Top 109 Senior program manager Jobs in Philadelphia Pa

Senior IIS and Grants Manager
INSPYR Solutions —King of Prussia, PA
- $72.98 an hour
- Contract
- Hybrid work
- 8 years
- Presentation skills
- Bachelor's degree
- Health insurance
- 401(k)
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Senior IIS and Grants Manager - Hybrid
Ledgent Technology —King of Prussia, PA
- $53.57 - $74.29 an hour
- Full-time
- 8 years
- Presentation skills
- Bachelor's degree
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Senior Manager, STEM Summer and Auxiliary Programs
Lavner Education —Plymouth Meeting, PA
- $80,000 - $100,000 a year
- Full-time
- Research
- Bachelor's degree
- Senior level
- Health insurance
- 401(k)
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Senior IIS and Grants Manager - Hybrid
Ledgent Technology —King of Prussia, PA
- $53.57 - $74.29 an hour
- Full-time
- 8 years
- Presentation skills
- Bachelor's degree
Quick Apply
6d
Senior Manager, Workforce Development
Urban League of Greater Philadelphia —Philadelphia, PA
- $85,000 - $95,000 a year
- Full-time
- Hybrid work
- Management
- 5 years
- Databases
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Sr. Program Lead, Professional Education, CKMH
American Heart Association —Philadelphia, PA
- $84,400 - $113,000 a year
- Full-time
- Remote
- 5 years
- Bachelor's degree
- Fair chance
- Wellness program
- Paid holidays
Senior Program Manager
Honeywell Aerospace —Lansdale, PA
- Full-time
- Senior level
Senior Program Manager Consultative Cardiology
Penn Medicine —Philadelphia, PA
- Monday to Friday
- Bachelor's degree
- Recruiting
- Outpatient
- Tuition reimbursement
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President - Trinity Health Mid-Atlantic South (Mercy Fitzgerald and Saint Francis Hospitals)
Trinity Health —Philadelphia, PA
- Full-time
- Psychiatry
- Hospital
- Travel
Senior Operations Logistics Manager
Naval Systems, Inc. —Philadelphia, PA
- $145,000 - $155,000 a year
- Full-time
- Research
- 3 years
- Bachelor's degree
- Paid holidays
- Disability insurance
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Senior Program Manager / Account Manager
CapTech Consulting —Philadelphia, PA
- Full-time
- Computer Science
- Bachelor's degree
- US work authorization
- Loan repayment program
- Disability insurance
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Sr. Manager - Clinical Change Adoption & Readiness
CVS Health —Blue Bell, PA
- $67,900 - $182,549 a year
- Full-time
- Hybrid work
- 7 years
- Analysis skills
- Bachelor's degree
- Health insurance
- Dental insurance
Senior Program Manager- St. Columba's
Project Home —Philadelphia, PA
- $71,035 a year
- Weekends as needed
- Master of Social Work
- ServSafe
- Residential
- Paid parental leave
- Disability insurance
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Senior Program Manager
Calcium+Company —Philadelphia, PA
- Full-time
- Microsoft Excel
- Bachelor's degree
- Mentoring
Sr. Project Manager
MustardSeed PMO —Philadelphia, PA
- $92,000 - $138,000 a year
- Full-time
- Remote
- Organizational skills
- Senior level
- Leadership
- Health savings account
- Paid holidays
Quick Apply
Senior Project Manager, Program Lead (Construction)
Core States Group —Philadelphia, PA
- $130,000 - $145,000 a year
- Full-time
- Remote
- Microsoft Office
- Bachelor's degree
- Travel
- Paid parental leave
- Health savings account
Senior Manager, Technology Category Management
Cencora —Conshohocken, PA
- $93,500 - $187,000 a year
- Full-time
- 7 years
- Master's degree
- Bachelor's degree
- Paid parental leave
- Health insurance
10d
Senior Director, Program Management & Strategic Initiatives
Clarivate —Philadelphia, PA
- Full-time
- Hybrid work
- Senior level
- Master of Business Administration
Business Integrity Trade Compliance Senior Manager
PRICE WATERHOUSE COOPERS —Philadelphia, PA
- $91,000 - $321,500 a year
- 6 years
- High school diploma or GED
- Fair chance
- Paid holidays
- Health insurance
12d
Senior Project and Program Manager - Sales Enablement Programs
Wolters Kluwer —Philadelphia, PA
- $78,400 - $136,950 a year
- Full-time
- 5 years
- Analysis skills
- Bachelor's degree
- Commuter assistance
- Paid parental leave

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Senior IIS and Grants Manager

INSPYR Solutions -
King of Prussia, PA

Quick Apply

Job Details

Contract
$72.98 an hour

Benefits

Health insurance
401(k)

Qualifications

Presentation software
Regulatory compliance
Bachelor's degree
Pharmaceutical company experience
Leading team collaboration initiatives
Presentation creation
Managing projects
Medical affairs
Cross-functional team management
Project stakeholder communication
Cross-functional communication
Excel data analysis

Full Job Description

Title: Senior IIS and Grants Manager
Location: King of Prussia, hybrid onsite
Duration: 6 months
Compensation: 72.98
Work Requirements: US Citizen, GC Holders or Authorized to Work in the US

Job Title: Senior IIS and Grants Manager

The IIS & Grants Manager is responsible for driving operational excellence across Investigator-Initiated Studies (IIS) and Medical Grants within Medical Affairs. This role partners closely with Disease Area (DA) teams, regional medical teams, and cross-functional stakeholders to ensure efficient, compliant, and high-quality execution of grants and IIS processes.
The position plays a critical role in governance, process standardization, budget oversight, and inspection readiness—ensuring that all IIS and grants activities align with medical strategy and organizational objectives in a global, matrixed environment.

Job Description:

Key Responsibilities:
1) IIS & Grants Operations (Primary Focus)

Lead end-to-end coordination of IIS and grants processes, including intake, review cycles, governance forums, and milestone tracking.
Ensure strong alignment of IIS and grants activities with medical strategy and organizational priorities.
Standardize and harmonize processes across legacy organizations, supporting integration and consistency.
Oversee governance cadence, including review committee planning, documentation, and decision tracking.
Ensure operational readiness through adherence to SOPs, complete documentation, and effective cross-functional handoffs.

2) Budget, Timeline & Performance Management

Partner with Finance to plan, track, and reconcile IIS and grants budgets.
Identify and communicate financial variances, risks, and opportunities while maintaining audit-ready documentation.
Develop and maintain integrated project plans and milestone trackers (e.g., Gantt schedules) for IIS and grants portfolio activities.
Monitor progress against timelines, proactively mitigate risks, and provide regular status updates and dashboards.

3) Process Excellence, Quality & Compliance

Ensure all IIS and grants processes meet internal SOPs, policies, and external regulatory requirements.
Maintain audit- and inspection-ready documentation across all activities, including decisions, approvals, and financial tracking.
Support SOP development, updates, and implementation aligned with evolving business needs.
Drive continuous improvement initiatives, including process optimization, template standardization, and lessons learned.

4) Tools, Reporting & Insights

Build and maintain dashboards, trackers, and portfolio reporting tools (e.g Insights Modul, Excel-based trackers).
Deliver clear, concise reporting on IIS and grants portfolio performance, including KPIs, risks, and mitigation strategies.
Generate executive-ready summaries and insights to support data-driven decision-making for senior Medical Affairs leadership.

5) Cross-Functional Collaboration & Communication

Act as a central liaison across Medical Affairs, Finance, Compliance, Legal, and external partners.
Translate operational updates into clear narratives for leadership, highlighting progress, risks, and decisions needed.
Support change management initiatives related to IIS and grants processes, tools, and governance models.

Required Qualifications:

Bachelor's degree required. Advanced degree and/or PMP or equivalent project management certification desirable.
8-10+ years of relevant experience in pharma/biotech within Medical Affairs operations, clinical/medical program management, or closely related functions in a global, matrixed setting.
Demonstrated experience managing IIS and/or medical grants processes, including governance and compliance requirements.
Proven ability to lead cross-functional initiatives without direct authority.
Proficiency and strong Excel/PowerPoint skills.
Excellent communication and stakeholder engagement skills, with experience presenting to senior leadership.

Preferred / Nice to Have Qualifications:

Process design/continuous improvement (templates, SOPs, training).
Familiarity with international compliance regulations and requirements.

4. What This Role Is Not

No people management responsibilities.

Why This Role Is Attractive

Opportunity to play a central role in shaping and standardizing IIS and grants operations during a period of organizational transformation.
High visibility position supporting global Medical Affairs strategy and execution.
Exposure to senior leadership and cross-functional decision-making.
Collaborative environment where contributions directly impact process innovation and operational excellence.

#IND-TELECOM

Our benefits package includes: (EXCLUDE on perm placements)

Comprehensive medical benefits
Competitive pay, 401(k)
Retirement plan
…and much more!

About INSPYR Solutions:
As a leading information technology partner, we connect top IT talent with our clients to provide innovative business solutions through our IT Staffing, Professional Services, and Infrastructure Solutions divisions. We understand and value the unique needs of highly-skilled information technology professionals in the industry and always strive to stay above the curve. Our company was founded on the following core values: Be the Best, Understand the Urgency, Never Ever Give Up, Have the Courage to Excel, and Make a Contribution. We take pride in our business model and strive to create a positive workplace environment through an exemplary culture.

INSPYR Solutions provides Equal Employment Opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability, or genetics. In addition to federal law requirements, INSPYR complies with applicable state and local laws governing nondiscrimination in employment in every location in which the company has facilities.

Information collected and processed through your application with INSPYR Solutions (including any job applications you choose to submit) is subject to INSPYR Solutions’ Privacy Policy and INSPYR Solutions’ AI and Automated Employment Decision Tool Policy: https://www.inspyrsolutions.com/policies/. By submitting an application, you are consenting to being contacted by INSPYR Solutions through phone, email, or text.

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Refine Your Search

senior program manager jobs in philadelphia pa

Senior IIS and Grants Manager

Senior IIS and Grants Manager - Hybrid

Senior Manager, STEM Summer and Auxiliary Programs

Senior IIS and Grants Manager - Hybrid

Senior Manager, Workforce Development

Sr. Program Lead, Professional Education, CKMH

Senior Program Manager

Senior Program Manager Consultative Cardiology

President - Trinity Health Mid-Atlantic South (Mercy Fitzgerald and Saint Francis Hospitals)

Senior Operations Logistics Manager

Senior Program Manager / Account Manager

Sr. Manager - Clinical Change Adoption & Readiness

Senior Program Manager- St. Columba's

Senior Program Manager

Sr. Project Manager

Senior Project Manager, Program Lead (Construction)

Senior Manager, Technology Category Management

Senior Director, Program Management & Strategic Initiatives

Business Integrity Trade Compliance Senior Manager

Senior Project and Program Manager - Sales Enablement Programs

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