Top 26 Bioengineering Jobs in Philadelphia Pa

Scientist
Legend Biotech US —Philadelphia, PA
- $96,267 - $126,351 a year
- Full-time
- Presentation skills
- Doctor of Philosophy
- US work authorization
Research Associate
Integral Molecular —Philadelphia, PA
- Office
- Bachelor's degree
- 1 year
Sr. Scientist, Analytical R&D
Merck —West Point, PA
- $117,000 - $184,200 a year
- Full-time
- Bachelor of Science
- Mid-level
- Bachelor's degree
- Paid holidays
- Health insurance
1d
Research Specialist A
University of Pennsylvania —Philadelphia, PA
- $44,500 - $53,750 a year
- Full-time
- Background check
- Bachelor of Science
- Maintenance
- Health insurance
- Dental insurance
Project Engineer
Globus Medical —Audubon, PA
- Full-time
- Mid-level
- Budgeting
- Mechanical knowledge
Research Investigator, Senior
University of Pennsylvania —Philadelphia, PA
- $79,500 - $105,000 a year
- Full-time
- Background check
- Medicine
- 5 years
- Health insurance
- Dental insurance
Biomechanics Associate (Ph.D.)
Exponent Inc. —Philadelphia, PA
- Email
- Anatomy knowledge
- Office
- Presentation skills
- 401(k)
8d
Manufacturing Leadership Development Program - Associate Specialist, Engineering
Merck —West Point, PA
- $71,900 - $113,200 a year
- Full-time
- Up to 50% travel
- Military
- Bachelor of Science
- Paid holidays
- Health insurance
3d
Validation Engineering Roles
Design Group —Philadelphia, PA
- Full-time
- Background check
- Engineering
- Pass drug screening
Sr Project Engineer
Globus Medical —Audubon, PA
- Full-time
- Writing skills
- Clinic
- Analysis skills
Sr Manager Research Strategy & Acceleration
Children’s Hospital of Philadelphia —Philadelphia, PA
- $142,700 - $189,100 a year
- Full-time
- Microsoft Word
- Management
- Master's degree
Quick Apply
Senior Managing Scientist - Biomechanics (Ph.D.)
Exponent Inc. —Philadelphia, PA
- $180,000 - $210,000 a year
- Email
- 7 years
- Office
- Doctor of Philosophy
- 401(k)
Associate Director of Gene Editing
University of Pennsylvania —Philadelphia, PA
- $66,000 - $80,000 a year
- Full-time
- Background check
- 3 years
- University
- Health insurance
- Dental insurance
Senior Scientist, Viral Upstream Process Development
CEDENT —Philadelphia, PA
- Master's degree
- Math
- Bachelor's degree
SENIOR PROJECT ENGINEER
Globus Medical —Audubon, PA
- Full-time
- Writing skills
- Clinic
- Analysis skills
Upstream Principal Scientist, Vector Biology
Legend Biotech US —Philadelphia, PA
- $146,410 - $192,164 a year
- Full-time
- 5 years
- Doctor of Philosophy
- US work authorization
Quick Apply
Research Postdoctoral Fellow - Mossé and Weber Labs
Children’s Hospital of Philadelphia —Philadelphia, PA
- $20,800 - $110,400 a year
- Full-time
- Doctoral degree
- Analysis skills
- Team management
Quick Apply
System MAC Movement Scientist
Shriners Hospitals for Children —Philadelphia, PA
- $51.79 - $77.68 an hour
- Full-time
- 18 years or older
- Databases
- Analysis skills
Quick Apply
14d

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Scientist

Legend Biotech US -
Philadelphia, PA

Apply Now

Job Details

Full-time
$96,267 - $126,351 a year

Qualifications

Data integrity assurance
Research design
Laboratory experiment design
Advanced cell culture techniques
Experimental data reports
Record keeping
Laboratory project records management
Technical documentation
Design of experiments
Technical report writing
Data integrity and documentation
Laboratory reports
Data management
Technology transfer (scale-up process)
Bioreactors
Technical research projects
Scalability
Research data analysis
Cross-functional collaboration
Research findings presentation
Research & development
Cross-functional communication
Scientific reports
Assays

Full Job Description

Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases. From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting-edge therapies for patients worldwide.

Legend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI® (ciltacabtagene autoleucel; cilta-cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma.

Legend Biotech is seeking a Scientist as part of the Research and Development team based in Philadelphia, PA.

Role Overview

Legend Biotech seeks an experienced Scientist to join the Upstream team, Vector Biology in Philadelphia, with a focus on in-vivo CAR-T programs. This independent contributor role will own hands-on execution and data-driven
development of lentiviral vector upstream processes, including seed train strategy and scale-up from small-scale to 40-Liter bioreactor runs. This Scientist position will closely work with Molecular Biology, Downstream, Analytical and Technical development partners to ensure end-to-end process alignment, support comparability strategy and readiness, and enable efficient, high-quality technology transfer.

Key Responsibilities

Define and optimize the upstream process from shake flask through bioreactors, scaling to 40-L with reproducible performance and clear rational for operating parameters.
Execute and optimize lentiviral vector production workflows supporting in-vivo CAR-T application, including transient transfection optimization and/or stable cell line optimization.
Perform media optimization, feeding strategy development, and process control adjustments to improve yield, quality, scalability and robustness.
Develop and execute fit-for-purpose studies to support scalability and readiness.
Collaborate with internal teams within Vector Biology and coordinate cross-functional activities to support technology transfer to internal Technical Development team.
Contribute technical input to cross-functional discussions on experimental design, comparability strategy, and progression of exploratory work into formal process development.
Independently plan, perform, analyze, and interpret experiments with minimal supervision.
Deliver clear data summaries and evidence-based recommendations to Vector Biology and cross-functional teams.
Prepare high-quality technical reports, study summaries, and slide decks to support decisions on the upstream process development.
Adhere to BSL-2 biosafety standards and Legend policies, maintaining accurate and compliant electronic lab notebooks and documentation.
Ensure experimental reproducibility and data integrity through detailed and organized record-keeping.

Requirements

MS degree with 4+ years; or PhD degree with 1 year's prior industry experience in Bioengineering, Virology, Cell biology, Chemical Engineering, or related field.
Hands-on experience in viral vector production, and characterization.
Experience with mammalian suspension cell culture, transient transfection, and upstream bioprocess development.
Strong technical background in molecular biology techniques, including plasmid construction, PCR/qPCR/dPCR based assay, and cell line development.
Demonstrated ability to design, execute, analyze, and troubleshoot complex experiments in a fast-paced R&D environment.
Experience scaling upstream processes from shake flasks to bioreactor system (up to 50 L preferred).
Experience supporting gene therapy platform development, preferably involving lentiviral vector applications.
Basic understanding of upstream process development and their impact on product quality.
Strong organizational and time management skills, with the ability to manage multiple projects and priorities.
Excellent analytical and problem-solving skills with the ability to interpret data and recommend next steps.
Proficiency in maintaining accurate experimental records and documenting data using electronic laboratory notebooks (ELNs) to ensure data traceability.
Excellent verbal and written communication skills, with experience preparing technical reports and presenting scientific findings to cross-functional teams.
Ability to work both independently and collaboratively in a multidisciplinary research environment.
Adaptable, self-motivated, and eager to learn new technologies and experimental approaches.

#Li-JR1
#Li-Onsite

Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.

Work Authorization & Employment Eligibility

Applicants must be authorized to work in the United States. As part of our commitment to maintaining a lawful workforce and ensuring compliance with federal employment regulations, we participate in the E-Verify program. If you are selected for employment, you will be required to complete the Form I-9 process, and your employment eligibility will be verified through E-Verify in accordance with applicable federal law. We are committed to providing a fair, transparent, and welcoming hiring experience for all candidates.

EEO Statement

It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.

Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.

For information related to our privacy notice, please review: Legend Biotech Privacy Notice.

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Refine Your Search

bioengineering jobs in philadelphia pa

Scientist

Research Associate

Sr. Scientist, Analytical R&D

Research Specialist A

Project Engineer

Research Investigator, Senior

Biomechanics Associate (Ph.D.)

Manufacturing Leadership Development Program - Associate Specialist, Engineering

Validation Engineering Roles

Sr Project Engineer

Sr Manager Research Strategy & Acceleration

Senior Managing Scientist - Biomechanics (Ph.D.)

Associate Director of Gene Editing

Senior Scientist, Viral Upstream Process Development

SENIOR PROJECT ENGINEER

Upstream Principal Scientist, Vector Biology

Research Postdoctoral Fellow - Mossé and Weber Labs

System MAC Movement Scientist

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