Top 14 Senior building engineer Jobs in Oakland, Ca

Senior Maintenance, Reliability, and Calibration Engineer (GMP)
GeneFab —Alameda, CA
- $145,000 - $180,000 a year
- Full-time
- 6 years
- Senior level
- Electrical Engineering
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Senior Engineer - Building Enclosure
RDH Building Science Inc. USA —Oakland, CA
- $117,000 - $150,000 a year
- Full-time
- Hybrid work
- 6 years
- Engineering
- Continuous improvement
- Health insurance
- Dental insurance
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Senior Engineer, Facilities
Allogene Therapeutics —Newark, CA
- $135,000 - $160,000 a year
- Full-time
- US work authorization
- Organizational skills
- Experience equivalent to degree accepted
- Health insurance
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Sr Building Performance Engineer
HGA —San Francisco, CA
- $121,000 - $158,800 a year
- Full-time
- Management
- Bachelor of Science
- 11+ years
- Paid parental leave
- Disability insurance
Senior Nuclear Facility Engineer
Kairos Power —Alameda, CA
- $140,600 - $165,400 a year
- Extended hours
- Remote
- 5 years
- Office
- Analysis skills
- Commuter assistance
- Health insurance
Senior Plumbing Engineer
CMTA —Lafayette, CA
- $115,000 - $150,000 a year
- Full-time
- Hybrid work
- Schematics
- 5 years
- Research
- AD&D insurance
- Disability insurance
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Senior Electrical Engineer
CMTA —Lafayette, CA
- $135,000 - $220,000 a year
- Full-time
- Hybrid work
- Research
- Office
- US work authorization
- AD&D insurance
- Disability insurance
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Senior Electrical Engineer
AECOM —Oakland, CA
- $140,000 - $170,000 a year
- Full-time
- Hybrid work
- 6 years
- Bachelor of Science
- Office
- AD&D insurance
- Employee stock purchase plan
Senior Mechanical Engineer
CMTA —Lafayette, CA
- $150,000 - $190,000 a year
- Full-time
- Hybrid work
- Schematics
- System design
- Research
- AD&D insurance
- Disability insurance
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Senior Maintenance Engineer
US AMR-Jones Lang LaSalle Americas, Inc. —South San Francisco, CA
- $126,000 - $155,000 a year
- Online Application
- Background check
- Ability to lift 50 pounds
- US work authorization
- Paid parental leave
- Paid holidays
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14d
Senior Project Development Engineer (Federal) - CMTA Energy Solutions
CMTA —Lafayette, CA
- $100,000 - $150,000 a year
- Full-time
- 5 years
- Team management
- US work authorization
- AD&D insurance
- Disability insurance
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Senior Maintenance, Reliability, and Calibration Engineer (GMP)

GeneFab
Alameda, CA

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Job Details

Full-time
$145,000 - $180,000 a year

Qualifications

Quality control corrective actions
Equipment service recordkeeping
Incident investigation techniques for hazard identification
Defect resolution root cause analysis
Automation
Technical documentation
Preventive action implementation
Production deviation management
Facilities maintenance regulatory compliance
Quality control preventive actions
Corrective and preventive actions (CAPA)
FDA 21 CFR Part 11
GMP
Laboratory equipment calibration
Maintenance activity documentation
Manufacturing facility experience
Quality control documentation
Pharmaceutical company experience
Maintenance task scheduling
Compliance documentation
Automated systems
Regulatory/legal compliance standards in production
Quality standards in production
Biomedical regulatory compliance
Equipment testing
Technical Proficiency
Facilities maintenance schedule development
Quality control calibration
Failure analysis
Pharmaceutical manufacturing facility experience

Full Job Description

The Senior Maintenance, Reliability, and Calibration Engineer is responsible for driving asset performance, operational uptime, and regulatory compliance across all GMP manufacturing, packaging, and clean utility systems. This role serves as the site owner for calibration and maintenance programs—overseeing the planning, scheduling, and compliant execution of all technical work. The ideal candidate will combine deep reliability engineering expertise with hands-on mastery of metrology and maintenance management systems to ensure the facility consistently operates within its validated state.

Key Responsibilities:

Program Planning & Execution: Own the end-to-end lifecycle of the site’s Preventative Maintenance (PM) and Calibration programs. Lead the maintenance planning and scheduling workflow to ensure zero disruption to production schedules while maximizing technical team efficiency.

Metrology & Calibration Ownership: Define calibration requirements, tolerances, and loop checks for all process instrumentation and critical utilities. Manage the site calibration schedule, analyze instrument drift data to optimize calibration frequencies, and resolve out-of-tolerance (OOT) investigations.

Reliability & Validated State Maintenance: Develop and optimize maintenance strategies for critical process equipment (bioreactors, purification columns, filling lines) and clean utilities (WFI, purified water, clean steam, GMP HVAC) without compromising validated boundaries.

Deviation & CAPA Ownership: Lead technical investigations for equipment-related deviations, non-conformances, and OOT events. Utilize formal Root Cause Analysis (RCA) methodologies to implement robust Corrective and Preventive Actions (CAPAs).

Quality Change Control: Author, review, and execute Quality Change Controls for equipment modifications, optimization projects, or component obsolescence, ensuring zero negative impact on product quality or regulatory compliance.

CMMS & Data Integrity Management: Act as a key business owner for the Computerized Maintenance Management System (CMMS). Ensure all maintenance and calibration data, logs, asset histories, and electronic signatures strictly adhere to ALCOA+ data integrity principles and 21 CFR Part 11.

Audit Readiness & Vendor Management: Serve as the Subject Matter Expert (SME) for calibration and maintenance programs during regulatory inspections (FDA, EMA) and internal quality audits. Oversee specialized GMP service contractors, ensuring their documentation and execution meet site quality standards.

Spare Parts Strategy: Establish a risk-based GMP spare parts strategy, aligning critical spares with equipment criticality assessments to minimize stockouts of long-lead maintenance and calibration components.

Required Qualifications & Skills

Education: Bachelor’s degree in Mechanical, Electrical, Chemical, or Bioengineering, or a related technical discipline.

Experience: 6+ years of engineering experience in a highly regulated manufacturing environment, with at least 3-4 years directly within a GMP biopharmaceutical, medical device, or life sciences facility.

Calibration & Planning Expertise: Proven track record managing instrument calibration programs, loop testing, and metrology standards. Direct experience leading maintenance planning/scheduling functions.

Regulatory Knowledge: Strong working knowledge of 21 CFR Part 11, Part 210/211, and EU Annex 1 regulations, specifically regarding calibration tolerances and instrument impact assessments.

Technical Expertise: Deep familiarity with clean utilities and processing equipment, including a strong understanding of sanitary design principles and automated control systems (DeltaV, PLC).

Quality Systems: Proven experience authoring and managing Deviations, RCAs, CAPAs, and Change Controls within automated quality management systems (e.g., TrackWise, Veeva).

CMMS Proficiency: Advanced proficiency with validated CMMS platforms (specifically Blue Mountain RAM, Maximo, or SAP) for managing compliant asset histories, PMs, and calibration work orders.

Preferred Skills & Qualifications

Certified Maintenance & Reliability Professional (CMRP) or Certified Reliability Engineer (CRE) designation.

Experience in a commercial-scale Cell & Gene Therapy or Biologics facility.

Six Sigma Green or Black Belt certification.

About GeneFab

GeneFab is a contract manufacturing and synthetic biology biofoundry focused on cell and gene therapies. GeneFab was formed in 2023 with a vision to combine industry leading expertise in synthetic biology with advanced cGMP capabilities in order to accelerate the development and commercialization of genetic medicines. GeneFab offers its customers an extensive technology platform and know-how that spans early stage product design, technical development, and cGMP compliant production. GeneFab's technology platform includes bioinformatic-guided discovery of cell type promoters, directed evolution of small molecule-regulated gene switches, and the engineering of highly sensitive kill switches for enhanced safety and control of cellular therapies.

We are committed to an inclusive and diverse GeneFab. We believe that different perspectives lead to better ideas, and better ideas allow us to better understand the needs and interests of our diverse GeneFab team. We welcome people of different backgrounds, experiences, abilities, and perspectives and are an equal opportunity employer.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

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senior building engineer jobs in oakland, ca

Senior Maintenance, Reliability, and Calibration Engineer (GMP)

Senior Engineer - Building Enclosure

Senior Engineer, Facilities

Sr Building Performance Engineer

Senior Nuclear Facility Engineer

Senior Plumbing Engineer

Senior Electrical Engineer

Senior Electrical Engineer

Senior Mechanical Engineer

Senior Maintenance Engineer

Senior Project Development Engineer (Federal) - CMTA Energy Solutions

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