Top 136 Senior scientist Jobs in Ridley Park, Pa

Molecular Biology Scientist/Senior Associate Scientist
Legend Biotech US —Philadelphia, PA
- $93,463 - $122,670 a year
- Full-time
- Analysis skills
- Doctor of Philosophy
- Quality control
Quick Apply
Senior Clinical Scientist
CSL Behring —King of Prussia, PA
- Full-time
- Hybrid work
- Office
- 3 years
- Master's degree
3d
Senior Director, Oncology Pharmacology
Jazz Pharmaceuticals —Philadelphia, PA
- $232,000 - $348,000 a year
- Analysis skills
- Doctor of Philosophy
- Mentoring
- Health insurance
- Dental insurance
Senior Officer, Philadelphia Research and Policy Initiative
Pew Charitable Trusts —Philadelphia, PA
- $142,800 - $159,600 a year
- Full-time
- Hybrid work
- Bachelor of Science
- Office
- Analysis skills
- Disability insurance
- Health insurance
Senior Validation Scientist
Hikma Pharmaceuticals —Cherry Hill, NJ
- $56,950 - $95,000 a year
- Full-time
- Microsoft Word
- Microsoft Excel
- Ability to walk for extended periods
- Paid parental leave
- Paid holidays
Quick Apply
FSP Senior Scientist, Biomarkers
Thermo Fisher Scientific —Collegeville, PA
- Full-time
- Background check
- Pass drug screening
- Office
5d
FSP Senior Research Scientist-Dissolution Method Development
Thermo Fisher Scientific —Collegeville, PA
- Full-time
- Microsoft Word
- Ability to lift 50 pounds
- Supervising experience
11d
Senior Scientist
Frontage Laboratories —Exton, PA
- Full-time
- 3 years
- Master's degree
- Analysis skills
- Disability insurance
- Health insurance
Quick Apply
Senior Scientist, Biology-Discovery
Merck —West Point, PA
- $117,000 - $184,200 a year
- Full-time
- Master's degree
- Bachelor's degree
- Doctor of Philosophy
- Paid holidays
- Health insurance
5d
Scientist/Senior Scientist - Cell Bioassay/Potency
Frontage Laboratories —Exton, PA
- Full-time
- Management
- Bachelor of Science
- Bachelor's degree
- Disability insurance
- Health insurance
Quick Apply
Senior Scientist- Biologics
Frontage Laboratories —Exton, PA
- Full-time
- Master's degree
- Bachelor's degree
- Doctor of Philosophy
- Disability insurance
- Health insurance
Quick Apply
Senior Health Research Analyst
PHC Group —Philadelphia, PA
- Background check
- Doctor of Philosophy
- Criminal background check
- Flexible schedule
Scientist Senior
Frontage Laboratories —Exton, PA
- Full-time
- 3 years
- Doctor of Philosophy
- Senior level
- Disability insurance
- Health insurance
Quick Apply
Senior Scientist, Bioanalytics
International Flavors & Fragrances —Wilmington, DE
- Full-time
- 11+ years
- Master's degree
- Bachelor's degree
Research Scientist/Senior Research Scientist (Flow Chemistry)
Universal Display Corporation —Wilmington, DE
- $100,000 - $120,000 a year
- Full-time
- Doctor of Philosophy
- Organizational skills
- Senior level
- Health savings account
- Employee stock purchase plan
Senior Research Coordinator
Temple University —Philadelphia, PA
- Full-time
- Hybrid work
- Mid-level
- Databases
- Analysis skills
- Paid holidays
- Health insurance
10d
Senior Scientist Analytical Services
Charles River Laboratories —Wayne, PA
- $123,000 - $130,000 a year
- Full-time
- 7 years
- Bachelor of Science
- Analysis skills
- Health insurance
- Paid time off
2d
Senior Epidemiologist, Research and Evaluation
HEALTH FEDERATION OF PHILADELPHIA —Philadelphia, PA
- $80,000 - $100,000 a year
- Full-time
- Office
- Master's degree
- Analysis skills
- AD&D insurance
- Disability insurance
Quick Apply
Senior Scientist, Product Development
Entegris —Ambler, PA
- $95,000 - $120,000 a year
- Full-time
- 3 years
- Presentation skills
- Doctor of Philosophy
- Paid holidays
- Health insurance
9d
Senior Director Clinical Research Scientist
Incyte Corporation —Wilmington, DE
- Medicine
- 5 years
- Bachelor of Science

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Molecular Biology Scientist/Senior Associate Scientist

Legend Biotech US -
Philadelphia, PA

Quick Apply

Job Details

Full-time
$93,463 - $122,670 a year

Qualifications

Biological safety protocols
Advanced cell culture techniques
Immunological assays
Biology research
Immunological laboratory techniques
Flow cytometers
Molecular cloning
Titration
Updating inventory records
Laboratory inventory records management
Gene expression analysis
Standard operating procedures (SOPs)
Production records
Cytometry
Laboratory compliance and regulatory documentation
Molecular analysis

Full Job Description

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.

Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.

Legend Biotech is seeking a Molecular Biology Scientist/Senior Associate Scientist as part of the Research & Early Development team based in Philadelphia, PA.

Role Overview

Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabta gene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of immunotherapy in the treatment of multiple myeloma.

Legend Biotech seeks a motivated molecular biologist to join the Vector Biology team in Philadelphia, supporting lentiviral vector (LVV) design, construction, and functional evaluation, as well as engineered cell line development to enable CAR-T and other cell therapy programs. This role emphasizes reliable experimental execution, timely delivery of materials, and clear data communication.

Key Responsibilities

Execute viral vector plasmid and helper plasmid design and construction to support gene overexpression, knock-down, and knock-out studies independently.
Perform routine molecular cloning workflows and ensure plasmid quality meets established QC standards for vector production.
Maintain accurate plasmid records including sequence files, maps, inventory/locations and support internal construct requests in partnership with other cross-functional teams.
Generate and characterize engineered mammalian cell lines for transient or stable viral vector production, single-cell cloning, cell engineering, and basic characterization.
Perform mammalian cell culture and transient transfection under BSL-2 conditions.
Support small-scale vector production using suspension cell lines for early development activities.
Execute molecular/cellular assays to evaluate vector performance using qPCR/dPCR, ELISA/Western Blot, and flow cytometry.
Analyze data, summarize results, present clear experiment conclusions, escalate issues, and propose next steps to project leads.
Adhere to BSL-2 biosafety standards and Legend policies, maintaining accurate and compliant electronic lab notebooks and documentation.
Collaborate cross-functional support tech transfer activities as needed.
Independently plans day-to-day execution within project goals, recommends optimizations and next experiments.

Requirements

Scientist: M.S. with 5+ years or Ph.D. with 0-2 years in a related field; hands-on molecular cloning, cell engineering and mammalian cell culture required.
Hands-on experience in molecular biology techniques (cloning, plasmid prep, sequence analysis and construct verification).
Experience with mammalian cell culture and transient transfection; familiarity with BSL-2 practices and documentation.
Experience generating engineered cell lines (stable expression and/or CRISPR KO/KI) including cloning and basic screening (Scientist preferred).
Exposure to viral vector production and/or viral vector workflows (LVV preferred).
Experience with titering and functional readouts (e.g., transduction efficiency and gene expression).
Experience with qPCR/dPCR, flow cytometry, Western blot, and ELISA for tittering and functional assays.
Strong ELN documentation, sample tracking, and ability to follow protocols/SOPs with attention to detail.
Adaptable to a fast-paced environment; effective prioritization, collaboration, and communication.
CRISPR/Cas gene editing for KO/KI or multiplexed cell lines.
Familiarity with viral vector process development concepts (upstream and/or downstream).
Exposure to NGS or Nanopore sequencing for vector or genome characterization.
Tech transfer and/or CMC documentation experience (nice to have).
Organized and detail-oriented; able to manage multiple experiments/projects.
Analytical and problem-solving skills to troubleshoot and implement improvement.
Collaborative; able to work effectively within a team environment.
Maintain accurate ELN, sample tracking, and inventory records.
Clear written and verbal communication for documentation and data presentation.

#Li-JR1

#Li-Onsite

Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.

EEO Statement

It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.

Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.

For information related to our privacy notice, please review: Legend Biotech Privacy Notice.

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Refine Your Search

senior scientist jobs in ridley park, pa

Molecular Biology Scientist/Senior Associate Scientist

Senior Clinical Scientist

Senior Director, Oncology Pharmacology

Senior Officer, Philadelphia Research and Policy Initiative

Senior Validation Scientist

FSP Senior Scientist, Biomarkers

FSP Senior Research Scientist-Dissolution Method Development

Senior Scientist

Senior Scientist, Biology-Discovery

Scientist/Senior Scientist - Cell Bioassay/Potency

Senior Scientist- Biologics

Senior Health Research Analyst

Scientist Senior

Senior Scientist, Bioanalytics

Research Scientist/Senior Research Scientist (Flow Chemistry)

Senior Research Coordinator

Senior Scientist Analytical Services

Senior Epidemiologist, Research and Evaluation

Senior Scientist, Product Development

Senior Director Clinical Research Scientist

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