Required Application Materials
A single PDF or Word document containing a resume, letter of interest, and a list of the names and contact information for three (3) professional references is required to apply.
Important Instructions:
When prompted to upload your “resume”, upload your combined documents as one file.
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Please do not upload documents to “Cover Letter” or “References”.
If the required application materials were not uploaded at the “resume” prompt, please withdraw your application, and re-apply to upload your combined documents as one file.
Job Summary
The Research Technician will support a translational research program focused on lung (LUSC) and head and neck squamous cell carcinoma (HNSCC), extracellular vesicle (EV) biology, and cisplatin-resistance mechanisms. The technician will receive comprehensive training in cell culture, EV isolation, molecular assays, and drug-response workflows. This role is ideal for candidates seeking hands-on research experience and long-term skill development in a cancer biology laboratory.
Key Responsibilities
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Maintain LUSC and HNCC parental and resistant cell lines under BSL 2 conditions.
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Assist with EV isolation using ultracentrifugation and size exclusion chromatography.
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Perform basic molecular assays (Western blotting, qPCR) after training.
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Assist with IncuCyte live cell imaging experiments, including setting up plates, monitoring real time proliferation, migration, and apoptosis assays.
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Support 3D spheroid generation, maintenance, and drug response assays, including IncuCyte based spheroid imaging and quantification.
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Support drug response experiments, including viability and apoptosis assays.
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Prepare media, reagents, buffers, and EV related consumables.
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Record experimental observations accurately in electronic lab notebooks.
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Assist in organizing data for future grants.
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Maintain reagent logs, EV production records, and inventory databases.
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Help maintain a clean, organized, and efficient workspace.
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Monitor inventory and assist with ordering reagents and consumables.
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Support equipment maintenance and calibration schedules.
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Work closely with the PI and senior researchers to learn new techniques.
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Participate in lab meetings and contribute to project discussions.
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Assist in training new students once proficient.
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Other duties as assigned.
Required Education/Experience
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Bachelor’s degree in microbiology, Molecular Biology, Biochemistry, or a related field.
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Prior exposure to cell culture, molecular biology, or imaging-based assays (e.g., IncuCyte) is helpful but not mandatory.
Accompanying Knowledge, Skills, Abilities and Competencies
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Strong organizational and problem-solving skills with the ability to multitask and manage laboratory operations.
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Excellent written and verbal communication skills.
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Ability to work independently and as part of a team.
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Previous experience in a research laboratory, particularly in cell culture and cell-based assays
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Experience with lab management, inventory control, and ordering laboratory supplies.
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Knowledge of biosafety and regulatory requirements for laboratory operations.
Working Environment
Laboratory and research environment.
About The University of Texas at Tyler and UT Tyler Health Science Center
The University of Texas at Tyler is part of the prestigious University of Texas System that includes 14 institutions located throughout the state. Founded in 1971, UT Tyler today enrolls 10,000 students and consists of six colleges.
Designated an R2 research institution by the Carnegie Classification of Institutions of Higher Education, UT Tyler supports our surrounding region through innovation intended to uplift communities, spearhead sustainability initiatives, preserve ecosystems and support entrepreneurship. UT Tyler has the highest Carnegie classification in East Texas.
Providing exceptional patient care, comprehensive education and innovative research, The University of Texas at Tyler Health Science Center and UT Health East Texas combine to serve as the university medical center for Northeast Texas and beyond.
For more information, please visit https://www.uttyler.edu/about.
Why work for UT Tyler? Find out more: Why Work for UT Tyler?
Additional Information
The retirement plan for this position is Teacher Retirement System of Texas (TRS), subject to the position being at least 20 hours per week and at least 135 days in length. This position has the option to elect the Optional Retirement Program (ORP) instead of TRS, subject to the position being 40 hours per week and at least 135 days in length.
This position is security-sensitive and subject to Texas Education Code Section 51.215, which authorizes the employer to obtain criminal history record information. Applicants selected must be able to show proof of eligibility to work in the United States by time of hire.
For more information regarding benefits offered by UT Tyler, please visit https://www.uttyler.edu/offices/human-resources/employees/benefits.
Clinical Position Requirements
Clinical positions require pre-screening through our Occupational Health department, including a drug test. Employees are required to obtain annual influenza vaccines.
EEO Statement
The University of Texas at Tyler is an Equal Employment Opportunity Employer.
