

Pay: $150,000.00 - $200,000.00 per year

Benefits:

401(k)
Dental insurance
Health insurance
Vision insurance

Work Location: In person

Quick Apply

Refine Your Search

chemist jobs in milpitas ca

Senior/Principal Scientist, Peptide Medicinal Chemistry

Continuum Multiphysics Modeling Research Positions for Materials and Processing at NASA Ames

Chemistry Lab Analyst (ICP-MS)

Laboratory Chemist III

Chemist

IN-ORGANIC CHEMIST

Quality Control Biochemist

RESEARCH SCIENTIST

Quality Control Analytical Chemist

Nanoparticle Chemistry

Staff Scientist II - Medicinal Chemistry

Scientist I, QC Technical Resources

Analytical Chemist

Field Chemist I

Chemist 1 New College Grad (Bachelor's - Santa Clara, CA)

Senior Scientist, Bioanalytical Development

Quality Control Analytical Chemist

Scientist, Organic Chemistry

QC Analyst II

Research Associate, Quality Operations

I want to receive the latest job alert for chemist in milpitas ca

Explore jobs in more locations

Job Seeker Tools

Employer Tools

Browse

Stay Connected