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Senior Research Scientist, Protein Chemistry

ICON Plc -
Wilmington, DE

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Job Details

Full-time
$78,000 a year
2 days ago

Benefits

Disability insurance
Health insurance
Dental insurance
Pension plan
Employee assistance program
Vision insurance

Qualifications

Molecular Biology
Biochemistry
Teamwork
Protein analysis (analytical chemistry specialty)
Handling antibodies
Master's degree
Biochemical laboratory techniques
Chemical separation processes
Doctor of Philosophy
Pharmaceutical analysis

Full Job Description

At ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON’s global expertise. As the world’s largest FSP organization, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide.

Join ICON as a Senior Research Scientist, Protein Chemistry and play a key role in the design, expression, purification, and characterization of recombinant proteins and antibodies supporting drug discovery and development programs.

Location: Wilmington, Delaware

What You'll Do

Design and optimize recombinant protein constructs for expression and downstream applications.
Perform protein expression using mammalian, insect (Sf9), and bacterial systems.
Generate baculovirus, conduct mammalian cell transfections, and maintain cell lines.
Develop and execute protein purification workflows using chromatography techniques including affinity, ion exchange, hydrophobic interaction, and size exclusion chromatography (SEC).
Purify and characterize antibodies, antibody fragments, and antibody-containing complexes.
Perform analytical and quality control assessments including protein purity, aggregation, integrity, and concentration.
Characterize proteins using biophysical and biochemical techniques such as SEC-HPLC, SDS-PAGE, DSF, BLI, SPR, and mass analysis.

What We're Looking For

Required Qualifications

PhD in Biochemistry, Biophysics, Protein Chemistry, Molecular Biology, Structural Biology, or related field with 2+ years of relevant experience, or Master's degree with 5+ years of relevant experience in biotechnology, pharmaceutical research, drug discovery, or academic laboratory research.
Hands-on expertise in recombinant protein expression, purification, and characterization.
Strong experience with chromatography-based purification methods, including affinity, ion exchange, and SEC.
Experience with analytical and biophysical characterization techniques such as SEC-HPLC, DSF, BLI, and SPR.
Proven experience purifying and characterizing antibodies and antibody fragments.

Preferred Experience

Biotherapeutics or drug discovery research experience.
Experience developing and optimizing protein purification workflows.
Strong problem-solving skills and ability to work independently in a fast-paced research environment.

If you are passionate about protein science and advancing innovative therapies, we'd love to hear from you. Apply today to join ICON's scientific team.

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.

Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.

Benefits may include:

Competitive base salary and performance related incentives
Health and well-being programs including medical, dental, and vision coverage where applicable
Retirement and pension plans
Life assurance and disability coverage
Employee assistance programs and wellbeing resources
Learning and development opportunities through structured training and career pathways

Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.

If you require reasonable accommodation during the recruitment process, please let us know or submit a request.

Pay: $78,000.00 per year

People with a criminal record are encouraged to apply

Work Location: In person

Quick Apply

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