At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Let’s do this. Let’s change the world. Amgen is committed to transforming the lives of patients by advancing science, delivering innovative medicines, and creating sustainable value for healthcare systems worldwide. Obesity represents one of the most pressing global health challenges of our time, with rapidly evolving science, treatment paradigms, competitive dynamics, access considerations, and patient needs shaping the future of care.
To support this important therapeutic area, we are seeking a Senior Director, Global Forecasting, Obesity to lead forecasting strategy and execution for Amgen’s global obesity portfolio. This leader will be responsible for developing robust, evidence-based forecasts that inform portfolio strategy, investment decisions, launch planning, lifecycle management, resource allocation, and long-range business planning.
The Senior Director will partner closely with Global Commercial, U.S. Commercial, Regional Commercial, Finance, Medical, Market Access, R&D, Business Development, Market Research, Analytics, and Competitive Intelligence teams to ensure forecasts reflect aligned assumptions, rigorous methodology, and a forward-looking view of market evolution. The role requires a strategic forecasting leader who can operate in ambiguity, influence senior stakeholders, build organizational confidence in forecast outputs, and translate complex market dynamics into clear business implications.
This role requires at least 3 days on campus in Thousand Oaks, CA.
Global Forecasting Leadership
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Lead global forecasting for Amgen’s obesity portfolio, including pipeline assets, launch brands, lifecycle opportunities, and long-range therapeutic area planning.
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Develop and maintain short-term, mid-term, and long-range forecasts that support strategic planning, investment decisions, portfolio prioritization, and performance expectations.
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Establish clear forecasting frameworks, methodologies, governance, and assumptions across global, regional, and U.S. stakeholders.
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Translate forecast outputs into actionable strategic recommendations for senior leadership.
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Serve as a trusted forecasting advisor to Global Commercial, Finance, R&D, Medical, Market Access, and regional leadership teams.
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Ensure forecasts are credible, transparent, and grounded in robust data, business logic, and cross-functional alignment.
Obesity Market and Portfolio Forecasting
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Build forecasts that reflect the complexity of the global obesity market, including treatment adoption, patient flow, diagnosis and treatment rates, payer dynamics, adherence, persistence, capacity constraints, competitor entry, and evolving standards of care.
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Incorporate global and local market dynamics, including epidemiology, pricing and reimbursement, access restrictions, regional launch sequencing, promotional investment, and healthcare system differences.
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Evaluate key forecast drivers such as patient segmentation, demand generation, product profile, differentiation, market expansion, switching, discontinuation, and competitive response.
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Develop scenarios to assess upside and downside risks across major markets and regions.
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Partner with cross-functional teams to assess commercial implications of clinical data, label scenarios, indication expansion, device or formulation changes, and lifecycle opportunities.
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Support business development, licensing, and external innovation assessments as needed through objective commercial forecasting.
Strategic Planning and Decision Support
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Ensure forecasts directly inform global brand strategy, launch planning, annual operating plans, long-range planning, portfolio reviews, and investment trade-off decisions.
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Partner with Finance to align forecast outputs with financial planning cycles, revenue expectations, and business performance management.
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Collaborate with Market Access and Pricing teams to reflect reimbursement scenarios, access timing, net price assumptions, payer restrictions, and affordability considerations.
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Partner with Market Research, Analytics, and Competitive Intelligence to ensure forecasts are informed by the best available evidence and updated as new insights emerge.
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Develop clear narratives that explain forecast movement, key assumptions, risks, sensitivities, and strategic implications.
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Prepare executive-ready materials for senior leadership discussions, governance forums, portfolio reviews, and business planning meetings.
Forecast Governance and Excellence
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Lead cross-functional forecast alignment processes across global, regional, and U.S. teams.
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Ensure seamless forecast transitions from global strategy to regional and U.S. execution, with consistent assumptions, transparent methodology, and clear ownership.
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Drive forecast quality through disciplined model design, assumption documentation, sensitivity analysis, version control, and governance.
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Establish best practices for obesity forecasting, including launch curve development, analog selection, patient-based modeling, scenario planning, and competitive event modeling.
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Identify opportunities to enhance forecasting capabilities through advanced analytics, automation, real-world evidence, and improved data integration.
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Maintain a clear view of forecast risks and opportunities, proactively advising leadership on changes in market outlook.
Cross-Functional and Global Collaboration
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Partner with Global General Managers, regional commercial leaders, U.S. leadership, Finance, R&D, Medical, Market Access, Supply, Manufacturing, and Strategy teams to align around forecast assumptions and business implications.
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Influence senior stakeholders in a highly matrixed global organization.
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Facilitate productive debate around key assumptions while driving alignment and decision-making.
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Ensure global forecasts reflect local market realities while maintaining enterprise-level consistency.
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Build strong relationships across functions to ensure forecasting is embedded into strategic decision-making, not treated as a standalone exercise.
People Leadership
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Lead, develop, and mentor forecasting talent supporting the obesity portfolio.
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Foster a culture of analytical rigor, transparency, accountability, curiosity, and business partnership.
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Champion diversity, equity, and inclusion within the team and across forecasting processes.
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Build forecasting capability across the organization by coaching teams on methodology, assumptions, scenario planning, and interpretation of forecast outputs.
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Encourage innovation while maintaining disciplined forecasting standards.
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a collaborative leader with these qualifications.
Basic Qualifications:
Doctorate degree and 5 years of experience in forecasting, analytics, market insights, finance, strategy, or commercial planning
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Master’s degree and 9 years of experience in forecasting, analytics, market insights, finance, strategy, or commercial planning
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Bachelor’s degree and 11 years of experience in forecasting, analytics, market insights, finance, strategy, or commercial planning
In addition to meeting at least one of the above requirements, you must have at least 5 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above
Preferred Qualifications:
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Deep biopharmaceutical forecasting expertise, ideally with experience in obesity, metabolic disease, diabetes, cardiovascular disease, or other large primary care or specialty markets.
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Strong understanding of global pharmaceutical markets, including launch dynamics, pricing and reimbursement, market access, regional variation, and competitive strategy.
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Experience developing patient-based forecasts, epidemiology-driven models, analog-based launch forecasts, scenario analyses, and long-range portfolio forecasts.
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Ability to integrate inputs from market research, secondary analytics, competitive intelligence, clinical development, medical, access, and finance into cohesive forecast recommendations.
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Strong executive communication skills, with the ability to distill complex models and assumptions into clear strategic narratives.
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Proven ability to challenge assumptions constructively, manage ambiguity, and make sound recommendations with incomplete information.
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Experience supporting major investment decisions, launch planning, lifecycle planning, business development assessments, or portfolio prioritization.
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Strong business acumen and ability to connect forecast implications to strategy, resource allocation, and enterprise value.
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High adaptability and comfort operating in a fast-moving therapeutic area with rapidly evolving competitive dynamics.
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
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A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
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A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
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Stock-based long-term incentives
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Award-winning time-off plans
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Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
