Required Application Materials
A single PDF or Word document containing a resume, letter of interest, and a list of the names and contact information for three (3) professional references is required to apply.
Important Instructions:
When prompted to upload your “resume”, upload your combined documents as one file.
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Please do not upload documents to “Cover Letter” or “References”.
If the required application materials were not uploaded at the “resume” prompt, please withdraw your application, and re-apply to upload your combined documents as one file.
Job Summary
The Postdoctoral Research Associate or Postdoctoral Research Associate Senior will join the PI’s efforts in understanding virus-host interactions with a focus on cell entry of HIV-1, SARS-CoV-2, or RSV. The position will perform in vitro experiments and/or computation and contribute to the laboratory research program.
The Postdoctoral Research Associate will organize, design, and perform experiments utilizing molecular biology, cell biology, virology, biophysical, and biochemical techniques or assays. The position will perform experiments in the laboratory, likely including mammalian cell cultures, generation of plasmid and viral vectors, transfections, neutralization, western blotting, molecular cloning, ligand-binding, fluorescent imaging, structural characterization of membrane-bound or soluble viral proteins, preparation of extracellular vesicles, and protein purification. The Postdoctoral Research Associate role will be filled according to the education, technical skills, direct relevant research experience, and qualifications of the selected candidate. This position may require work beyond normal working hours, including weekends.
Key Responsibilities
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Design and conduct experiments in biomedical research related to virus-host interactions.
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Collect and analyze data.
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Publish in peer-reviewed journals.
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Prepare abstracts, manuscripts for publication, and written reports of research, grant proposals, grant reports independently.
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Make scientific presentations and perform other work-related duties, as assigned.
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Run assays such as molecular cloning, Western Blots, qPCR, Flow Cytometry, ELISA, biomedical imaging, protein purifications, infectivity, neutralization, etc.
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Generate plasmids and viral vectors and perform virus transmissibility/evasion studies.
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Collaborate with other lab members and prioritize job duties according to the needs of the lab.
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Maintain lab notebooks and records, supplies, and samples in a well-organized and accurate manner.
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Attend scientific conferences at the discretion of the PI.
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Activities include performing all necessary biochemical, biophysical, molecular, virology, structural biology, and cell biology techniques to conduct the research.
- Responsible for daily record keeping and completing data analysis.
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Other duties and responsibilities as assigned.
Required Education/Experience
Postdoctoral Research Associate
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Ph.D. or equivalent degree.
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Two (2) years of experience in biomedical research.
Postdoctoral Research Associate Senior
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Ph.D. or equivalent degree.
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Three (3) years of experience in biomedical research, preferably in molecular virology, single-molecule biophysics, or biochemistry.
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Molecular Virology: Lentiviruses, coronaviruses, or other human viruses; molecular cloning, qPCR, western blot, live cell imaging, luciferase assays, FACS, co-IP, etc.
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Structural Biology: Protein expression/purification, crystallography, cryoEM, binding kinetics.
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Biophysical Imaging: Single-molecule FRET, super-resolution, single-particle tracking, TIRF, confocal microscopy. Programming skills preferred.
Accompanying Knowledge, Skills, Abilities and Competencies
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Demonstrates strong organizational and project management skills.
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Familiarity with initiating and maintaining mammalian cell cultures, virus infectivity/neutralization, lentiviral packaging technologies, generation of stable cell lines, and protein structural dynamics.
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Knowledge of lab skills including tissue culture, western blots, qPCR/RT-PCR, cell sorting/FACS, ELISA, SPR, protein purification, fluorescent microscopy, ELISA, lentiviral packaging, co-IP, etc.
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Demonstrates excellent lab knowledge, adaptability, decision-making, problem-solving, informing, and communication skills and positively maintaining professional and lab relationships.
- Knowledge about statistical methods and protein biochemistry.
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Ability to follow oral instructions and laboratory rules.
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Remains accountable and willing to accept supervision and work well with others.
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Remains in compliance with all institutional training and code of conduct.
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Ability to work independently based on experience.
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Knowledge of molecular dynamics simulation and mathematical modeling.
Working Environment
Laboratory and research environment.
About The University of Texas at Tyler and UT Tyler Health Science Center
The University of Texas at Tyler is part of the prestigious University of Texas System that includes 14 institutions located throughout the state. Founded in 1971, UT Tyler today enrolls 10,000 students and consists of six colleges.
Designated an R2 research institution by the Carnegie Classification of Institutions of Higher Education, UT Tyler supports our surrounding region through innovation intended to uplift communities, spearhead sustainability initiatives, preserve ecosystems and support entrepreneurship. UT Tyler has the highest Carnegie classification in East Texas.
Providing exceptional patient care, comprehensive education and innovative research, The University of Texas at Tyler Health Science Center and UT Health East Texas combine to serve as the university medical center for Northeast Texas and beyond.
For more information, please visit https://www.uttyler.edu/about.
Why work for UT Tyler? Find out more: Why Work for UT Tyler?
Additional Information
The retirement plan for this position is Teacher Retirement System of Texas (TRS), subject to the position being at least 20 hours per week and at least 135 days in length.
This position is security-sensitive and subject to Texas Education Code Section 51.215, which authorizes the employer to obtain criminal history record information. Applicants selected must be able to show proof of eligibility to work in the United States by time of hire.
For more information regarding benefits offered by UT Tyler, please visit https://www.uttyler.edu/offices/human-resources/employees/benefits.
Clinical Position Requirements
Clinical positions require pre-screening through our Occupational Health department, including a drug test. Employees are required to obtain annual influenza vaccines.
EEO Statement
The University of Texas at Tyler is an Equal Employment Opportunity Employer.
