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Sr. Director of Sponsor Operations

CRIO Inc
Remote

Quick Apply

Job Details

Full-time
$160,000 - $185,000 a year

Benefits

Health insurance
Unlimited paid time off
Dental insurance
Work from home
Vision insurance
401(k) matching
Life insurance

Qualifications

Data integrity assurance
Data validation techniques
Regulatory compliance
Clinical research compliance
Health information data integrity
Data quality monitoring
Customer engagement
CDISC standards
Managing clinical research teams
Leading team collaboration initiatives
Schema mapping design
Managing projects
Legal compliance
Cross-functional team management
Project stakeholder communication
Cross-functional communication
Senior leadership

Full Job Description

CRIO is a leading provider of eSource solutions for clinical research. Our platform streamlines clinical data collection and management, ensuring protocol compliance and reducing errors. By eliminating paper binders and automating workflows, we help clinical trial sites and sponsors save time and money, improve data quality, and enhance patient safety. Our digital-first, site-centric approach supports virtual, hybrid, and traditional study structures, making clinical trials more efficient and effective.

Founded in 2015 by a clinical trial site owner seeking to improve his own business, today CRIO is the industry leader in site eSource with a fast-growing presence serving sponsors and CROs. CRIO is in use on 6000+ protocols at more than 2500 sites in 30 countries. In fact, the strength of our site community drives our growth which is why we place so much value on hands-on clinical research experience.

Position Summary

The Senior Director of Sponsor Operations is responsible for building, scaling, and leading CRIO’s enterprise sponsor business, including Central eSource programs across global pharmaceutical and CRO organizations.

This role owns the end to end sponsor lifecycle from initial engagement through multi study execution and long term expansion. The Head of Sponsor Operations ensures consistent, high quality delivery across all enterprise sponsor programs while establishing scalable operational frameworks that enable CRIO to grow its sponsor footprint effectively.

A critical component of this role is ownership of clinical data strategy and execution across sponsor programs, including data standards, integration alignment, data quality, and regulatory compliance. This individual ensures that CRIO’s eSource data is structured, mapped, validated, and delivered in a way that meets sponsor expectations and industry requirements.

Operating at the intersection of sponsor strategy, clinical operations, and technical data delivery, this role partners closely with Product, Engineering, and Customer Experience to align enterprise sponsor needs with CRIO’s platform capabilities and long term roadmap.

Key Responsibilities

Enterprise Sponsor Strategy and Growth

Own the operational strategy for all enterprise sponsor programs including Lilly, ICON, Moderna, and future enterprise accounts
Partner with Sales and Executive Leadership to support enterprise deal strategy, solution design, and expansion planning
Define scalable Central eSource operating models across sponsor organizations
Identify opportunities to expand sponsor adoption across additional studies, geographies, and use cases

Sponsor Portfolio Ownership and Execution

Own delivery across all active and planned studies within enterprise sponsor portfolios
Ensure consistency in execution, timelines, and quality across all sponsor engagements
Establish standardized workflows, templates, and delivery frameworks across sponsors
Drive visibility through executive level reporting on portfolio health, risks, and performance
Establish governance models for enterprise sponsor accounts including regular executive reviews and QBR structures
Serve as senior leadership point of contact for sponsor organizations
Lead high level sponsor discussions related to scope, timelines, data expectations, and escalations

Clinical Data Strategy and Oversight

Own the clinical data framework for all sponsor programs, ensuring alignment with industry standards and sponsor expectations
Oversee CDASH mapping, data structuring, and standardization across all studies
Ensure consistency and quality of data capture, validation, and downstream usability
Define and enforce data governance practices across sponsor portfolios
Oversee the alignment of eSource data with EDC systems, ensuring accurate, complete, and compliant data transfer
Ensure integration outputs meet sponsor requirements for data quality, structure, and format
Establish processes for - Data review and validation, Query management alignment with sponsor workflows, XML and structured data output review

Operational Architecture and Central eSource Design Alignment

Oversee enterprise Central eSource design frameworks, ensuring alignment with sponsor protocols, regulatory requirements, and site workflows
Define data capture logic, workflow structures, and role based access models across studies
Drive standardization across study configuration, amendment processes, and UAT strategies
Establish repeatable deployment models that balance flexibility with scalability
Identify and champion opportunities to embed AI-driven automation across sponsor workflows, including Central eSource design configuration, data validation, query management, and amendment processing
Partner with Product and Engineering to define enterprise requirements for AI-assisted capabilities, such as intelligent data capture, protocol deviation detection, and EDC integration quality checks
Stay ahead of emerging AI applications in clinical data and eSource, translating sponsor needs and operational patterns into actionable input for CRIO's AI product roadmap

Integration and Technical Delivery Alignment

Partner with Product and Engineering to define and prioritize enterprise integration requirements across EDC, CTMS, eRegulatory, and external systems
Ensure data integrity and consistency across all integration points
Serve as executive escalation point for complex technical, data, and integration challenges

Cross Functional Leadership and Alignment

Lead coordination across Sponsor Operations, Central eSource design, Data Migration, Product, Engineering, and Customer Experience teams
Ensure alignment between sponsor requirements and internal delivery capabilities
Identify and resolve systemic gaps across workflows, data handling, and handoffs
Partner with Product Leadership to influence roadmap priorities based on enterprise data and integration needs
Drive accountability across all functions involved in sponsor delivery

Qualifications

Required

10+ years of experience in clinical research technology, data management, sponsor operations, or clinical trial systems
5-7+ years of operational team and/or personnel management
Strong background in clinical data management, including:
CDISC standards (CDASH, USDM, SDTM, etc.)
Data mapping and transformation
Data validation and quality processes
Proven experience managing enterprise sponsor or CRO relationships across multiple studies or programs
Deep understanding of clinical trial workflows, site operations, and regulatory requirements
Experience working with eSource, EDC, CTMS, or related clinical platforms
Demonstrated ability to lead complex, data intensive, cross functional programs
Exceptional communication and executive presence

Preferred

Exposure with Central eSource concept models or similar sponsor site integrated workflows
Familiarity with HL7 FHIR, API based integrations, or structured data exchange models
Experience overseeing data migration or large scale data transformation initiatives
Background in CRO, sponsor organization, or clinical technology vendor environment
Prior experience scaling teams in a high growth environment

Benefits & Perks:

Work from anywhere
Unlimited PTO
401k company match
Healthcare
Dental
Vision (Company Paid 100%)
Life insurance
Professional development
Work From Home Expense Reimbursement

Working Conditions

This is a full-time, remote or hybrid position. Occasional travel may be required based on client timelines and sponsor engagement needs. Flexibility may be required to align with sponsor and project schedules across time zones.

Equal Employment Opportunity:

CRIO is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All employment decisions are made based on qualifications, merit, and business need without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran status, disability status, age, or any other basis protected by federal, state, or local law.

Disability Accommodation Statement:

We are committed to providing reasonable accommodations to individuals with disabilities in the application and interview process. If you require accommodation to participate in the application process, please contact Human Resources to request assistance.

Salary Range: $160,000 - $185,000

Quick Apply

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Position Summary

Key Responsibilities

Enterprise Sponsor Strategy and Growth

Sponsor Portfolio Ownership and Execution

Clinical Data Strategy and Oversight

Operational Architecture and Central eSource Design Alignment

Integration and Technical Delivery Alignment

Cross Functional Leadership and Alignment

Qualifications

Required

Preferred

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