Top 10 Senior software engineer hybrid Jobs in Rochester, Mn

Senior Software Engineer - AI Platform Engineering
Mayo Clinic —Rochester, MN
- $141,024 - $204,526 a year
- Full-time
- Azure
- Computer Science
- 5 years
- Health savings account
- Health insurance
2d
IT Cloud Engineer - Cloud Platform Engineering
Mayo Clinic —Rochester, MN
- $112,819 - $157,955 a year
- Full-time
- Remote
- Azure
- System design
- HIPAA
- Health savings account
- Health insurance
Senior IT/OT Network Engineer
Wunderlich-Malec Engineering, Inc —Eden, MN
- $85,000 - $125,000 a year
- Full-time
- Hybrid work
- Computer Science
- Up to 50% travel
- Office
- Travel reimbursement
- Profit sharing
Quick Apply
Senior IT/OT Network Engineer
Wunderlich-Malec Engineering, Inc. —Eden, MN
- $85,000 - $125,000 a year
- Full-time
- Hybrid work
- Computer Science
- Up to 50% travel
- Office
- Travel reimbursement
- Profit sharing
Principal Data Engineer - AI Program
Mayo Clinic —Rochester, MN
- $155,500.80 - $225,492.80 a year
- Full-time
- 7 years
- Azure
- Computer Science
- Health savings account
- Health insurance
9d
HTM Information Security Engineer
Mayo Clinic —Rochester, MN
- $102,336 - $143,270 a year
- Full-time
- Hybrid work
- Computer Science
- System design
- Laboratory experience
- Health savings account
- Health insurance
Principal Technical Lead
Knipper HEALTH —United States
- $130,000 - $160,000 a year
- Full-time
- Computer science
- Computer Science
- HIPAA
- Paid parental leave
- Health insurance
AI/ML Engineer
CGI Group, Inc. —United States
- $102,000 - $251,100 a year
- Azure
- Computer Science
- Office
- Paid parental leave
- Paid holidays

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IT Cloud Engineer - Cloud Platform Engineering
Mayo Clinic —Rochester, MN
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IT Senior Cloud Engineer - Product Operations Lead Cloud Services
Mayo Clinic —Rochester, MN
Working knowledge of the practical application of engineering and technology including applying principles, techniques, procedures, hardware and tools to the…
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Bachelor's degree in computer science or related technical field, or equivalent practical experience. Developer Tools: Familiarity with tools and platforms…
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Senior Software Engineer - AI Platform Engineering

Mayo Clinic -
Rochester, MN

Apply Now

Job Details

Full-time
$141,024 - $204,526 a year
2 days ago

Benefits

Health savings account
Health insurance
Dental insurance
Flexible spending account
Vision insurance
Opportunities for advancement

Qualifications

Version control
Software engineering
Engineering development testing
Writing skills
System design
System design for system development
Technical solutions implementation
Programming languages
Systems engineering
Software testing
Agile software development
Design (software development lifecycle)
Providing code feedback

Full Job Description

CityRochester

StateMN

RemoteNO

DepartmentInformation Technology

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights

Medical: Multiple plan options.
Dental: Delta Dental or reimbursement account for flexible coverage.
Vision: Affordable plan with national network.
Pre-Tax Savings: HSA and FSAs for eligible expenses.
Retirement: Competitive retirement package to secure your future.

Responsibilities

The Role

As a Senior Software Engineer for AI Platform Engineering, you will bridge the gap between high-scale systems architecture and frontier AI. You will be one of architects and builders of our Model & Agent Runtimes—the specialized engines that govern how models and autonomous agents execute across our hybrid-cloud footprint.

This isn't just about deployment; it’s about a platform-first mindset. You will ensure that AI capabilities are scalable, secure, and governed through world-class AgentOps, LLMOps, and MLOps practices.

What You’ll Do

Architect the Future of Runtimes: Design and implement high-performance hosting environments for both specialized models and autonomous agents.
Scale Hybrid-Cloud Infrastructure: Build multi-tenant platform capabilities that support seamless agent and model execution across diverse cloud and on-prem environments.
Drive Operational Excellence: Implement robust solutions for real-time monitoring, distributed tracing, and automated evaluation of agents & models in production.
Operational Stewardship: Act as a member of our rotational platform operational team, ensuring the reliability and uptime of critical AI services.
Collaborate & Advocate: Partner with cross-functional AI teams to identify system friction, streamlining their workflows and accelerating the delivery of AI-driven value.

What You’ll Bring

Deep Systems Expertise: Proven experience building scalable back-end systems, ideally with a focus on containerization and orchestration (Kubernetes).
AI/ML Fluency: Strong understanding of the lifecycle of LLMs and autonomous agents, including inference optimization and RAG architectures.
Operational Rigor: A track record of implementing observability (logging, metrics, tracing) in complex, distributed environments.
Problem-Solving Mindset: The ability to turn abstract AI research into production-grade, hardened platform features.

Why this team? We are moving beyond simple model serving. We are building the foundational "nervous system" for autonomous agents in a high-stakes environment where performance and governance are non-negotiable.

This vacancy is not eligible for sponsorship/ we will not sponsor or transfer visas for this position. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.

Qualifications

Required qualifications for this position include: Bachelor's Degree in Computer Science/Engineering or related field with 5 years of experience as noted below; OR an Associate’s degree in Computer/Science/Engineering or related field with 7 years of experience.

Have in-depth knowledge of software engineering with experience coding applications or services in a high-level programming language, preferably Python, and a basic knowledge of related fields.
Demonstrated problem solving and time management skills. Possesses strong technical aptitude for designing and implementing software solutions. Experience with modern application development frameworks
Knowledge of professional software engineering practices & best practices for the full software development life cycle, including coding standards, code reviews, source control management, build processes, testing, and operations. Deep hands-on technical expertise, excellent verbal and written communication skills. Experience with Agile software development techniques.

Preferred qualifications for this position include:
Master's degree in Computer Science/Engineering or related field.
Ability to use a wide variety of open-source technologies and cloud-based services.
Experience writing software for the cloud (GCP, AWS, Azure).
Experience in databases, analytics, big data systems or business intelligence products.
Experience building high-performance, highly available and scalable distributed systems.
Experience developing software for healthcare related industries.

Exemption Status

Exempt

Compensation Detail

$141,024 - $204,526 / year

Benefits Eligible

Yes

Schedule

Full Time

Hours/Pay Period

80

Schedule Details

8 AM to 5PM CST, weekdays

International Assignment

No

Site Description

Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Recruiter

Shelly Weir

Apply Now

Refine Your Search

senior software engineer hybrid jobs in rochester, mn

Senior Software Engineer - AI Platform Engineering

IT Cloud Engineer - Cloud Platform Engineering

Senior IT/OT Network Engineer

Senior IT/OT Network Engineer

Principal Data Engineer - AI Program

HTM Information Security Engineer

Principal Technical Lead

AI/ML Engineer

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