Top 35 Senior manufacturing manager Jobs in Research Triangle Park Nc

Senior Manager: Manufacturing – Material Handling
Amgen —Holly Springs, NC
- $136,227.80 - $184,308.20 a year
- Doctoral degree
- Master's degree
- High school diploma or GED
Senior Manager, Operations Lead (Assembly and Packaging)
Genentech —Holly Springs, NC
- $116,900 - $217,100 a year
- Online Application
- Office
- 8 years
- Travel
Mfg Tecnologies Sr Mgr
Amgen —Holly Springs, NC
- $137,416.10 - $185,915.90 a year
- Doctoral degree
- English
- Master's degree
- Disability insurance
- Health insurance
Senior Manager: Manufacturing - Downstream Bulk Drug Substance
Amgen —Holly Springs, NC
- $136,227.80 - $184,308.20 a year
- Doctoral degree
- Master's degree
- High school diploma or GED
Manufacturing Programs Senior Manager: New Product Introduction (NPI)
Amgen —Holly Springs, NC
- $154,173 - $208,587 a year
- Doctoral degree
- High school diploma or GED
- Mentoring
- Disability insurance
- Health insurance
11d
Sr. Manager, Manufacturing Sciences & Technology
Asahi Kasei —Cary, NC
- $160,000 - $175,000 a year
- Full-time
- Hybrid work
- Engineering
- English
- Bachelor's degree
- Health insurance
Senior Manager – Manufacturing Programs - Process Owner Organization
Amgen —Holly Springs, NC
- $154,173 - $208,587 a year
- Doctoral degree
- Master's degree
- High school diploma or GED
Senior Regional Quality & Continuous Improvement Manager
Cornerstone Building Brands —Cary, NC
- Online Application
- 18 years or older
- 5 years
- Analysis skills
- Paid holidays
- Disability insurance
Quick Apply
2d
Senior Regional Quality Assurance Manager
Cornerstone Building Brands —Cary, NC
- Online Application
- Remote
- 18 years or older
- Engineering
- 8 years
- Paid holidays
- Disability insurance
Quick Apply
2d
Sr. Supervisor, Manufacturing - Small Scale Purification (Days)
Biogen —Research Triangle Park, NC
- $98,000 - $127,000 a year
- 12 hour shift
- 7 years
- High school diploma or GED
- Supervising experience
- Paid parental leave
- Employee stock purchase plan
Sr. Manager, Manufacturing Execution Systems (MES)
Novartis —Durham, NC
- $108,500 - $201,500 a year
- Full-time
- 8 years
- In-person
- Senior level
- Health insurance
- 401(k) matching
Sr. Manager, Supply Chain- Manufacturing
Kyowa Kirin North America —Cary, NC
- $154,400 - $180,200 a year
- Construction site
- Analysis skills
- Bachelor's degree
- Health savings account
- Disability insurance
Quick Apply
Senior Manager, QC Chemistry and Device Testing (CVRM)
Genentech —Holly Springs, NC
- $120,100 - $223,100 a year
- Online Application
- Bachelor of Science
- 3 years
- Bachelor's degree
- Relocation assistance
7d
Senior Associate Manufacturing - Continuous Improvement Lead
Amgen —Holly Springs, NC
- $86,048.05 - $116,417.95 a year
- Master's degree
- High school diploma or GED
- Experience equivalent to degree accepted
Senior Manager Strategic Marketing Advanced Manufacturing & Life Sciences
ARCO a Family of Construction Companies —Raleigh, NC
- Full-time
- Marketing
- 8 years
- Bachelor's degree
- Paid parental leave
- Paid holidays
Senior Manager, Microbiology (CVRM)
Genentech —Holly Springs, NC
- $120,100 - $223,100 a year
- Online Application
- Bachelor of Science
- Data analysis skills
- 3 years
- Relocation assistance
7d
Senior GMDP Quality Assurance Manager
WEP Clinical —Morrisville, NC
- Full-time
- Hybrid work
- Microsoft Word
- Microsoft Excel
- Microsoft Outlook
- Paid parental leave
- Health savings account
5d
Sr. Associate III, Compliance - QRM Lead
Biogen —Research Triangle Park, NC
- $111,000 - $149,000 a year
- Full-time
- 6 years
- Bachelor's degree
- Training & development
- Paid parental leave
- Employee stock purchase plan
Senior Manager, Compliance Manufacturing
FUJIFILM —Research Triangle Park, NC
- Bachelor's degree
- Continuous improvement
- Ability to sit for extended periods
Supply Chain and Engineering– Greenfield Manufacturing Senior Manager
Accenture —Raleigh, NC
- $122,700 - $338,300 a year
- Full-time
- Hybrid work
- Mentoring
- US work authorization
- Military encouraged
- Paid holidays
- Disability insurance

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Senior Manager: Manufacturing – Material Handling

Amgen -
Holly Springs, NC

Apply Now

Job Details

$136,227.80 - $184,308.20 a year

Qualifications

Manufacturing facility experience
Factory experience
Senior leadership

Full Job Description

US - North Carolina - Holly Springs

JOB ID: R-250514 LOCATION: US - North Carolina - Holly Springs WORK LOCATION TYPE: On Site DATE POSTED: Aug. 13, 2026 CATEGORY: Manufacturing SALARY RANGE: 136,227.80USD -184,308.20 USD

HOW MIGHT YOU DEFY IMAGINATION?

You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience, and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Be part of Amgen's newest and most advanced drug substance manufacturing plant. The Amgen FleX Batch facility combines the latest in disposable technologies with traditional stainless-steel equipment to allow for maximum flexibility in operations. The FleX Batch facility not only features the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it also integrates sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.

Senior Manager: Manufacturing – Material Handling

Live

What you will do

Let's do this. Let's change the world. As a Senior Manager of Manufacturing – Material Handling, you will provide leadership and guidance to the team responsible for 24/7 GMP material handling operations supporting manufacturing across the facility.

In this vital role as a member of the Manufacturing leadership team, the Senior Manager, Manufacturing – Material Handling, will collaborate cross-functionally to enable the manufacture of drug substance in a new state-of-the-art manufacturing facility. This role is responsible for leading and developing Material Handling Front-Line Managers who oversee teams supporting the receipt, staging, movement, storage, inventory control, and delivery of GMP materials between the warehouse and manufacturing operations. Additionally, you will be accountable for organizational design, hiring, development, and training compliance of the Material Handling organization to ensure safe, reliable, and uninterrupted manufacturing operations. The position will also provide leadership and oversight for operational readiness activities to ensure successful facility start-up and sustained commercial manufacturing performance.

Responsibilities:

Develop and retain a diverse, high-performing Material Handling organization in alignment with operational readiness schedules to support successful facility startup and commercial GMP operations.

Foster a strong safety, quality, and compliance culture while championing continuous improvement across all Material Handling activities.

Collaborate as one team with Manufacturing, Warehouse Operations, Quality, Engineering, Supply Chain, Process Development, Automation, and network partners to ensure reliable execution of manufacturing operations.

Lead the execution and continuous improvement of end-to-end material flow processes, ensuring the right materials are available at the right location and time to support uninterrupted manufacturing.

Oversee inventory accuracy, material reconciliation, cycle counting, and GMP inventory control processes while ensuring compliance with regulatory and internal quality requirements.

Own the Manufacturing Material Transfer Equipment program, ensuring equipment lifecycle management, availability, qualification, maintenance coordination, and operational readiness.

Partner with Supply Chain and Warehouse Operations to optimize material staging, replenishment strategies, and production scheduling while minimizing operational risk.

Provide leadership in troubleshooting operational issues affecting material availability and establish robust escalation and 24/7 support processes.

Lead investigations related to material handling deviations, inventory discrepancies, and material management events while driving effective root cause analysis and corrective actions.

Develop and implement departmental strategies aligned with organizational objectives while driving Operational Excellence, Lean Manufacturing, and continuous improvement initiatives.

Lead and support internal and regulatory inspections for areas of responsibility, including inspection readiness, response development, and sustainable compliance strategies.

Deliver against organizational financial commitments while optimizing labor, inventory utilization, and operational efficiency.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The experienced professional we seek is a collaborative partner with these qualifications.

Basic Qualifications:

Doctorate degree and 2 years of Manufacturing & Operations experience Or

Master’s degree and 6 years of Manufacturing & Operations experience Or

Bachelor’s degree and 8 years of Manufacturing & Operations experience Or

Associate's degree and 10 years of Manufacturing & Operations experience Or

High School diploma/GED and 12 years of Manufacturing & Operations experience

AND 2 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources

Preferred Qualifications

Demonstrated managerial experience supporting GMP manufacturing operations in a biologics or pharmaceutical manufacturing environment.

Experience leading GMP material handling, manufacturing logistics, inventory management, or warehouse operations supporting manufacturing.

Demonstrated experience implementing Operational Excellence, Lean Manufacturing, and continuous improvement methodologies.

Experience with electronic inventory management systems (SAP, MES, electronic batch records, barcode/RFID technologies, or equivalent).

Working knowledge of GMP material management, inventory control, material traceability, and regulatory compliance requirements.

Cross-functional experience partnering with Manufacturing, Supply Chain, Engineering, Quality, and Process Development organizations.

Excellent communication, leadership, organizational, and problem-solving skills with the ability to influence across multiple organizations.

Demonstrated ability to develop high-performing teams and foster an inclusive, accountable, and collaborative culture.

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

Vast opportunities to learn and move up and across our global organization

Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits

for a career that defies imagination

In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us.

careers.amgen.com

#AmgenNorthCarolina

Apply Now

Refine Your Search

senior manufacturing manager jobs in research triangle park nc

Senior Manager: Manufacturing – Material Handling

Senior Manager, Operations Lead (Assembly and Packaging)

Mfg Tecnologies Sr Mgr

Senior Manager: Manufacturing - Downstream Bulk Drug Substance

Manufacturing Programs Senior Manager: New Product Introduction (NPI)

Sr. Manager, Manufacturing Sciences & Technology

Senior Manager – Manufacturing Programs - Process Owner Organization

Senior Regional Quality & Continuous Improvement Manager

Senior Regional Quality Assurance Manager

Sr. Supervisor, Manufacturing - Small Scale Purification (Days)

Sr. Manager, Manufacturing Execution Systems (MES)

Sr. Manager, Supply Chain- Manufacturing

Senior Manager, QC Chemistry and Device Testing (CVRM)

Senior Associate Manufacturing - Continuous Improvement Lead

Senior Manager Strategic Marketing Advanced Manufacturing & Life Sciences

Senior Manager, Microbiology (CVRM)

Senior GMDP Quality Assurance Manager

Sr. Associate III, Compliance - QRM Lead

Senior Manager, Compliance Manufacturing

Supply Chain and Engineering– Greenfield Manufacturing Senior Manager

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