Top 17 Senior statistician Jobs in San Francisco, Ca

Senior Statistician, Early Development
Genentech —San Francisco, CA
- $136,900 - $254,200 a year
- Online Application
- 3 years
- Analysis skills
- Doctor of Philosophy
Senior Principal Statistician
Genentech —San Francisco, CA
- Online Application
- 11+ years
- Analysis skills
- Continuous improvement
Senior Data Scientist
Genentech —San Francisco, CA
- $156,200 - $290,200 a year
- Online Application
- Master's degree
- Analysis skills
- Continuous improvement
Senior Biostatistician
CareDx, Inc. —San Francisco, CA
- $124,000 - $155,000 a year
- Full-time
- 3 years
- Master's degree
- Analysis skills
- Commuter assistance
- Employee stock purchase plan
6d
Senior Manager, Clinical Trials
Natera —San Carlos, CA
- $141,300 - $176,600 a year
- Remote
- Bachelor's degree
- Organizational skills
- Contracts
- Commuter assistance
- Health insurance
Senior Clinical Research Associate
Natera —San Carlos, CA
- $99,400 - $124,200 a year
- Bachelor of Science
- HIPAA
- Analysis skills
- Commuter assistance
- Health insurance
Senior Research Associate
Karius —Redwood City, CA
- $88,200 - $102,900 a year
- Full-time
- 5 years
- Bachelor of Science
- Office
Quick Apply
Senior Principal Statistician, Early Development (Director Level)
Genentech —San Francisco, CA
- $171,600 - $318,600 a year
- Online Application
- 11+ years
- Machine learning
- Doctor of Philosophy
Sr Director, Biostatistics
Exelixis, Inc. —Alameda, CA
- $248,000 - $352,500 a year
- Email
- 11+ years
- Office
- Analysis skills
- Paid holidays
- Disability insurance
Senior Clinical Scientist, ECD
Natera —San Francisco, CA
- $142,800 - $178,500 a year
- Remote
- Medicine
- 6 years
- Analysis skills
- Commuter assistance
- Health insurance
Senior Manager, Biostatistics
Corcept Therapeutics —Redwood City, CA
- $165,150 - $242,820 a year
- Hybrid work
- Office
- Doctor of Philosophy
- Team management
Quick Apply
Senior Manager, Biostatistics
Iovance Biotherapeutics —San Carlos, CA
- $145,000 - $175,000 a year
- Remote
- 3 years
- Analysis skills
- Continuous improvement
Quick Apply
Senior Workday Platform Engineer
Natera —San Carlos, CA
- $128,800 - $161,050 a year
- HIPAA
- 8 years
- Senior level
- Commuter assistance
- Health insurance
Sr. Staff Biostatistician
CareDx, Inc. —San Francisco, CA
- $158,000 - $205,000 a year
- Full-time
- Remote
- Management
- 5 years
- Doctor of Philosophy
- Commuter assistance
- Employee stock purchase plan
Principal Software Engineer
Natera —San Francisco, CA
- $219,800 - $274,700 a year
- Full-time
- Azure
- System design
- AWS
- Commuter assistance
- Health insurance
Sr Statistical Advisor
Gilead Sciences —Foster City, CA
- $261,375 - $338,250 a year
- Full-time
- 11+ years
- Doctor of Philosophy
- Software development
- Health insurance
- Dental insurance
12d
Senior Scientist, IVD Product Development
Natera —San Carlos, CA
- $138,100 - $172,600 a year
- Bachelor of Science
- 3 years
- Bachelor's degree
- Commuter assistance
- Health insurance

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Senior Principal Statistician
Genentech —San Francisco, CA
The Statistician is a key member of the cross-functional study or molecule team, responsible for applying statistical expertise to the design, conduct, analysis…
Senior Principal Statistician, Early Development (Director Level)
Genentech —San Francisco, CA
The Early Development Senior Prinicpal Statistician is a critical partner in the design and analysis of exploratory clinical studies, applying statistical…
$171,600 - $318,600 a year

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Senior Statistician, Early Development

Genentech -
San Francisco, CA

Apply Now

Job Details

Full-time
$136,900 - $254,200 a year

Qualifications

Biostatistics-based research

Full Job Description

The Position

This role is in Early Development Biometrics (EDB), a core function within Product Development Data Sciences (PDD) that provides strategic leadership and scientific rigor across early clinical development at Roche. We partner across Biostatistics, Analytical Data Science, and Data Management to enable data-driven decision-making from first-in-human through proof-of-concept studies.

As trusted partners in early development, we design efficient and innovative clinical trials, apply rigorous statistical methods, and implement high-quality programming and analytical solutions to accelerate timelines, de-risk development, and increase the probability of technical success. Our integrated teams operate with agility and scientific depth, supporting exploratory analyses, early regulatory engagements, and complex data-generation needs across therapeutic areas. Together, we bring scientific rigor, technical innovation, and strategic insight to shape the future of early development and deliver better outcomes for patients.

Early Development Biometrics is also home to Methods Collaboration & Outreach (MCO), which enables the most impactful use of quantitative methodology across PDD through internal consultation, external collaboration, and continuous capability building; and Visual Analytics, which creates and maintains interactive dashboards that drive high-quality Medical Data Review (MDR) and safety signal detection, aligned with Risk-Based Quality Management (RBQM) principles and Critical-to-Quality (CtQ) endpoints.

The Opportunity

The Early Development Statistician is a critical partner in the design and analysis of exploratory clinical studies, applying statistical expertise to guide early-phase trial strategy, design, and interpretation. This role ensures scientific rigor while maintaining the flexibility needed for hypothesis generation and signal detection. Responsibilities include contributing to protocol design, developing statistical analysis plans, and analyzing complex, often high-dimensional data to inform early go/no-go decisions and regulatory interactions. The Statistician helps shape the early clinical narrative by ensuring data are robust, interpretable, and aligned with the evolving development strategy.

You independently lead statistical input into early phase clinical trial designs, ensuring alignment with scientific and translational objectives, for example first in human, dose escalation, proof of concept, or biomarker enriched studies, and you utilize innovative or adaptive methodologies where appropriate
You own the development and quality review of statistical deliverables including protocols, SAPs, and CRFs, with a focus on fit for purpose design that supports regulatory and internal decision making
You design and execute complex analyses, often involving PK PD modeling, exploratory biomarker data, or interim futility assessments, and you proactively identify potential data limitations or methodological challenges and implement solutions
You collaborate with study teams to align study timelines and deliverables, bringing a proactive mindset to evolving scientific priorities
You interpret and communicate results in context, clearly framing the clinical relevance and implications of early signals to influence go no go decisions, dose or regimen selection, and future trial design
You lead statistical contributions to CSRs and regulatory documents, for example IND updates and briefing packages, supporting early regulatory interactions and communications with internal governance bodies

Who You Are:

You hold an MSc or PhD in Statistics, Biostatistics, or a closely related quantitative field
You bring at least 3 years of relevant experience in clinical trial statistics in pharmaceutical, biotech, or CRO settings
You have demonstrated experience contributing to the design, analysis, and interpretation of clinical studies across different phases
You have a solid understanding of regulatory expectations and statistical methodologies for clinical development
You are proficient in SAS and or R and familiar with CDISC standards
You work autonomously and collaborate effectively in cross functional teams
You demonstrate independent thinking and make decisions based on sound principles
You demonstrate excellent strategic agility including problem solving and critical thinking, with agility that extends beyond the technical domain
You demonstrate respect for cultural differences when interacting with colleagues in the global workplace
You have excellent verbal and written communication skills in presentation and writing, with the ability to explain complex technical concepts in clear language

Preferred:

Proven experience working in cross-functional, global early development teams, including collaboration with Clinical Pharmacology, Translational Science, and Early Clinical Development functions.
Strong communication skills, with the ability to distill complex, exploratory, or model-based statistical methodologies into actionable insights for clinicians, program leads, and non-statistical stakeholders.
Direct experience supporting early-stage drug development (e.g., Phase I/II trials), with an understanding of the unique design and analysis needs of FIH, SAD/MAD, dose-finding, and proof-of-concept studies.
Ability to influence cross-functional decisions through clear articulation of data implications, and translate preliminary data into strategic development recommendations.
Demonstrated mentoring or leadership experience, particularly in guiding less experienced statisticians or cross-functional partners in early-phase strategy or methodology.
Familiarity with innovative statistical designs, such as adaptive trials, Bayesian frameworks, or model-informed drug development (MIDD), and their application in early clinical research.
You provide functional guidance and informal mentoring, supporting the development of less experienced colleagues in statistical techniques and the strategic application of methods in early phase settings
You lead or influence study level projects and contribute significantly to cross study initiatives, for example platform protocols and disease area strategies, driving consistency and innovation across early development programs

Relocation benefits are not available for this posting.

The expected salary range for this position based on the primary location of California is $136,900 - $254,200. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#PDDT

#PDDSSF

#EDB

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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Refine Your Search

senior statistician jobs in san francisco, ca

Senior Statistician, Early Development

Senior Principal Statistician

Senior Data Scientist

Senior Biostatistician

Senior Manager, Clinical Trials

Senior Clinical Research Associate

Senior Research Associate

Senior Principal Statistician, Early Development (Director Level)

Sr Director, Biostatistics

Senior Clinical Scientist, ECD

Senior Manager, Biostatistics

Senior Manager, Biostatistics

Senior Workday Platform Engineer

Sr. Staff Biostatistician

Principal Software Engineer

Sr Statistical Advisor

Senior Scientist, IVD Product Development

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