Top 2 Senior chemist Jobs in Utah

Senior Manager, QC Chemistry
Denali Therapeutics —Salt Lake City, UT
- Bachelor of Science
- 3 years
- Analysis skills
- Employee stock purchase plan
- Health insurance
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Senior Manager, QC Chemistry

Denali Therapeutics -
Salt Lake City, UT

Apply Now

Job Details

Benefits

Employee stock purchase plan
Health insurance
401(k)

Qualifications

Data integrity assurance
Document control experience within pharmaceutical industry
High-performance liquid chromatographs
Chemist team management
Data quality management
Biochemical laboratory techniques
Bachelor's degree
Pharmaceutical company experience
Pharmaceutical analysis
Quality control experience within pharmaceutical industry
Senior leadership

Full Job Description

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.

We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.

The Senior Manager, QC Chemistry will serve as both a technical and people leader within the QC Chemistry group, overseeing up to 5 chemists responsible for analytical testing of biologics and related materials. This individual will ensure the delivery of safe, compliant, and on-time analytical results at scale. This is a hands-on leadership role with routine lab work (approximately 40–60%, workload-dependent) required to support critical testing, troubleshooting, and method lifecycle activities.

The ideal candidate will play a key role in supporting both clinical and commercial readiness by ensuring phase-appropriate method performance, data integrity, and operational excellence across all testing activities, with a strong emphasis on chromatography-based methods.

Key Accountabilities/Core Job Responsibilities :

Lead and develop QC Chemistry team; set priorities, build schedules, run tier huddles, and ensure coverage/cross-training
Hands-on (~50%) lab leader supporting chromatography testing, troubleshooting, record approvals, and bench mentoring
Own analytical method lifecycle (readiness, validation/verification/transfer); author/review protocols, reports, and change control
Serve as QC SME for HPLC/UPLC and core analytical techniques (e.g., UV/Vis); support biologics assays (e.g., CE-SDS, icIEF, potency) as needed
Ensure GMP/ALCOA+ data integrity & GDP; review/approve ELN/LIMS entries; maintain audit readiness and responses
Lead OOT/OOS/deviation investigations, root cause, and CAPAs; verify effectiveness and drive timely closure
Act as QC lead for method transfers, coordinating with AD/CMC/Manufacturing; define readiness and execute in QC
Oversee instrument lifecycle (URS inputs, IOQ/PQ, calibration/PM, training, release-to-use) with ENG/vendors
Drive operations & KPIs (TAT, investigation cycle time, schedule adherence); standardize SOPs/templates and oversee routine QC testing, stability, and sample management
Lead direct report(s) through goal setting, development planning, training compliance, and ongoing performance feedback

Qualifications/Skills :

Typically requires a BS in Chemistry, Biochemistry, or related field and 8+ years of GMP QC experience (pharma/biotech), including 3+ years of people management experience
Strong hands-on chromatography experience (HPLC/UPLC required)
Prior experience leading or mentoring small teams
Experience with analytical method validation, transfer, and troubleshooting
Strong knowledge of GMP, data integrity (ALCOA+), and QC documentation practices
Experience with OOS/OOT investigations, root cause analysis, and CAPAs
Familiarity with CDS/ELN/LIMS systems (e.g., Empower, OpenLab)
Biologics analytical experience (e.g., CE-SDS, icIEF, potency) is a plus, not required
Ability to work onsite in Salt Lake City, UT with occasional off-shift support

Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at https://www.denalitherapeutics.com/careers

This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.

Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

Salt Lake City Drug Testing Policy

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senior chemist jobs in utah

Senior Manager, QC Chemistry

Sr. Manager Lab Operations - Analytical Chemistry

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I want to receive the latest job alert for senior chemist in utah

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Lead and develop QC Chemistry team; set priorities, build schedules, run tier huddles, and ensure coverage/cross-training

Hands-on (~50%) lab leader supporting chromatography testing, troubleshooting, record approvals, and bench mentoring

Own analytical method lifecycle (readiness, validation/verification/transfer); author/review protocols, reports, and change control

Serve as QC SME for HPLC/UPLC and core analytical techniques (e.g., UV/Vis); support biologics assays (e.g., CE-SDS, icIEF, potency) as needed

Ensure GMP/ALCOA+ data integrity & GDP; review/approve ELN/LIMS entries; maintain audit readiness and responses

Lead OOT/OOS/deviation investigations, root cause, and CAPAs; verify effectiveness and drive timely closure

Act as QC lead for method transfers, coordinating with AD/CMC/Manufacturing; define readiness and execute in QC

Oversee instrument lifecycle (URS inputs, IOQ/PQ, calibration/PM, training, release-to-use) with ENG/vendors

Drive operations & KPIs (TAT, investigation cycle time, schedule adherence); standardize SOPs/templates and oversee routine QC testing, stability, and sample management

Lead direct report(s) through goal setting, development planning, training compliance, and ongoing performance feedback

Typically requires a BS in Chemistry, Biochemistry, or related field and 8+ years of GMP QC experience (pharma/biotech), including 3+ years of people management experience

Strong hands-on chromatography experience (HPLC/UPLC required)

Prior experience leading or mentoring small teams

Experience with analytical method validation, transfer, and troubleshooting

Strong knowledge of GMP, data integrity (ALCOA+), and QC documentation practices

Experience with OOS/OOT investigations, root cause analysis, and CAPAs

Familiarity with CDS/ELN/LIMS systems (e.g., Empower, OpenLab)

Biologics analytical experience (e.g., CE-SDS, icIEF, potency) is a plus, not required

Ability to work onsite in Salt Lake City, UT with occasional off-shift support

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