Tosoh Bioscience LLC is a major supplier of chromatography products to the pharmaceutical, biotechnology, and chemical industries. Our product line includes:TSKgel, TOYOPEARL, and Ca++Pure-HA bulk media, TSKgel U/HPLC columns, process development products, dedicated systems for GPC analysis, and the LenS3 MALS detector. We have optimal solutions for biological research, drug discovery, medicinal chemistry, agriculture, manufacturing, or other industrial applications.
Summary
The major objective of this co-op position (under close supervision of a scientist) is to develop and optimize methods for packing resins into a variety of chromatography supports which will be commercialized for purification and analysis of biopharmaceuticals. The target biopharmaceuticals (aka biologics) include therapeutic proteins and nucleic acids used in cell and gene therapy. These biologics have become immensely important in the treatment of various chronic diseases such as rheumatoid arthritis, cancer, and infectious diseases. During the internship, the co-op student will learn laboratory and other skills described in this job profile.
Reporting Relationships
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Reports to the Research & Development Scientist – Column Technologies.
Major Duties and Responsibilities
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types and size supports. This includes preparing the resin, assembling the chromatography hardware, preparing solutions used in packing the columns, packing the chromatography column under variable conditions, and testing the performance of the column (ie. Asymmetry, theoretical plates, etc) following packing.
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Other areas of research may include experiments to further characterize column performance including shelf-life stability studies, scale up, binding capacity, etc.
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Conduct experiments and provide data, analyze results, and prepare reports in a timeline driven process and contribute to the efficient operation of R&D laboratories.
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Learn the fundamentals of column chromatography in all the various modes and how they are used to achieve purification of a target.
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Exercise technical judgment in the design, execution, and interpretation of experiments, and use professional concepts to solve complex problems in creative and effective ways.
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Maintain a laboratory notebook and other technical documentation according to required guidelines.
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This is a laboratory-based position and, thus, anyone working in this environment will comply with all required training, and maintain a focused attention on laboratory safety for themselves and a team.
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Maintain regular and reliable attendance.
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Uphold and adhere to the Tosoh Bioscience culture and guiding principles.
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Other duties as required.
Skills and Qualifications
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Basic knowledge of laboratory work, such as pipetting, buffer preparations, and use of standard laboratory instruments. Training will be provided.
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Excellent writing skills to maintain laboratory notebook and to prepare technical reports.
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Highly motivated individual that can exhibit an attention to detail.
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Strong communication skills (written and verbal). Further training in presenting lab results in team and departmental meetings will be provided.
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Knowledge and experience with Microsoft Office software, as well as intermediate to advanced software skills with PowerPoint and Excel.
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Strong analytical and problem-solving skills, and able to think creatively.
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Able to learn quickly and work independently under general direction.
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Responsible for mature attitude, teamwork, and time management.
Physical Requirements
The physical demands of this job are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
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While performing the duties of this job, the employee is regularly required to stand, walk, sit, and talk or hear.
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The employee is frequently required to reach with hands and arms and make precisely coordinated movements of the fingers of one or both hands to grasp, manipulate, or assemble very small objects.
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The employee is occasionally required to climb and balance.
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Specific vision abilities required by this job include close vision.
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Requires the ability to lift to mid-chest 30 pounds or carry up to 25 pounds.
Tosoh Bioscience LLC is an Equal Opportunity Employer M/F/Disabled/Veterans
