Top 45 Senior program manager Jobs in St. Louis Mo

Senior Manager, R&D Portfolio Program Management
Bausch + Lomb —St. Louis, MO
- Surgery
- Computer literacy
- Bachelor of Science
- Paid holidays
- Disability insurance
Senior Program Manager
Cushman & Wakefield —St. Louis, MO
- $136,000 - $160,000 a year
- Full-time
- 5 years
- Bachelor's degree
- Conflict management
- Health savings account
- Disability insurance
Quick Apply
5d
Senior Program Manager
CACI —St. Louis, MO
- $82,100 - $172,400 a year
- Full-time
- Office
- 8 years
- Business development
- Health insurance
Senior Program Leader, Firm Planning
Edward Jones —St. Louis, MO
- $144,000 - $245,100 a year
- Full-time
- Hybrid work
- Office
- Microsoft Office
- Bachelor's degree
- Profit sharing
- Health savings account
5d
Sr. Manager Client Services
Advantage Solutions —St. Louis, MO
- $77,500 - $100,800 a year
- Full-time
- Microsoft Outlook
- Research
- Mid-level
- Health insurance
- Dental insurance
3d
Senior Product Leader - Program Management
U.S. Bank National Association —St. Louis, MO
- $149,515 - $175,900 a year
- Full-time
- Research
- Office
- Product management
- Paid holidays
- Disability insurance
Senior Director, Data Governance
Cushman & Wakefield —Creve Coeur, MO
- $178,500 - $210,000 a year
- Full-time
- Bachelor's degree
- Experience equivalent to degree accepted
- Senior level
- Health savings account
- Disability insurance
Quick Apply
Senior Program Planner - Strategy & Programs
Washington University in St. Louis —St. Louis, MO
- $84,200 - $148,500 a year
- Online Application
- Writing skills
- Pass drug screening
- Office
- Commuter assistance
- Employee assistance program
Senior Residency/Fellowship Program Coordinator - Neurosurgery
Washington University in St. Louis —St. Louis, MO
- $49,700 - $82,100 a year
- Full-time
- Word processing
- Computer literacy
- Office
- Commuter assistance
- Health savings account
Quick Apply
2d
Senior Manager, Infrastructure Protection Operations
Focus Financial Partners —St. Louis, MO
- $120,000 - $150,000 a year
- Remote
- Computer science
- 7 years
- Computer Science
- Health insurance
- Dental insurance
Senior Consultant
Edward Jones —St. Louis, MO
- $120,000 - $204,300 a year
- Full-time
- Hybrid work
- 7 years
- Office
- Analysis skills
- Profit sharing
- Health savings account
Manager Program Sr
FlightSafety International —Hazelwood, MO
- Microsoft Excel
- Microsoft Outlook
- Management
Senior Specialist, Benefits
Build-A-Bear Workshop, Inc. —St. Louis, MO
- Hybrid work
- Mid-level
- Office
- Analysis skills
- Retirement plan
Senior Director, Vendor Management
ADB Companies Inc —St. Louis, MO
- Microsoft Excel
- Pass drug screening
- 8 years
Quick Apply
4d
Senior Research Program Manager (Hybrid) - Emergency Medicine
Washington University in St. Louis —St. Louis, MO
- $77,700 - $120,400 a year
- Weekends as needed
- Hybrid work
- Pass drug screening
- English
- Office
- Commuter assistance
- Employee assistance program
Test Program Integrator - Technical Project Manager (Experienced & Senior)
Boeing —Berkeley, MO
- $103,700 - $171,350 a year
- Computer Science
- 5 years
- Bachelor of Science
- Health savings account
- Disability insurance
Life Enrichment Director
Clarendale Clayton —Clayton, MO
- $70,000 a year
- Full-time
- Mid-level
- 3 years
- Supervising experience
- Wellness program
- Health insurance
11d
Transformation Excellence Senior Manager, IAAD
Accenture —St. Louis, MO
- $122,700 - $317,200 a year
- Full-time
- Azure
- Sales
- AWS
- Paid holidays
- Disability insurance
Senior Project Manager
Curium Pharma —St. Louis, MO
- Weekends as needed
- Microsoft Word
- Microsoft Excel
- 5 years
Business Operations & Program Management Analyst (Senior) Job #807
Allen Integrated Solutions —St. Louis, MO
- Office
- 8 years
- Bachelor's degree
Quick Apply

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Senior Manager, R&D Portfolio Program Management

Bausch + Lomb -
St. Louis, MO

Apply Now

Job Details

Benefits

Paid holidays
Disability insurance
Health insurance
Dental insurance
Tuition reimbursement
Vision insurance
401(k) matching
Life insurance

Qualifications

Computer operation
Computer literacy
Pharmaceutical company experience
Project management experience in healthcare
Presentation creation
Managing projects
Productivity software
Research and development project management
Research & development
Manufacturing company experience

Full Job Description

Date: Aug 14, 2026

Location: US-MO-Saint Louis Kirkwood, US

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Company: Bausch+Lomb Companies Inc.

Bausch + Lomb (NYSE/TSX: BLCO) is a leading global eye health company dedicated to protecting and enhancing the gift of sight for millions of people around the world—from the moment of birth through every phase of life. Our mission is simple, yet powerful: helping you see better, to live better.

Our comprehensive portfolio of over 400 products is fully integrated and built to serve our customers across the full spectrum of their eye health needs throughout their lives. Our iconic brand is built on the deep trust and loyalty of our customers established over our 170-year history. We have a significant global research, development, manufacturing and commercial footprint of approximately 13,000 employees and a presence in approximately 100 countries, extending our reach to billions of potential customers across the globe. We have long been associated with many of the most significant advances in eye health, and we believe we are well positioned to continue leading the advancement of eye health in the future.

Objective:
The Senior Project Manager is a member of the R&D Global Portfolio and Project Management (GPPM) team, responsible for providing business and technical leadership for projects and programs within a designated Bausch + Lomb business vertical (e.g., Vision Care, Surgical, or Pharmaceuticals/Consumer).

The Senior Project Manager is accountable for ensuring that their assigned projects and programs are supported by a comprehensive global project strategy. This includes translating customer needs into product requirements, developing project valuations, planning for global registration and launch, and defining project scope, budget, resources, timelines, risk management strategies, and communication plans.

Beyond project oversight, the Senior Project Manager may also mentor GPPM staff and may support strategic initiatives or special projects across the broader R&D organization.

Responsibilities:
Program & Portfolio Leadership

Lead cross-functional teams to develop and execute global product development strategies, including:
Project scope and timelines
Target Product Profile (TPP) and value drivers
Financial modeling and risk analysis
Regulatory strategy and launch planning
Intellectual property (IP) strategy and functional execution
Navigate complexity and uncertainty using critical analysis and scenario planning.

Resource & Risk Management

Develop and maintain resource plans; resolve conflicts to maintain project schedule commitments.
Guide teams in proactive risk identification, mitigation, and contingency planning.
Communicate project interdependencies, risks, and issues clearly and effectively.

Cross-Functional Collaboration & Communication

Partner with Commercial, Operations, and R&D to ensure full support for projects and programs.[BD3.1]
Structure and motivate team to ensure efficient and successful execution.
Provide performance feedback to team members and functional managers.
Act as a central communication hub for project plans, status updates, and escalations.
Maintain accurate data in GPPM systems and deliver timely reports to support decision-making.

Governance & Compliance

Prepare and present Business Gate Reviews to ensure alignment and approval of project progression.
Ensure compliance with SOPs, GMPs, design control, EHS standards, and regulatory requirements.
Conduct lessons learned and implement best practices across teams.

Budget Management & Innovation

Coordinate project/program budgeting with supporting functions and ensure financial discipline.
May support business development activities, including due diligence and strategic partnerships.

Other duties as assigned.

Qualifications:
Education:

BS/BA in Science or Engineering. Advanced degree in science, engineering or business preferred.

Experience:

10+ years of Medical Device/Pharma industry experience and approximately 3-5 years of experience in R&D Project Management.

Special Skills:
Strong communication, organization, and presentation skills required.
Computer Literacy with skills in MS Excel, Word, Project, and PowerPoint.

Specialized Training:
MS Project (or equivalent) preferred
Project Management Professional (PMP) certification a plus
Agile Methodologies preferred for software projects.

Process Improvement:
Proven expertise in designing, implementing, and monitoring process improvement initiatives.

Systems Thinking & Operational Efficiency:
Experience defining and implementing policies, procedures, and systems to drive organizational effectiveness and sustainability.

Performance Under Pressure:
Highly effective at managing multiple competing priorities and deadlines, while maintaining positive, collaborative relationships.

Leadership & Influence:
Strong interpersonal skills, including active listening, emotional intelligence, and strong negotiation and influencing skills across all organizational levels, both internally and externally.
Skilled in leading through complex organizational dynamics, with the ability to influence, inspire, and achieve results through others.

Motivation & Team Enablement:
Demonstrates high energy and a results-driven mindset, consistently motivating teams to enable performance at all levels.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status.

U.S. based employees may be eligible for short-term and/or long-term incentives. They may also be eligible to participate in medical, dental, vision insurance, disability and life insurance, a 401(k) plan and company match, a tuition reimbursement program (select degrees), company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive sick time, floating holidays and paid vacation.

Job Applicants should be aware of job offer scams perpetrated through the use of the Internet and social media platforms.

To learn more please read Bausch + Lomb's Job Offer Fraud Statement.

Our Benefit Programs: Employee Benefits: Bausch + Lomb

Applicants must be authorized to work for ANY employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.

Apply Now

Refine Your Search

senior program manager jobs in st. louis mo

Senior Manager, R&D Portfolio Program Management

Senior Program Manager

Senior Program Manager

Senior Program Leader, Firm Planning

Sr. Manager Client Services

Senior Product Leader - Program Management

Senior Director, Data Governance

Senior Program Planner - Strategy & Programs

Senior Residency/Fellowship Program Coordinator - Neurosurgery

Senior Manager, Infrastructure Protection Operations

Senior Consultant

Manager Program Sr

Senior Specialist, Benefits

Senior Director, Vendor Management

Senior Research Program Manager (Hybrid) - Emergency Medicine

Test Program Integrator - Technical Project Manager (Experienced & Senior)

Life Enrichment Director

Transformation Excellence Senior Manager, IAAD

Senior Project Manager

Business Operations & Program Management Analyst (Senior) Job #807

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