Top 252 Train engineer Jobs in San Diego Ca

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Scientist, Protein Engineer
Trutino Biosciences —San Diego, CA
- Full-time
- Doctor of Philosophy
- Mentoring
- Senior level
Geographic Info Sys Programmer 2
UC San Diego —San Diego, CA
- $33.09 - $35.00 an hour
- Monday to Friday
- Hybrid work
- Background check
- Mid-level
- Bachelor's degree
8d
HPC Systems Engineer
UC San Diego —San Diego, CA
- $94,400 - $115,000 a year
- Overtime
- Hybrid work
- Background check
- System design
- Mid-level
Sr. WebKit Performance Engineer
Apple —San Diego, CA
- $175,000 - $308,500 a year
- Computer science
- Computer Science
- Bachelor of Science
- Employee stock purchase plan
- Health insurance
12d
DevOps & SDLC Engineer - AI Trainer
DataAnnotation —San Diego, CA
- $50 - $100 an hour
- Part-time
- Remote
- Writing skills
- English
- Mid-level
- Flexible schedule
Quick Apply
Backend QA Engineer - AI Trainer
DataAnnotation —San Diego, CA
- $50 - $100 an hour
- Part-time
- Remote
- Writing skills
- English
- Mid-level
- Flexible schedule
Quick Apply
Mechanical Engineer - AI Trainer
DataAnnotation —San Diego, CA
- From $60 an hour
- Part-time
- Remote
- English
- Mid-level
- Bachelor's degree
Quick Apply
Mechanical Design Engineer - AI Trainer
DataAnnotation —San Diego, CA
- From $60 an hour
- Part-time
- Remote
- English
- Mid-level
- Bachelor's degree
Quick Apply
Cost Optimization Analyst - FinOps
ASML —San Diego, CA
- $89,250 - $148,750 a year
- Full-time
- Hybrid work
- Azure
- 5 years
- Writing skills
- Paid holidays
- Dental insurance
DIS TECH - US Sales Lead / Account Manager (Flexible Level)
DIS Tech —San Diego, CA
- From $135,000 a year
- Full-time
- Hybrid work
- Engineering
- 3 years
- Travel
- Health insurance
- Dental insurance
Quick Apply
Assistant Chief Engineer: Full-Time
Rancho Valencia Resort & Spa —Rancho Santa Fe, CA
- $85,000 - $90,000 a year
- Weekends as needed
- Inventory management
- Mid-level
- 3 years
Quick Apply
Senior Manufacturing Engineer – Advanced Semiconductor Systems
ASML —San Diego, CA
- $102,375 - $153,563 a year
- Multiple hires
- 5 years
- Analysis skills
- Travel
- Paid holidays
- Dental insurance
Manager, Design Center
PASONA N A, INC. —San Diego, CA
- $115,000 - $167,684 a year
- Full-time
- Microsoft Excel
- Engineering
- English
- Paid holidays
- Health insurance
Intermediate R&D Engineer
Cesna Recruitment —San Diego, CA
- $100,000 - $140,000 a year
- Full-time
- Computer science
- Computer Science
- English
- Paid holidays
- Health insurance
Quick Apply
Senior Field Engineer
ABM Industries —San Diego, CA
- $60 - $75 an hour
- Overtime
- Clean driving record
- 5 years
- High school diploma or GED
Machine Engineer
APA —San Diego, CA
- $21 - $47 an hour
- Full-time
- Computer literacy
- Engineering
- English
- Health savings account
- Health insurance
Quick Apply
2d
Applications Engineer - Digital
Advantest America, Inc. —San Diego, CA
- $70,125 - $108,375 a year
- Full-time
- Computer Science
- Mid-level
- Java
- Health savings account
- Health insurance
Quick Apply
6d
Senior Manufacturing Engineer – Solid State Power Pulse Modules (SSPPM)
ASML —San Diego, CA
- $102,375 - $170,625 a year
- Full-time
- Microsoft Excel
- 5 years
- Analysis skills
- Paid holidays
- Dental insurance
General Manager
G B GROUP INC —San Diego, CA
- $150,000 - $200,000 a year
- Microsoft Outlook
- Customer service
- Engineering
Quick Apply
Distribution Engineering Supervisor
Leidos —California
- $73,450 - $132,775 a year
- Full-time
- Hybrid work
- Microsoft Outlook
- Bachelor of Science
- Engineering
- Flexible schedule
6d

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train engineer jobs near san diego ca

Scientist, Protein Engineer

Trutino Biosciences
San Diego, CA

Apply Now

Job Details

Full-time

Qualifications

Advanced cell culture techniques
DNA analysis
Protein analysis (analytical chemistry specialty)
Molecular cloning
Biochemical laboratory techniques
Doctor of Philosophy

Full Job Description

Trutino Biosciences is a research-driven biopharmaceutical company with a mission to restore immuno-balance in cancer patients by developing the next generation cytokine therapies that can safely activate tumor-fighting immune cells at the disease site without causing adverse side effects. Trutino’s proprietary On-Demand-Cytokine (ODC) platform technology enables the design of therapeutic candidates that can be systemically delivered in an inactive form and be locally activated directly at the tumor site, thereby avoiding the extreme toxicity of conventional cytokine therapies, and potentially improving efficacy either as a single agent or in combination with other treatment modalities.

We are seeking a highly motivated Research Scientist with strong protein production and engineering expertise, who can focus on driving innovative, new approaches in drug discovery. The successful applicant will have extensive background in recombinant protein expression and purification methods, protein characterization and protein engineering, and will be responsible for developing and manufacturing novel zytokine (inactive cytokines) and zymokine (inactive chemokines) therapeutic candidates based on Trutino’s On Demand Cytokine Platform technology.

This position requires deep technical knowledge, exceptional communication skills (both written and oral), and the ability to work on and move forward multiple projects simultaneously under minimal supervision. The successful candidate will be a strategic member in a fast-paced, collaborative research setting.

Duties

Contribute to the design and development of novel recombinant protein therapeutics.
Design/plan experiments, perform hands-on protein expression, purification, and analytical characterization of therapeutic candidates using standard techniques.
Perform small to mid-scale expression of recombinant proteins in transient eukaryotic expression systems (mammalian, insect)
Generate stable expression cell lines using cells such as HEK293 and CHO.
Protein Purification duties include: preparation and packing of chromatography columns, conducting low endotoxin chromatography, including operating analytical and preparative fast performance and high-pressure chromatography systems.
Analytical characterization duties include: running SDS-PAGE, endotoxin measurement, protein quantitation assays, FPLC, HPLC, Biacore, analytical SEC analysis.
Prepare and optimize formulation buffer for protein stability.
Optimize protein expression and modulate protein function through molecular engineering approaches and the design of protein variants.
Develop new protocols and troubleshoot existing protocols to optimize protein production/purification process.
Analyze, summarize, and present experimental results to internal and external scientists, share technical expertise with other colleagues, train and/or supervise other personnel, if needed.
Stay abreast of current industrial protein expression and purification technologies.
Publish findings in scientific journals and/or scientific meetings.

Qualifications

A PhD in Biochemistry, Biochemical Engineering, Chemical Engineering or related areas and post-doctoral experience of 3+ years is required.
A minimum of 2-3 years’ experience in recombinant protein engineering, expression and purification in either an academic, institutional or industrial setting.
Experience with transient expression of proteins in mammalian cell lines such as. Freestyle / Expi293 and CHO cells is required. Experience with other eukaryotic expression systems is a plus.
Experience with stable cell line generation for protein production is desirable.
Experience with affinity, IEX, hydrophobic and size-exclusion chromatography is required.
Extensive hands-on experience in the following areas is required: DNA manipulation and cloning, transformation/transfection, cell culture and analytical protein characterization.
Demonstrated productivity during graduate and/or post-doc training, with clear evidence of peer-reviewed publications in top tier journals.
Ability to organize and communicate complex data sets in a clear and concise manner.
Candidate should be hands-on with a pro-active attitude, a strong team player with excellent oral and written communication skills and with a demonstrated ability to move projects forward and plan next steps with minimal supervision.

Preferred Experience and Skills

Ability to actively contribute scientifically to immunotherapy drug discovery research programs, including identification and validation of novel targets.
Review scientific literature and stay abreast of discoveries in immunotherapy field.
Ability to represent research team and communicate goals/deliverables to senior management
Experience in mentoring and/or leading PhD level and non-PhD level scientists.
Industry experience highly preferred.

Trutino Biosciences is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Job Category: R&D

Job Type: Full Time

Job Location: United States - California - San Diego

Apply Now

Refine Your Search

train engineer jobs in san diego ca

Scientist, Protein Engineer

Geographic Info Sys Programmer 2

HPC Systems Engineer

Sr. WebKit Performance Engineer

DevOps & SDLC Engineer - AI Trainer

Backend QA Engineer - AI Trainer

Mechanical Engineer - AI Trainer

Mechanical Design Engineer - AI Trainer

Cost Optimization Analyst - FinOps

DIS TECH - US Sales Lead / Account Manager (Flexible Level)

Assistant Chief Engineer: Full-Time

Senior Manufacturing Engineer – Advanced Semiconductor Systems

Manager, Design Center

Intermediate R&D Engineer

Senior Field Engineer

Machine Engineer

Applications Engineer - Digital

Senior Manufacturing Engineer – Solid State Power Pulse Modules (SSPPM)

General Manager

Distribution Engineering Supervisor

I want to receive the latest job alert for train engineer in san diego ca

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