Top 147 Senior scientist, oligonucleotide chemist Jobs in Novato, Ca

Senior Scientist, Oligonucleotide Chemist
LGC Group —Petaluma, CA
- $120,000 - $145,000 a year
- Full-time
- English
- Master's degree
- Analysis skills
Quick Apply
Senior Hazards/Hazardous Materials Analyst
Aspen Environmental Group —California
- $125,000 - $150,000 a year
- Email
- Microsoft Excel
- 11+ years
- Master's degree
Quick Apply
Senior Research Associate, Lipid Nanoparticle Formulation
Yoh, A Day & Zimmermann Company —San Francisco, CA
- $42 - $60 an hour
- Contract
- Master's degree
- Fair chance
- Senior level
- Health savings account
- Disability insurance
Quick Apply
9d
Senior Scientist, Process Chemistry
Merck —San Francisco, CA
- $131,400 - $206,800 a year
- Full-time
- Doctor of Philosophy
- Travel
- Fair chance
- Paid holidays
- Health insurance
4d
Sr Scientist/Principal Scientist, Discovery Oncology (in vivo Biology)
Eli Lilly —San Francisco, CA
- $71,250 - $187,000 a year
- Full-time
- Bachelor of Science
- Bachelor's degree
- Mentoring
- Health insurance
- Dental insurance
12d
Senior Scientist I/II, Analytical Chemistry
Pacific BioLabs —Hercules, CA
- $115,000 - $135,000 a year
- Urgently hiring
- 5 years
- Research
- Analysis skills
- Dental insurance
- 401(k)
(Senior) Scientist, Stem Cell
Conception —Berkeley, CA
- Full-time
- Research
- Doctor of Philosophy
- Senior level
- Health insurance
Senior Algorithm Scientist
Oura —San Francisco, CA
- $172,550 - $203,000 a year
- Hybrid work
- Office
- 3 years
- Doctor of Philosophy
- Paid holidays
- Health insurance
Principal Chemist
LGC Group —Petaluma, CA
- $131,155 - $196,733 a year
- Full-time
- 11+ years
- Continuous improvement
- Doctor of Philosophy
Quick Apply
Senior Research Scientist
Pixar Animation Studios —Emeryville, CA
- $219,980 - $284,680 a year
- 7 years
- Computer Science
- Doctor of Philosophy
Senior Data Scientist
Merck —San Francisco, CA
- $159,600 - $251,200 a year
- Full-time
- Computer Science
- Master's degree
- Math
- Paid holidays
- Health insurance
3d
Forensic Computer Analyst SR
U.S. Postal Service —Richmond, CA
- $128,740 - $178,390 a year
- Online Application
- Hybrid work
- Computer Science
- Pass drug screening
- Bachelor's degree
- Flextime
- Life insurance
Senior Scientist, Antibody Discovery
Merck —San Francisco, CA
- $131,400 - $206,800 a year
- Full-time
- Master's degree
- Analysis skills
- Bachelor's degree
- Paid holidays
- Health insurance
(Senior) Research Associate, Stem Cell Biology
Conception —Berkeley, CA
- Full-time
- Research
- Bachelor's degree
- 1 year
Scientist/Senior Scientist, Stem Cell/iPSC Research–Foster City, CA (San Francisco Bay Area)
Illumina —San Francisco Bay Area, CA
- $113,300 - $169,900 a year
- Full-time
- Background check
- Bachelor of Science
- Bachelor's degree
- Dental insurance
- Paid time off
3d
Scientist II/Senior Scientist, Computational Chemistry, Drug Discovery
Lila Sciences —San Francisco, CA
- $140,800 - $217,800 a year
- Doctor of Philosophy
- Senior level
- Python
Quick Apply
12d
Senior Clinical Scientist, ECD
Natera —San Francisco, CA
- $142,800 - $178,500 a year
- Remote
- Medicine
- 6 years
- Analysis skills
- Commuter assistance
- Health insurance
Senior Field Scientist
Alembic —San Francisco, CA
- $160,000 - $185,000 a year
- Full-time
- AWS
- Travel
- Mentoring
Senior Research Scientist
Sciforium —San Francisco, CA
- $190,000 - $250,000 a year
- Full-time
- Computer Science
- 5 years
- Doctor of Philosophy
- Health insurance
- Dental insurance
Decision Scientist Senior
Salesforce —San Francisco, CA
- $148,500 - $223,900 a year
- Full-time
- Computer Science
- 5 years
- Mentoring
- Paid parental leave
- Disability insurance
13d

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Senior Scientist, Oligonucleotide Chemist

LGC Group -
Petaluma, CA

Quick Apply

Job Details

Full-time
$120,000 - $145,000 a year

Qualifications

Implementing manufacturing quality control protocols
Automation
English
Biochemical laboratory techniques
Chemical separation processes
Pharmaceutical analysis
Laboratory compliance
Laboratory quality control
Mass spectrometers (MS)
Data-driven problem-solving
Research data analysis
Industrial research
GMP for research safety and compliance
Handling nucleic acids
Molecular analysis

Full Job Description

Company Description

ABOUT LGC BIOSEARCH TECHNOLOGIES:

With manufacturing sites across the US, UK, Germany and Denmark, LGC Biosearch Technologies has plans to continue growing. We deliver mission critical genomics to our diverse customer base in molecular diagnostics, pharma/biotech and agrigenomics. Our integrated portfolio of products, services and expertise supports our purpose of Science for a Safer World and we have embodied our mission by working with customers to enable research into life-altering treatment for disease and illness worldwide. We are currently seeking candidates who are up for the challenge of operating in a high-growth, purpose-driven organisation.

Job Description

The role of an Senior Scientist, Oligonucleotide Chemist within the Innovation Hub team in Petaluma, CA, USA. Is to develop and / or improve synthesis, deprotection, purification, modification, and analysis methods and processes to enable the introduction of new oligonucleotide related products and the transfer of these into manufacturing.

Ensure compliance with safety regulations and Quality Management policies and processes.
Is the Technical Lead in Oligonucleotide NPD and / or custom / co-creation projects.
Collaborate with multidisciplinary teams to support both IH and Operations project deliverables.
Core function is to act as the technical oligonucleotide chemistry lead and contribute to the development and delivery of new oligonucleotide-based technologies and applications
Demonstrated ability to independently design, project plan and execute development projects.
Independently develop synthesis methods to enable the delivery of custom / co-creation / NPD oligonucleotides using automated synthesizers and manual techniques.
Independently develop and optimize methods for oligonucleotide modification and conjugation (on-column and post synthesis and deprotection).
Independently develop and optimize purification methods for various modified oligonucleotides and conjugates.
Perform analytical characterization of oligonucleotides using HPLC, mass spectrometry, and other relevant techniques.
Troubleshoot synthesis, deprotection and purification processes to resolve manufacturing issues and / or improve yield and quality.
Independently generate documentation package to support operations effective control and transfer into manufacturing
Act as the subject matter expert post tech transfer and assist with chemistry troubleshooting.
Maintain accurate records of experiments and results in accordance with laboratory protocols
Prepare technical reports and present findings to internal and external stakeholders. Effective communication at all business and technical levels.

Qualifications

Master's degree in chemistry or a relevant field plus a minimum of 10 years industrial experience in modified oligonucleotide chemistry or demonstrated equivalence.
Extensive knowledge and in lab practice with oligonucleotide chemistries, protocols and analysis. Demonstrated experience in synthesis, deprotection, purification, post synthesis conjugation techniques and analysis/characterization of oligonucleotides.
- Proven expertise in using automated synthesizers and manual synthesis methods. Ideally with experience in a variety of synthesis platforms such as, but not limited to, MerMade, Dr Oligo, Shasta, K&A, OligoMaker, AKTA.
- Full comprehension of all steps within the synthesis cycle and impact of changes to methods, cycle times and reagents to the fit, form and function of the oligonucleotide. Seasoned ability to predict oligonucleotide impurity profiles resulting from processing changes
- Full comprehension of all deprotection schemes and resulting chemical conformations and degradation products.
- Full comprehension of non-compatible chemistry within the oligo and in subsequent processing.
- Full comprehension of oligonucleotide purification chemistries
Proficiency in analytical techniques, particularly HPLC and mass spectrometry.
Demonstrated extensive problem-solving experience.
Ability to optimize complex chemical processes and adapt to shifting priorities in a fast-paced, quality-driven environment.
Ability to make data driven recommendations and decisions.
Excellent data analysis and interpretation abilities
Experience with quality control procedures and GMP regulations
Understanding of nucleic acid therapeutics and diagnostics applications
Ability to work efficiently in a fast-paced, collaborative research environment
Strong organizational skills and attention to detail
Excellent written and verbal communication skills in English

Additional Information

The typical pay range for this role is:

Minimum: $93,750

Maximum: $156,250

This range represents the low and high end of the anticipated salary range for the California -based position. The actual base salary will depend on several factors such as: experience, skills, and location.

ABOUT LGC:

LGC is a leading, global life science tools company, providing mission-critical components and solutions into high-growth application areas across the human healthcare and applied market segments. Its high-quality product portfolio is comprised of mission-critical tools for genomic analysis and for quality assurance applications, which are typically embedded and recurring within our customers’ products and workflows and are valued for their performance, quality, and range.

OUR VALUES

PASSION
CURIOSITY
INTEGRITY
BRILLIANCE
RESPECT

EQUAL OPPORTUNITIES

LGC strongly believes that every job applicant and employee should be valued for their individual talents regardless of age, disability, race, color, ethnic or national origin, sex, sexual orientation, gender reassignment, marital or civil partnership, pregnancy or maternity, religion, or belief. Short listing, interviewing and selection will always be carried out without regard to gender, sexual orientation, marital status, color, race, nationality, ethnic or national origins, religion or belief, age, or trade union membership.

For more information about LGC, please visit our website www.lgcgroup.com

#scienceforasaferworld

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Refine Your Search

senior scientist, oligonucleotide chemist jobs in novato, ca

Senior Scientist, Oligonucleotide Chemist

Senior Hazards/Hazardous Materials Analyst

Senior Research Associate, Lipid Nanoparticle Formulation

Senior Scientist, Process Chemistry

Sr Scientist/Principal Scientist, Discovery Oncology (in vivo Biology)

Senior Scientist I/II, Analytical Chemistry

(Senior) Scientist, Stem Cell

Senior Algorithm Scientist

Principal Chemist

Senior Research Scientist

Senior Data Scientist

Forensic Computer Analyst SR

Senior Scientist, Antibody Discovery

(Senior) Research Associate, Stem Cell Biology

Scientist/Senior Scientist, Stem Cell/iPSC Research–Foster City, CA (San Francisco Bay Area)

Scientist II/Senior Scientist, Computational Chemistry, Drug Discovery

Senior Clinical Scientist, ECD

Senior Field Scientist

Senior Research Scientist

Decision Scientist Senior

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