McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.
What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.
Sr. Director, Cyber Threat Detection & Response
Location: Richmond, VA, USA - 9954 Mayland Drive (on-site)
The Opportunity
The Sr. Director, Threat Detection and Response (TDR) is responsible for leading a comprehensive enterprise capability that designs, implements, and operates scalable detection and response mechanisms while driving remediation of security gaps across technology environments (cloud, endpoints, identity, network, applications, and data platforms). This leader partners closely with the CISO organization, Technology Leadership, risk/compliance, and business stakeholders to prioritize investments, set standards, and ensure measurable improvements in detection fidelity, response readiness, and remediation throughput.
This role requires strong technical depth in threat detection and response as well as the leadership maturity to operate at the executive level. The Director establishes TDR strategy, roadmaps, and success metrics; governs an operating rhythm for detection coverage and remediation execution; and ensures outcomes are delivered across multiple teams (often via influence).
Key Responsibilities
Define and own the enterprise TDR strategy and operating model (detection engineering, alerting standards, response readiness, and remediation governance) aligned to business risk and technology priorities.
Establish and report executive-level metrics and scorecards (e.g., detection coverage, alert quality, MTTD/MTTR, response readiness, remediation SLAs, risk reduction) and drive continuous improvement based on outcomes.
Lead selection, adoption, and lifecycle management of detection and response tooling and telemetry (SIEM, EDR/XDR, SOAR, UEBA, threat intel integrations, cloud logging, and case management), including integration standards and data quality requirements.
Partner with Security Operations (SOC/CSIRT), threat intelligence, vulnerability management, and platform teams to ensure detections map to prioritized threats and that response playbooks and automation are effective and current.
Establish remediation governance to drive closure of systemic security gaps identified through incidents, threat hunting, purple teaming, and control validation; ensure clear ownership, prioritization, timelines, and exception processes.
Drive enterprise telemetry and logging strategy in partnership with engineering and infrastructure: ensure critical systems are instrumented, logs are retained appropriately, and detections can be built and tuned against reliable data sources.
Lead and develop TDR talent (leaders, detection engineers, analysts) through hiring, coaching, performance management, and capability development; ensure teams have the training, tools, and operating discipline required for success.
Manage cross-functional stakeholder relationships and communications (Technology leaders, risk/compliance, audit, legal/privacy as needed), translating technical risk into business impact and driving alignment on funding, priorities, and delivery commitments.
Provide governance for incident and post-incident remediation: ensure lessons learned translate into durable control improvements, and conduct regular exercises/tabletops to validate readiness and benchmark progress.
Minimum Requirements
Degree or equivalent experience. Typically requires 15+ years of professional experience and 10+ years of diversified leadership, planning, communication, organization, and people motivation skills (or equivalent experience).
Skills and Qualifications:
15+ years of cybersecurity experience with significant depth in threat detection, incident response, and security operations, including 10+ years leading teams and/or enterprise programs.
Hands-on and leadership experience with detection and response platforms and practices (SIEM content engineering, EDR/XDR, SOAR automation, threat intel integration, logging/telemetry pipelines, and case management).
Proven ability to drive remediation outcomes at scale establishing SLAs, clarifying ownership, prioritizing backlogs, and closing systemic gaps surfaced by incidents, hunts, and assessments.
Executive-ready communication and stakeholder management skills, including the ability to present risk, progress, and investment needs to senior leadership and influence decisions
Demonstrated ability to set strategy, secure organizational alignment/approvals, and deliver outcomes through multiple stakeholders (Security, Infrastructure, Cloud, Application/Product, and business teams).
Deep understanding of detection engineering, telemetry pipelines, and security analytics: SIEM content engineering, EDR/XDR detections, SOAR automation, threat intelligence integration, alert triage models, and case management workflows.
Strong risk communication skills: able to translate detection gaps and remediation tradeoffs into business impact, present to executives, and drive decisions to closure.
Experience establishing oversight metrics and operational rhythms (OKRs/KPIs, reporting, service reviews) and using data to improve alert quality, reduce noise, and accelerate remediation throughput.
Working knowledge of relevant governance and regulatory expectations and the ability to partner effectively with audit/compliance and privacy stakeholders while operating an effective detection and response capability.
Track record of building high-performing teams and leading with integrity, accountability, and operational discipline; known for clear communication, sound judgment, and reliable execution.
Experience developing multi-year roadmaps and influencing investment decisions (people, tooling, telemetry, automation) to improve enterprise detection and remediation outcomes.
Proven capability managing vendor relationships and service contracts for security tooling and managed services, including defining requirements and measuring performance against outcomes.
Strong understanding of privacy considerations and appropriate monitoring practices; able to partner with Legal/Privacy and HR as needed and ensure monitoring and investigations remain within policy and regulatory boundaries.
Experience operating in hybrid/cloud environments and partnering with platform teams to instrument systems (cloud logging, identity signals, endpoint telemetry, network data) for reliable detections.
Strong strategic and tactical decision-makingable to balance speed and risk, define compensating controls, and drive complex remediation decisions across multiple owners.
Experience leading or sponsoring purple team activities, tabletop exercises, and control validation to continuously improve detection coverage and response playbooks.
Trusted leader who builds credibility with executives and teams through transparency, follow-through, and a strong culture of operational excellence.
Education Requirements
Bachelors degree in computer science, information security/assurance, engineering, or a related field; advanced degree preferred or equivalent experience.
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Certification Requirements
Relevant certifications (preferred): CISSP, CISM, GIAC/SANS, +, SSCP, or equivalent foundational security certification. TDR/SecOps certifications (a plus): Google Cloud Professional Cloud Security Engineer and/or Associate Cloud Engineer, Google Professional Cloud DevOps Engineer, and/or GIAC certifications (e.g., GSEC, GCIH) depending on role focus. and/or cloud/security engineering certifications aligned to the teams platforms.
About Medical-Surgical
McKesson Medical-Surgical (MMS) is a subsidiary and publicly reported segment of the McKesson Corporation. MMS distributes medical-surgical supplies, pharmaceuticals, diagnostic equipment and supplies, along with other solutions and services to virtually every type of healthcare setting and provider outside of the traditional hospital. These markets – often referred to as Alternate Care or Non-Acute Care – include physician offices, surgery centers, long-term care providers, laboratories, home health and hospice agencies, health systems, government facilities and online marketplaces and retailers.
Alternate Care markets are growing rapidly and MMS is proud to be a leader in this space. With a team of approximately 8,000 employees, a network of 15 distribution centers and approximately 900 delivery vehicles, we partner with more than 2,200 leading manufacturers and serve over 200,000 customer accounts across the U.S. Our catalog includes more than 280,000 SKUs of branded and private-label medical-surgical products – from bandages to specialty pharmaceuticals and COVID-19 tests.
Looking Ahead : A New Chapter for MMS
McKesson has announced its intent to separate MMS into an independent company – an exciting evolution that builds on MMS’s strong foundation and proven leadership in the Alternate Care space. As a standalone company, MMS would be positioned to unlock new opportunities to innovate, grow and lead with even greater agility and focus. We will also continue to be one of the largest medical-surgical distributors in the U.S., with over $11B in annual sales. This separation would accelerate our mission and empower us to shape a future defined by customer-centricity, bold thinking and operational excellence. For job seekers, it’s a unique moment to join a team that’s already making a meaningful impact and leading the way in shaping the future of healthcare delivery in Alternate Care settings – with even greater opportunity ahead as we prepare to become an independent company.
Career Level - M5
We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson,
Our Base Pay Range for this position
$172,000 - $286,600
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McKesson is an Equal Opportunity Employer
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