Top 321 Senior applied scientist Jobs in Redmond, Wa

Immunology Senior Research Scientist - Single-Cell Genomics
Vertex Pharmaceuticals —Seattle, WA
- $124,200 - $186,400 a year
- Full-time
- Master's degree
- Analysis skills
- Bachelor's degree
- Loan repayment program
- Dental insurance
Immunology Senior Research Scientist - Flow Cytometry
Vertex Pharmaceuticals —Seattle, WA
- $124,200 - $186,400 a year
- Full-time
- Master's degree
- Analysis skills
- Bachelor's degree
- Loan repayment program
- Dental insurance
Immunology Senior Research Scientist - Spatial Transcriptomics
Vertex Pharmaceuticals —Seattle, WA
- $124,200 - $186,400 a year
- Full-time
- Master's degree
- Analysis skills
- Bachelor's degree
- Loan repayment program
- Dental insurance
Scientist I Biopreservation
Biolife Solutions, Inc. —Bothell, WA
- $109,593 - $158,910 a year
- Full-time
- Background check
- Bachelor of Science
- Pass drug screening
- Disability insurance
- Health insurance
Seattle Research Site Head (Immunology)
Vertex Pharmaceuticals —Seattle, WA
- $268,000 - $402,000 a year
- Full-time
- Medicine
- 7 years
- Doctor of Philosophy
- Loan repayment program
- Dental insurance
Senior Applied Scientist
Outreach —Seattle, WA
- $140,000 - $175,000 a year
- Full-time
- Computer Science
- Java
- Master's degree
- Health insurance
- Dental insurance
Senior Plasma Data Scientist
Helion —Everett, WA
- $210,000 - $250,000 a year
- Full-time
- Office
- 3 years
- Analysis skills
- Paid parental leave
- Paid holidays
Quick Apply
Senior Applied Scientist, Trust & Safety
DAT —Seattle, WA
- $183,000 - $226,000 a year
- Hybrid work
- Computer Science
- 5 years
- Doctor of Philosophy
- Health savings account
- AD&D insurance
Senior Applied Scientist
Microsoft —Redmond, WA
- $119,800 - $261,000 a year
- Full-time
- Background check
- Doctoral degree
- Computer Science
2d
Senior Data Scientist – Fusion Systems
Helion —Everett, WA
- $195,000 - $222,000 a year
- Full-time
- 7 years
- System design
- Office
- Paid parental leave
- Paid holidays
Quick Apply
Applied Researcher 2/ Senior Applied Researcher
Microsoft —Redmond, WA
- $102,100 - $261,000 a year
- Full-time
- Background check
- Doctoral degree
- Mid-level
Senior UX Researcher, Human Factors
Google —Seattle, WA
- $159,000 - $231,000 a year
- Full-time
- 3 years
- Bachelor's degree
- Doctor of Philosophy
- Paid holidays
- Disability insurance
11d
Senior Applied Scientist
Amazon.com Services LLC —Seattle, WA
- $167,100 - $226,100 a year
- Full-time
- 3 years
- Java
- Master's degree
- AD&D insurance
- Health insurance
Senior Applied Scientist, Applied AI Solutions GTM
Amazon Development Center U.S., Inc. —Seattle, WA
- $167,100 - $260,000 a year
- Full-time
- 5 years
- Master's degree
- Doctor of Philosophy
- AD&D insurance
- Health insurance
Senior Applied Scientist
Adobe —Seattle, WA
- $142,700 - $270,950 a year
- Full-time
- Computer Science
- Master's degree
- Doctor of Philosophy
Senior Applied Scientist, PXT
Amazon.com Services LLC —Seattle, WA
- $183,800 - $248,700 a year
- Full-time
- 6 years
- Java
- Master's degree
- AD&D insurance
- Health insurance
7d
Senior Applied Scientist, Last Mile Delivery
Amazon.com Services LLC —Bellevue, WA
- $167,100 - $260,000 a year
- Full-time
- 6 years
- Java
- Master's degree
- AD&D insurance
- Health insurance
7d
Senior Applied Scientist, Sponsored Products
Amazon.com Services LLC —Seattle, WA
- $183,800 - $260,000 a year
- Full-time
- 6 years
- Java
- Master's degree
- AD&D insurance
- Health insurance
Data Scientist III
Fred Hutchinson Cancer Center —Seattle, WA
- $126,984 - $200,678 a year
- Full-time
- Computer Science
- Java
- Master's degree
- Paid parental leave
- Paid holidays
Senior Environmental Scientist
HDR —Seattle, WA
- $106,820 - $183,120 a year
- Full-time
- Analysis skills
- Driver's License
- Bachelor's degree
- Paid holidays
- Disability insurance

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Immunology Senior Research Scientist - Single-Cell Genomics

Vertex Pharmaceuticals -
Seattle, WA

Apply Now

Job Details

Full-time
$124,200 - $186,400 a year

Benefits

Loan repayment program
Dental insurance
Tuition reimbursement
Paid time off
Vision insurance
401(k) matching

Qualifications

Optimizing workflow processes
Biology
Immunological assays
Molecular Biology
Biological sample management
Chemical Engineering
Standard Operating Procedures (SOPs) implementation
Workflow management (operations management method)
Technical documentation
Immunological laboratory techniques
Data quality assurance
Bioengineering
Leading laboratory workflow efficiency optimizations
Human genomics
DNA sequencing
Flow cytometers
Assay development
Master's degree
Implementing laboratory quality control protocols
Collaborative research
Quality performance measurement
Analysis skills
Policy & process development
Medical research
Bachelor's degree
Doctor of Philosophy
Scientific protocols
Laboratory standard operating procedures
Experimental design
Research data analysis

Full Job Description

Job Description

At Vertex, we are relentless in our pursuit of transformative solutions for patients with serious diseases. Our innovative approach to research and development has positioned us as a leader in the biotechnology industry. We are seeking a highly motivated and innovative Senior Scientist, Single-Cell Genomics to join a multidisciplinary research team focused on advancing the understanding of human disease biology and enabling translational research through state-of-the-art cellular and molecular profiling approaches.

The successful candidate will lead the design, execution, optimization, and interpretation of single-cell genomics and multi-omics workflows, with a primary emphasis on wet-lab experimental biology. This role will focus on implementation of 10x Genomics-based and related single-cell platforms to generate high-quality datasets from complex tissue and peripheral biological samples, including applications in immune cell profiling and disease-relevant contexts. The ideal candidate will bring deep hands-on expertise in executing single-cell assays and the ability to partner closely with computational scientists and cross-functional research teams.

The candidate will contribute to developing mechanistic understanding of disease biology and support translational research, biomarker development, and therapeutic hypothesis generation.

This is an exciting opportunity for a scientist who is passionate about building and applying cutting-edge single-cell technologies to support target discovery, translational biology, and mechanistic investigation in a collaborative biotech environment.

Key Duties & Responsibilities:

Execute Single-Cell Genomics and Multi-Omics Workflows

Process primary samples and cell-based systems for single-cell applications, including tissue dissociation, cell isolation, enrichment, counting, and viability assessment
Generate high-quality libraries for transcriptomic, epigenomic, and/or immune profiling applications
Perform sample and library QC using standard methods such as Qubit, TapeStation, and Bioanalyzer
Perform end-to-end single-cell genomics and multi-omics workflows, including emerging modalities such as multiome and CITE-seq where appropriate, from sample acquisition through library preparation and sequencing
Establish and refine SOPs, assay documentation, and experimental best practices

Workflow Optimization and Troubleshooting

Execute and troubleshoot assays using 10x Chromium and related technologies
Troubleshoot technical issues across the workflow, including sample quality, library complexity, and sequencing performance
Optimize workflows as needed to maximize sample quality, cell recovery, and reproducibility across studies
Benchmark new methods and contribute to adoption of next-generation single-cell and multi-omics capabilities

Coordination and Cross-Functional Collaboration

Coordinate with internal core groups or external vendors for sequencing, run tracking, and data generation
Support or interface with flow cytometry and cell sorting activities where needed to enable downstream genomics workflows
Collaborate closely with bioinformatics and computational biology teams to support interpretation of complex datasets and enable biologically meaningful insights
Perform critical evaluation of assay and sequencing metrics, including read depth, mapping performance, cell recovery, and QC thresholds

Knowledge and Skills:

Deep hands-on expertise in single-cell genomics workflows, with particular experience in 10x Genomics platforms
Strong wet-lab background in NGS library preparation, molecular biology, and complex sample processing
Demonstrated ability to independently design, execute, troubleshoot, and optimize technically sophisticated experiments
Experience with downstream computational analysis of single-cell datasets is not required but would be considered a significant advantage
Strong attention to detail and commitment to high standards in experimental rigor, data quality, and documentation
Effective communicator and collaborative scientist who works well in multidisciplinary, matrixed research environments

Education and Experience:

PhD in Genomics, Molecular Biology, Chemical Engineering, Bioengineering, or a related discipline with 2+ years of relevant experience; or
Master’s degree with 6+ years of relevant experience; or
Bachelor’s degree with 8+ years of relevant experience

Pay Range:

$124,200 - $186,400

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]

Apply Now

Refine Your Search

senior applied scientist jobs in redmond, wa

Immunology Senior Research Scientist - Single-Cell Genomics

Immunology Senior Research Scientist - Flow Cytometry

Immunology Senior Research Scientist - Spatial Transcriptomics

Scientist I Biopreservation

Seattle Research Site Head (Immunology)

Senior Applied Scientist

Senior Plasma Data Scientist

Senior Applied Scientist, Trust & Safety

Senior Applied Scientist

Senior Data Scientist – Fusion Systems

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Senior Applied Scientist

Senior Applied Scientist, Applied AI Solutions GTM

Senior Applied Scientist

Senior Applied Scientist, PXT

Senior Applied Scientist, Last Mile Delivery

Senior Applied Scientist, Sponsored Products

Data Scientist III

Senior Environmental Scientist

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