Top 52 Senior scientist Jobs in Simi Valley Ca

Senior Scientist
Amgen —Thousand Oaks, CA
- $127,121.75 - $171,988.25 a year
- Pass drug screening
- 3 years
- Bachelor's degree
- Disability insurance
- Health insurance
4d
Senior Principal Scientist
Amgen —Thousand Oaks, CA
- $168,392.65 - $227,825.35 a year
- Bachelor's degree
- Doctor of Philosophy
- Organizational skills
- Disability insurance
- Health insurance
Senior Scientist
PBS Biotech Inc —Camarillo, CA
- $131,533 - $168,900 a year
- Weekends as needed
- 7 years
- Doctor of Philosophy
- Product management
Quick Apply
Safety Pharmacology Senior Scientist
Amgen —Thousand Oaks, CA
- $129,228.90 - $174,839.10 a year
- Master's degree
- Bachelor's degree
- Continuous improvement
- Disability insurance
- Health insurance
Process Development Senior Scientist
Amgen —Thousand Oaks, CA
- $126,066.05 - $170,559.95 a year
- 3 years
- Bachelor's degree
- Doctor of Philosophy
- Disability insurance
- Health insurance
Senior Scientist – Functional Genomics
Amgen —Thousand Oaks, CA
- $127,121.75 - $171,988.25 a year
- 3 years
- Master's degree
- Bachelor's degree
- Disability insurance
- Health insurance
8d
Senior Scientist (Small Molecule, Synthetics)
Amgen —Thousand Oaks, CA
- $126,066.05 - $170,559.95 a year
- Medicine
- 3 years
- Bachelor's degree
- Disability insurance
- Health insurance
1d
Senior Clinical Research Coordinator - Hematology/Oncology
UCLA Health —Westlake Village, CA
- $93,927.51 - $151,099.73 a year
- Mid-level
- Analysis skills
- Bachelor's degree
1d
Process Development Senior Scientist - Synthetic Peptides, Oligonucleotides, ADCs
Amgen —Thousand Oaks, CA
- $126,066.05 - $170,559.95 a year
- 3 years
- Bachelor's degree
- Doctor of Philosophy
- Disability insurance
- Health insurance
Senior RNA Chemist – RNA Therapeutics
Amgen —Thousand Oaks, CA
- $123,777 - $167,463 a year
- Presentation skills
- Bachelor's degree
- Doctor of Philosophy
- Disability insurance
- Health insurance
Senior Associate (In Vivo)
Amgen —Thousand Oaks, CA
- $82,908.15 - $112,169.85 a year
- Mid-level
- Master's degree
- High school diploma or GED
- Disability insurance
- Health insurance
Process Development Sr Scientist
Amgen —Thousand Oaks, CA
- $126,066.05 - $170,559.95 a year
- Management
- Doctoral degree
- Office
- Disability insurance
- Health insurance
Senior Clinical Research Coordinator - Department of Medicine - Office of Research Administration
UCLA Health —Los Angeles, CA
- $93,927.51 - $151,099.73 a year
- Management
- Word processing
- Computer literacy
Process Development Senior Associate
Amgen —Thousand Oaks, CA
- $80,044.50 - $108,295.50 a year
- Mid-level
- Master's degree
- High school diploma or GED
- Disability insurance
- Health insurance
Senior Scientist, Drug Product Technologies
Amgen —Thousand Oaks, CA
- $126,066.05 - $170,559.95 a year
- Medicine
- Bachelor's degree
- Doctor of Philosophy
- Disability insurance
- Health insurance
2d
Manager / Sr. Manager, Clinical Operations - FSP West Region
Thermo Fisher Scientific —California
- $115,000 - $178,000 a year
- Full-time
- Remote
- English
- Business development
- Travel
- Commuter assistance
- Paid parental leave
Senior Scientist - Cardiometabolic Disorders
Amgen —Thousand Oaks, CA
- $127,121.75 - $171,988.25 a year
- Medicine
- Management
- 3 years
- Disability insurance
- Health insurance
Senior Clinical Research Coordinator - Hematology/Oncology (Santa Monica)
UCLA Health —Santa Monica, CA
- $93,927.51 - $151,099.73 a year
- Mid-level
- Analysis skills
- University
Senior Scientist - Translational Science Lab, Flow Cytometry
IQVIA —Valencia, CA
- $64,200 - $133,600 a year
- Full-time
- Mid-level
- Office
- Bachelor's degree
Sr. Scientist- PKDM-BA (Immunoassay)
Amgen —Thousand Oaks, CA
- $130,384.05 - $176,401.95 a year
- 3 years
- Analysis skills
- Bachelor's degree
- Disability insurance
- Health insurance

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Senior Scientist

Amgen -
Thousand Oaks, CA

Apply Now

Job Details

$127,121.75 - $171,988.25 a year
4 days ago

Benefits

Disability insurance
Health insurance
Dental insurance
Flexible spending account
Vision insurance
Retirement plan

Qualifications

Proteomics
Mass spectrometers (MS)
Technical troubleshooting support

Full Job Description

US - California - Thousand Oaks

JOB ID: R-242145 LOCATION: US - California - Thousand Oaks WORK LOCATION TYPE: On Site DATE POSTED: Aug. 17, 2026 CATEGORY: Research SALARY RANGE: 127,121.75USD -171,988.25 USD

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Sr Scientist

What you will do

Let’s do this. Let’s change the world.

We are seeking a motivated Senior Scientist in mass spectrometry–based proteomics to join our talented and collaborative team in Thousand Oaks, CA. In this vital role, you will deliver critical insights to support target identification and drug discovery, while advancing innovative proteomics platform technologies.

You will contribute to both pipeline advancement and screening platform innovation by developing and implementing cutting-edge, high-throughput proteomics approaches. This includes executing automated sample preparation and mass spectrometry analyses across a range of assays, as well as designing, optimizing, and continuously enhancing next-generation screening workflows and analytical platforms.

This role requires hands-on experience operating and troubleshooting high-throughput mass spectrometry systems. Your work will play a key role in enabling innovative drug screening strategies, accelerating discovery efforts, and strengthening pipeline support.

Design, develop, and optimize high-throughput mass spectrometry–based proteomics workflows and screening platforms to accelerate drug discovery
Execute automated sample preparation and LC-MS/MS analysis across a broad range of high-throughput proteomics assays
Collaborate closely with chemistry, biology, and disease area teams as a technical and scientific subject matter expert, contributing to data-driven decision-making
Perform data analysis and generate insights into mechanism of action, target engagement, and selectivity using proteomics approaches
Present research findings at internal and external meetings and effectively communicate plans, results, and analyses to cross-functional teams
Maintain accurate and organized documentation of experiments, protocols, and analyses

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Senior Scientist we seek is a scientifically driven, collaborative, and innovative proteomics expert.

Basic Qualifications:

Doctorate degree (PhD, PharmD, or MD) with relevant experience OR
Master’s degree and 4 years of directly related experience OR
Bachelor’s degree and 6 years of directly related experience

Preferred Qualifications:

Doctorate degree in proteomics, chemoproteomics, biochemistry, chemistry, or a related discipline
Strong track record in developing mass spectrometry–based proteomics assays, operating advanced platforms (e.g., Orbitrap Astral), and analyzing proteomics data
Experience with sample preparation miniaturization and automation platforms
3+ years of experience in the biotech or pharmaceutical industry
Demonstrated innovation in assay, method, or platform development
Strong quantitative and computational expertise in high-dimensional proteomics data analysis
Ability to work effectively in a highly integrated, collaborative team environment, with excellent organizational, verbal, and written communication skills, and a proven track record of producing reliable and reproducible results.
Knowledge of targeted protein degradation or E3 ligase biology is a plus

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Apply Now

Refine Your Search

senior scientist jobs in simi valley ca

Senior Scientist

Senior Principal Scientist

Senior Scientist

Safety Pharmacology Senior Scientist

Process Development Senior Scientist

Senior Scientist – Functional Genomics

Senior Scientist (Small Molecule, Synthetics)

Senior Clinical Research Coordinator - Hematology/Oncology

Process Development Senior Scientist - Synthetic Peptides, Oligonucleotides, ADCs

Senior RNA Chemist – RNA Therapeutics

Senior Associate (In Vivo)

Process Development Sr Scientist

Senior Clinical Research Coordinator - Department of Medicine - Office of Research Administration

Process Development Senior Associate

Senior Scientist, Drug Product Technologies

Manager / Sr. Manager, Clinical Operations - FSP West Region

Senior Scientist - Cardiometabolic Disorders

Senior Clinical Research Coordinator - Hematology/Oncology (Santa Monica)

Senior Scientist - Translational Science Lab, Flow Cytometry

Sr. Scientist- PKDM-BA (Immunoassay)

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careers.amgen.com

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