Top 15 Principal scientist Jobs in Minnesota

Principal Clinical Scientist
Beckman Coulter Diagnostics —Chaska, MN
- $120,000 - $165,000 a year
- Full-time
- Doctoral degree
- Master's degree
- Bachelor's degree
- Health insurance
- Dental insurance
Principal Scientist, Microbiology
The U.S. Pharmacopeia (USP) —Saint Paul, MN
- $138,123 - $173,900 a year
- Full-time
- 11+ years
- Doctor of Philosophy
- Mentoring
- Paid time off
Principal Clinical Scientist (Neurodegenerative)
Beckman Coulter Diagnostics —Chaska, MN
- $120,000 - $130,000 a year
- Full-time
- Doctoral degree
- Master's degree
- Bachelor's degree
- Health insurance
- Dental insurance
10d
Associate Principal Product Guidance Scientist - Pet
General Mills —Minneapolis, MN
- $110,800 - $166,300 a year
- Full-time
- 7 years
- Doctor of Philosophy
- Psychology
- Health insurance
11d
Principal Scientist
Galois, Inc. —Minneapolis, MN
- Full-time
- Hybrid work
- Computer Science
- Office
- Math
- Paid parental leave
- Health savings account
Quick Apply
Principal Clinical Quality Assurance Specialist
Boston Scientific —Maple Grove, MN
- $116,600 - $221,500 a year
- Hybrid work
- 5 years
- Engineering
- Office
Principal Reimbursement Analyst
Medtronic —Minneapolis, MN
- $138,400 - $207,600 a year
- Full-time
- Remote
- 7 years
- Analysis skills
- Bachelor's degree
- Health savings account
- Employee stock purchase plan
Clinical Research Physician (Principal Investigator/Sub-Investigator) - Full Time
Thermo Fisher Scientific —Richfield, MN
- $240,000 - $315,000 a year
- Full-time
- Background check
- Medicine
- Pass drug screening
- Commuter assistance
- Paid parental leave
Archaeological Principal Investigator
WESTWOOD PROFESSIONAL SERVICES INC —Minnetonka, MN
- $70,000 - $90,000 a year
- Full-time
- Management
- 5 years
- Office
Principal AI Computer Vision Engineer
Medtronic —Fridley, MN
- $160,800 - $241,200 a year
- Full-time
- Research
- Office
- 3 years
- Health savings account
- Employee stock purchase plan
1d
Part-Time Physician | Principal Investigator
Razi Research Partners —Minneapolis, MN
- $50,000 - $100,000 a year
- Contract
- Medicine
- BC/BE
- Clinic
Quick Apply
14d
Principal Investigator
Denali Health —Minneapolis, MN
- Hybrid work
- Medicine
- BC/BE
- Doctor of Philosophy
Quick Apply
23h
Principal Toxicologist
Altria —United States
- $119,600 - $173,450 a year
- 5 years
- Analysis skills
- Presentation skills
- Profit sharing
- Paid parental leave

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Principal Scientist, Microbiology
The U.S. Pharmacopeia (USP) —Saint Paul, MN
Ph.D. degree in Microbiology, Cell Biology, Biochemistry or a relevant field with 12+ years of experience in the microbiology field;
$138,123 - $173,900 a year
Principal Clinical Scientist (Neurodegenerative)
Beckman Coulter Diagnostics —Chaska, MN
Act as a scientific and clinical liaison with regulatory bodies, key opinion leaders, and external sites to develop protocols, claims, and evidence plans.
$120,000 - $130,000 a year
10d

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Principal Food Scientist
Schwan's Company —Gahanna, OH
Apply food science expertise to develop, improve, and optimize products, ingredients, processes, packaging, and preservation methods while ensuring quality,…
$107,000 - $178,000 a year
Quick Apply
5d
Principal Toxicologist
Altria —United States
The selected candidate will use their scientific and technical expertise in preclinical toxicology to conduct toxicological studies in the support of reduced-…
$119,600 - $173,450 a year

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Principal Clinical Scientist

Beckman Coulter Diagnostics -
Chaska, MN

Apply Now

Job Details

Full-time
$120,000 - $165,000 a year

Benefits

Health insurance
Dental insurance
401(k)
Paid time off
Vision insurance

Qualifications

Research project design
Data interpretation
Project stakeholder communication
Cross-functional communication

Full Job Description

At Danaher Diagnostics, we are passionate about improving health care through fast, accurate diagnostic testing. Our mission drives us, every moment of every day, as we develop scalable, groundbreaking solutions to solve the world’s most complex health challenges. Our associates are involved in every stage of diagnostics, from ideation to development and delivery of testing advancements that improve patient outcomes across a range of settings. As a member of our team, you can make an immediate, measurable impact on a global scale, within an environment that fosters career growth and development.

Danaher Diagnostics is a community of six companies. Together, we’re working at the pace of change on diagnostic tools that address the world’s biggest health challenges, driven by knowing that behind every test there is a patient waiting.

Learn about the Danaher Business System which makes everything possible.

Principal Clinical Scientist. This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter Diagnostics and Life Sciences, operating companies of Danaher Diagnostics. You will drive strategic study designs, ensuring regulatory compliance, and achieving key milestones for critical clinical studies in these vital markets.

This position is part of the Danaher Diagnostics, Beckman Coulter Inc. organization and will be located on-site at either Chaska, MN or Miami, FL. At Danaher Diagnostics, our vision is to be the leading provider of seamlessly connected diagnostic solutions.

In this role, you will have the opportunity to:

Design clinical studies and evidence strategies supporting global regulatory submissions (e.g., FDA 510(k)/PMA, CE‑IVDR) across multiple diagnostic modalities.
Act as a scientific and clinical liaison with regulatory bodies, key opinion leaders, and external sites to develop protocols, claims, and evidence plans.
Partner cross‑functionally with R&D, Regulatory, Medical Affairs, Quality, and Commercial teams to align clinical programs with product development and market access needs.
Author and review clinical and regulatory documentation—including study reports, technical files, and publications—to support product clearance and commercialization.
Build strong internal and external collaborations, mentor junior scientists, and maintain expertise in evolving regulatory standards, clinical guidelines, and diagnostic technologies.

The essential requirements of the job include:

Bachelor’s degree in Life Sciences, Healthcare, or a related field with 9+ years of experience in clinical research, specifically with significant experience in US and/or EU trials, or a Master’s degree with 12+ years of experience or Doctoral degree with 4+ years of same experience.
In-depth understanding of clinical study design and methodology in the diagnostics, medical device, or pharmaceutical industry with products intended for the US and EU markets.
Demonstrated ability to identify and solve complex issues in clinical trial conduct and scientific interpretation.
Ability to critically review and interpret scientific and clinical trial data, and oversee the scientific aspects of study protocols and reports.
Excellent communication (written and verbal) and interpersonal skills for collaborating with cross-functional stakeholders.

It would be a plus if you also possess previous experience in:

Experience in study designs for diagnostic technologies (IVD) is highly preferred, specifically for Clinical Chemistry, Immunoassays, Hematology, Urinalysis, Flow Cytometry, and/or Biomarkers.
Advanced degree in Science, Healthcare, or Regulatory/Clinical Affairs.
Professional certification in Clinical Research (e.g., SoCRA, ACRP).

Danaher Diagnostics, a Danaher company, offers a broad array of comprehensive, competitive benefit programs that add value to our lives. Whether it’s a health care program or paid time off, our programs contribute to life beyond the job. Check out our benefits at danaherbenefitsinfo.com.

This job is also eligible for bonus/incentive pay.

Within Danaher Diagnostics we believe in designing a better, more sustainable workforce. We recognize the benefits of flexible, remote working arrangements for eligible roles and are committed to providing enriching careers, no matter the work arrangement. This position is eligible for a remote work arrangement in which you can work remotely from your home. Additional information about this remote work arrangement will be provided by your interview team. Explore the flexibility and challenge that working within Danaher Diagnostics can provide.

The annual salary range for this role is $120K-$165K. This is the range that we in good faith believe is the range of possible compensation for this role at the time of this posting. This range may be modified in the future.

This job is also eligible for bonus/incentive pay.

We offer comprehensive package of benefits including paid time off, medical/dental/vision insurance and 401(k) to eligible employees.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company’s sole discretion, consistent with the law.

Join our winning team today. Together, we’ll accelerate the real-life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.

For more information, visit www.danaher.com.

Apply Now

Refine Your Search

principal scientist jobs in minnesota

Principal Clinical Scientist

Principal Scientist, Microbiology

Principal Clinical Scientist (Neurodegenerative)

Associate Principal Product Guidance Scientist - Pet

Principal Scientist

Principal Clinical Quality Assurance Specialist

Principal Reimbursement Analyst

Clinical Research Physician (Principal Investigator/Sub-Investigator) - Full Time

Archaeological Principal Investigator

Principal AI Computer Vision Engineer

Part-Time Physician | Principal Investigator

Principal Investigator

Principal Toxicologist

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