Top 228 Sr. scientist, bioinformatics Jobs in Pennsylvania

Sr. Scientist
Legend Biotech US —Philadelphia, PA
- $127,313 - $167,099 a year
- Full-time
- Doctor of Philosophy
- US work authorization
- Senior level
Senior Scientist, Biology-Discovery
Merck —West Point, PA
- $117,000 - $184,200 a year
- Full-time
- Analysis skills
- Doctor of Philosophy
- Fair chance
- Paid holidays
- Health insurance
9d
Sr. Scientist; Bioinformatic and Translational Science
Fore Biotherapeutics US Inc —Philadelphia, PA
- $130,000 - $160,000 a year
- Full-time
- Remote
- Azure
- 3 years
- Master's degree
Research Data Scientist - Molecular and Precision Medicine / Medicine
Penn State University —University Park, PA
- $91,488 - $137,280 a year
- Online Application
- Background check
- 6 years
- Computer Science
- Paid holidays
- Health insurance
Sr. Scientist, Toxicology
Legend Biotech US —Philadelphia, PA
- $127,313 - $167,099 a year
- Full-time
- 5 years
- Doctor of Philosophy
- US work authorization
John Otto Haas Molecular Ecologist; Morris Arboretum & Gardens
University of Pennsylvania —Philadelphia, PA
- $67,155 - $95,000 a year
- Full-time
- Background check
- Mid-level
- Analysis skills
- Health insurance
- Dental insurance
Bioinformatics Engineer
WINDBER RESEARCH INSTITUTE —Windber, PA
- Full-time
- Computer Science
- Windows
- Master's degree
Senior Scientist, Chemistry
Merck —West Point, PA
- $117,000 - $184,200 a year
- Full-time
- Bachelor of Science
- Analysis skills
- Bachelor's degree
- Paid holidays
- Health insurance
Data Analyst (Department of Radiology)
University of Pennsylvania —Philadelphia, PA
- $62,067 - $80,000 a year
- Full-time
- Background check
- Computer Science
- Mid-level
- Health insurance
- Dental insurance
Bioinformatician A/B
University of Pennsylvania —Philadelphia, PA
- $57,500.00 - $101,200.50 a year
- Full-time
- Background check
- Mid-level
- 3 years
- Health insurance
- Dental insurance
Bioinformatician A
University of Pennsylvania —Philadelphia, PA
- $57,500 - $77,716 a year
- Full-time
- Background check
- Bachelor of Science
- Mid-level
- Health insurance
- Dental insurance
Sr. Scientist I LCMS
Resolian —Malvern, PA
- Full-time
- 5 years
- Bachelor of Science
- Bachelor's degree
1d
Computational Biologist
Thomas Jefferson University and Hospitals —Philadelphia, PA
- Full-time
- Computer Science
- Mid-level
- 3 years
- AD&D insurance
- Disability insurance
Scientist/Sr. Scientist/Principal Scientist
Frontage Laboratories —Exton, PA
- Full-time
- Continuous improvement
- Doctor of Philosophy
- Mentoring
- Disability insurance
- Health insurance
Quick Apply
12d
Senior Scientist, Reagent Technical Development and Operations (On-site)
Merck —West Point, PA
- $117,000 - $184,200 a year
- Full-time
- 3 years
- Analysis skills
- Bachelor's degree
- Paid holidays
- Health insurance
Manager of Genomics Core
Penn State University —University Park, PA
- $65,508 - $108,444 a year
- Online Application
- Background check
- Data analysis skills
- Master's degree
- Paid holidays
- Health insurance
Molecular Biology Scientist/Senior Associate Scientist
Legend Biotech US —Philadelphia, PA
- $93,463 - $122,670 a year
- Full-time
- Analysis skills
- Doctor of Philosophy
- Quality control
Quick Apply
Bioinformatics Engineer – Software Development - PHP (Remote)
Quest Diagnostics —Norristown, PA
- Full-time
- Remote
- Computer science
- Computer Science
- Mid-level
Quick Apply
8d
Senior Scientist, Computational Safety & Exploratory Pharmacology
Merck —West Point, PA
- $106,200 - $167,200 a year
- Full-time
- Analysis skills
- Bachelor's degree
- Doctor of Philosophy
- Paid holidays
- Health insurance
Postdoctoral Scholar - Public Health Sciences
Penn State University —University Park, PA
- Online Application
- Background check
- Computer Science
- University

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sr. scientist, bioinformatics jobs near pennsylvania

Sr. Scientist

Legend Biotech US -
Philadelphia, PA

Apply Now

Job Details

Full-time
$127,313 - $167,099 a year

Qualifications

Immunological assays
Biology research
Immunological laboratory techniques
Assay development
Doctor of Philosophy
Journal articles
Achieving project delivery timelines
Molecular analysis

Full Job Description

Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases. From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting-edge therapies for patients worldwide.

Legend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI® (ciltacabtagene autoleucel; cilta-cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma.

Legend Biotech is seeking a Sr. Scientist as part of the Research & Development team based in Philadelphia, Pennsylvania.

Role Overview

We are seeking an initiative-taking and creative scientist to grow our pipeline efforts. The candidate will be part of Legend Biotech, a leading cell therapy company with a commercial CAR drug product CARVYKTI and an attractive pipeline portfolio. The candidate will be an integral part of our Philadelphia R&D team, whose aim is to research, develop and advance the next generation of cell therapies using innovative in vivo delivery technologies and create novel CAR therapy to treat a wide range of cancer and autoimmune disease indications. This position will focus on in-vivo CAR. The position requires enthusiasm, passion, outstanding skills in the art, diligence, and a desire to create new medicines for patients.

Expertise in immunology and/or oncology is required. The ideal candidate will be a highly motivated individual who enjoys fast paced biotech environment. You thrive in a collaborative work environment and are skilled at advancing multiple projects concurrently. Knowledge of state-of-art immunotherapy and its applications. As part of the Legend Biotech R&D team and under minimal supervision, you will be responsible for timely execution and delivery of projects in our discovery pipeline.

Key Responsibilities

Lead, design and optimize research with aims of exploring next generation cell therapies using in-vivo CAR-T.
Contribute to project creation and formation through dissection of published literature to find novel solutions to in-vivo cell therapy problems.
Isolate immune cells from leukopak or blood of healthy donors or patients and execute the evaluation of in-vivo CAR virus using a battery of in-vitro assays and in-vivo mice models.
Perform treatment of solid tumor research requiring cell biology techniques including cell culture, transfection, FACS, and cell-based functional assays.
Package and titer engineered viruses to infect immune cells in vitro and in vivo; Characterize virus particles with protein and PCR based assays; Measure transduction rate using flow and VCN analysis.
Generate, manage, evaluate, and maintain critical data in a highly organized manner, including the use of ELN.
Deliver result to meet timeline with accountability through presentation to a wide range of audiences of internal group meetings and other forums.
Maintain compliance with GLP and EHS protocols.

Requirements

PhD in Immunology or related discipline.
4 years of experience in the field of cell and gene therapy, in vivo CAR-T experience preferred.
Extensive experience in immune cell-based analytics and assay development including but not limited to advanced multi-parameter flow-cytometry, immunogenicity assay such as cytotoxicity assay, cytokine release ELISA/MSD multiplex assays.
Experience with lentivirus particle characterization and quantification using molecular (VCN) and flow-based assays.
Experience with solid tumor models and in vivo cell-specific gene delivery is a plus.
Track record of productivity is evidenced by publications or patents.
Be able to work independently to plan and timely execute research projects
Deep knowledge of immunology and immunotherapy; a deep understanding of solid tumor models is preferred
Proficient in advanced gene delivery methods using LVV, VLP or LNP technologies
Strong experience with lentivirus production, tittering and transduction.
Working molecular biology and cellular biology knowledge in design and evaluation of modified viral vectors
Strong multitasking, problem-solving and collaborative skills
Excellent verbal and written communication skills

#Li-JR1

#Li-Onsite

Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.

Work Authorization & Employment Eligibility

Applicants must be authorized to work in the United States. As part of our commitment to maintaining a lawful workforce and ensuring compliance with federal employment regulations, we participate in the E-Verify program. If you are selected for employment, you will be required to complete the Form I-9 process, and your employment eligibility will be verified through E-Verify in accordance with applicable federal law. We are committed to providing a fair, transparent, and welcoming hiring experience for all candidates.

EEO Statement

It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.

Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.

For information related to our privacy notice, please review: Legend Biotech Privacy Notice.

Apply Now

Refine Your Search

sr. scientist, bioinformatics jobs in pennsylvania

Sr. Scientist

Senior Scientist, Biology-Discovery

Sr. Scientist; Bioinformatic and Translational Science

Research Data Scientist - Molecular and Precision Medicine / Medicine

Sr. Scientist, Toxicology

John Otto Haas Molecular Ecologist; Morris Arboretum & Gardens

Bioinformatics Engineer

Senior Scientist, Chemistry

Data Analyst (Department of Radiology)

Bioinformatician A/B

Bioinformatician A

Sr. Scientist I LCMS

Computational Biologist

Scientist/Sr. Scientist/Principal Scientist

Senior Scientist, Reagent Technical Development and Operations (On-site)

Manager of Genomics Core

Molecular Biology Scientist/Senior Associate Scientist

Bioinformatics Engineer – Software Development - PHP (Remote)

Senior Scientist, Computational Safety & Exploratory Pharmacology

Postdoctoral Scholar - Public Health Sciences

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