Top 427 Cell platform lead Jobs in San Francisco, Ca

Senior Scientist/Principal Scientist, Regulatory T-cell Immunology
Sift Biosciences —San Carlos, CA
- $130,000 - $160,000 a year
- Full-time
- 5 years
- Master's degree
- Bachelor's degree
- Commuter assistance
- Health insurance
Quick Apply
2d
Cell Platform Lead
Foundry Robotics —San Francisco, CA
- $150,000 - $250,000 a year
- Full-time
- 8 years
- Senior level
- Leadership
- Health insurance
- Dental insurance
Quick Apply
5d
Director, Global Manufacturing Execution System Lead
Gilead Sciences —Foster City, CA
- $210,375 - $272,250 a year
- Full-time
- Engineering
- ERP systems
- 11+ years
- Health insurance
- Dental insurance
Senior Workday Platform Engineer
Natera —San Carlos, CA
- $128,800 - $161,050 a year
- HIPAA
- 8 years
- Senior level
- Commuter assistance
- Health insurance
Product Manager
University of California San Francisco —San Francisco, CA
- Full-time
- Mid-level
- AWS
- Bachelor's degree
Principal Scientist (Cell Line Development)
Exelixis, Inc. —Alameda, CA
- $150,000 - $213,000 a year
- Email
- 5 years
- Master's degree
- Bachelor's degree
- Paid holidays
- Disability insurance
Cell Therapy Specialist II
Arsenal Biosciences —San Francisco, CA
- $84,900 - $104,000 a year
- On call
- Mid-level
- Office
- Bachelor's degree
- Health savings account
- Health insurance
14d
Analytics Lead, Total Rewards
Crusoe —San Francisco, CA
- $120,000 - $175,000 a year
- Full-time
- SQL
- Analysis skills
- APIs
- Commuter assistance
- Paid parental leave
Quick Apply
Product Designer
Whatnot —San Francisco, CA
- $153,000 - $235,000 a year
- Full-time
- Remote
- 5 years
- Mentoring
- Senior level
- Paid parental leave
- Health insurance
Sr Prod Spec Cell Therapy Cell Culture - Berkeley, CA
Bayer —Berkeley, CA
- $93,840 - $140,760 a year
- Weekends as needed
- 5 years
- Doctor of Philosophy
- Training & development
- Health insurance
- Dental insurance
Program Manager
University of California San Francisco —San Francisco, CA
- Full-time
- Surgery
- Writing skills
- Research
8d
Senior Principal Scientist: Metabolomics/Cell Therapy Media Development
Genentech —San Francisco, CA
- $143,290 - $266,110 a year
- Online Application
- 5 years
- Doctor of Philosophy
- Mentoring
Manager, Web Platforms and Digital Experience
University of California San Francisco —San Francisco, CA
- Full-time
- Computer Science
- Master's degree
- Analysis skills
Research Program Manager
University of California San Francisco —San Francisco, CA
- Full-time
- Medicine
- Surgery
- Research
Senior Manager - AI Delivery Lead
Sia —San Francisco, CA
- $180,000 - $210,000 a year
- Full-time
- Hybrid work
- 5 years
- Office
- Master's degree
- Paid parental leave
- Health savings account
Quick Apply
Principal Scientist, Inflammation
Amgen —South San Francisco, CA
- $153,524.45 - $207,709.55 a year
- Bachelor's degree
- Doctor of Philosophy
- In-person
- Disability insurance
- Health insurance
12d
Senior Public Information Representative – Cancer
University of California San Francisco —San Francisco, CA
- $135,000 - $150,000 a year
- On call
- 7 years
- Master's degree
- Project management
Senior Manager of Openings & Operations
MINA Group —San Francisco, CA
- $110,000 - $125,000 a year
- Extended hours
- Microsoft Outlook
- 5 years
- Bachelor's degree
- Commuter assistance
- Health insurance
Quick Apply
Clinical Research Coordinator
University of California San Francisco —San Francisco, CA
- Writing skills
- HIPAA
- High school diploma or GED
Manager, Data Science
Whatnot —San Francisco, CA
- $221,000 - $320,000 a year
- Full-time
- Remote
- Analysis skills
- Senior level
- Leadership
- Paid parental leave
- Health insurance

I want to receive the latest job alert for cell platform lead in san francisco, ca

By signing in to your account, you agree to SimplyHired's Terms of Service and consent to our Cookie and Privacy Policy.

Explore jobs in more locations

cell platform lead jobs near san francisco, ca

Senior Principal Scientist jobs in San Francisco, CA

Program Manager jobs in San Francisco, CA

Platform Engineer jobs in San Francisco, CA

Senior Sales Specialist jobs in San Francisco, CA

Product Designer jobs in San Francisco, CA

Platform Manager jobs in San Francisco, CA

Principal Scientist jobs in South San Francisco, CA

Product Manager jobs in San Francisco, CA

Clinical Research Coordinator jobs in San Francisco, CA

Data Science Manager jobs in San Francisco, CA

Cell Culture Technician jobs in Berkeley, CA

Delivery Manager jobs in San Francisco, CA

Senior Operations Manager jobs in San Francisco, CA

Medical Laboratory Scientist jobs in Connecticut

Principal Scientist jobs in Florida

Assistant Principal School jobs in Denver, CO

Principal Scientist jobs in Watertown, MA

School Assistant Principal jobs in Dallas, TX

Principal Scientist jobs in Utah

Principal Scientist jobs in New York, NY

Senior Scientist/Principal Scientist, Regulatory T-cell Immunology

Sift Biosciences
San Carlos, CA

Quick Apply

Job Details

Full-time
$130,000 - $160,000 a year
2 days ago

Benefits

Commuter assistance
Health insurance
Dental insurance
401(k)
Paid time off
Parental leave
Vision insurance
Flexible schedule

Qualifications

Advanced cell culture techniques
Assay development
Cell Biology
Master's degree
Bachelor's degree
Doctor of Philosophy
Immunology
Managing projects
Pre-clinical studies in drug product development
Oncology

Full Job Description

Senior Scientist/Principal Scientist, Regulatory T-cell Immunology

Sift Bio is building a cutting-edge proprietary platform that combines AI, metagenomics, and high-throughput T-cell screening to discover epitopes that drastically amplify pre-existing immune memory responses, unlocking targeted, effective, and safe treatment for cancers and autoimmune diseases where current therapies fall short. Spinning out of UC Berkeley, the Sift Bio team brings together AI-driven discovery and deep translational immunology, with a proven track record of advancing novel immunotherapies from early concept through IND-enabling development. Collectively, the team has built and scaled high-throughput discovery platforms and led T-cell, peptide, and cell-based immunotherapy programs across leading academic labs, biotech startups, and biopharma. Merging this experience with proprietary datasets and computational pipelines, Sift Bio is shaping a new frontier in immunotherapy, unlocking the power of pre-existing immunity to create a fundamentally new class of treatments for immune dysfunctions. Our ultimate goal is to bring durable disease control to every patient.

We are seeking a Principal Scientist / Senior Scientist, Regulatory T-Cell Immunology to lead preclinical drug discovery, focusing on exploiting immunosuppressive T-cells to treat autoimmune diseases, cancer, and inflammation. This role will design and direct experiments, engineer novel cell therapies, and guide research strategy, manage project timelines, and collaborate with teams across clinical development, pharmacology, and regulatory affairs. This role will report to CTO and be fully onsite at 733 Industrial Road, San Carlos, CA.

KEY RESPONSIBILITIES:

Build, qualify, troubleshoot, and optimize end-to-end Treg suppression assays, including selection of potency readouts such as proliferation, cytokine production, activation markers, and other functional measures.
Create ex vivo assays that measure how antigen-specific T-cells drive suppression, benchmark findings against competing modalities, and diagnose underperforming Treg expansion programs through rigorous experimental design.
Characterize candidate epitopes using standard cellular, molecular, genetic, and immunological approaches, including antigen-specific Treg detection: tetramer/multimer staining and antigen-driven activation-induced marker (AIM) readouts, with matrix/pool deconvolution design for peptide screening.
Design and direct in vitro, ex vivo, and in vivo studies to evaluate mechanism of action, target biology, therapeutic efficacy, safety, persistence, stability, and suppressive function of candidate epitopes.
Develop and implement multi-parameter flow cytometry panels, functional immune assays, lineage-stability readouts, and disease-relevant models to support target validation, lead selection, and translational decision-making.
Lead external collaborations, CRO studies, and academic partnerships as needed, ensuring scientific rigor, timeline adherence, and data quality.

REQUIRED EXPERIENCE:

PhD in Immunology, Cell Biology, or a related field, plus 5+ years of post-doctoral or industry experience. Alternatively, a Master’s degree with 8 to 10+ years of biotech experience. Job title will commensurate with experience.
Excited by and scientifically driven to overcome complex technical challenges that will contribute to safe treatment for cancers and autoimmune diseases.
Deep hands-on experience with primary human Tregs and peripheral blood mononuclear cells (PBMCs), including working knowledge of best methods for isolation, expansion, and activation of Tregs/PBMCs
Prior experience developing antigen-specific tolerance or Treg-based approaches, peptide, protein, or engineered cell therapy setting, spanning antigen selection through in vivo functional readouts
Strong T-cell biology expertise, with extensive experience characterizing low frequency (<0.1%) CD8 and CD4 responses, and knowledge of how to improve readouts of rare T-cell responses
Knowledge of how to qualify Treg-based assays with known controls, for how to “rank” performance of manipulations -> impact Treg biology, and methods for how to overcome limitations of characterizing rare T-cell populations
Proven ability to contribute to the scientific direction of a project.
Strong written and oral communication skills for technical and non-technical audiences.
Conscientious team member with experience taking and giving constructive feedback.
Must be comfortable with executing lab work full time in a preclinical-stage startup environment, and capable of finding solutions to tough problems with limited resources.

PREFERRED QUALIFICATIONS:

Familiarity with HLA-transgenic mouse models and/or human PBMC xenograft/humanized models, and a clear-eyed view of which models are best suited to readout effects of an antigen-directed tolerance approach
Experience building immunotherapies for oncology or autoimmune disease settings

Sift Bio is pleased to offer competitive:

Medical, Dental, and Vision health plans.
Flexible time off.
Bonus and Equity plans.
Commuter transit benefit.
401(k) retirement plan.

Sift Bio is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind as outlined by applicable laws.

Pay: $130,000.00 - $160,000.00 per year

Benefits:

401(k)
Dental insurance
Flexible schedule
Health insurance
Paid time off
Parental leave
Vision insurance

Application Question(s):

How many years of industry or post-doc experience do you have?
Please tell us about your experience with preclinical drug discovery, focusing on exploiting immunosuppressive T-cells ideally to treat autoimmune diseases, cancer, and inflammation.

Education:

Bachelor's (Required)

Location:

San Carlos, CA 94070 (Preferred)

Ability to Relocate:

San Carlos, CA 94070: Relocate before starting work (Required)

Work Location: In person

Quick Apply

Refine Your Search

cell platform lead jobs in san francisco, ca

Senior Scientist/Principal Scientist, Regulatory T-cell Immunology

Cell Platform Lead

Director, Global Manufacturing Execution System Lead

Senior Workday Platform Engineer

Product Manager

Principal Scientist (Cell Line Development)

Cell Therapy Specialist II

Analytics Lead, Total Rewards

Product Designer

Sr Prod Spec Cell Therapy Cell Culture - Berkeley, CA

Program Manager

Senior Principal Scientist: Metabolomics/Cell Therapy Media Development

Manager, Web Platforms and Digital Experience

Research Program Manager

Senior Manager - AI Delivery Lead

Principal Scientist, Inflammation

Senior Public Information Representative – Cancer

Senior Manager of Openings & Operations

Clinical Research Coordinator

Manager, Data Science

I want to receive the latest job alert for cell platform lead in san francisco, ca

Related Searches

Explore jobs in more locations

Job Seeker Tools

Employer Tools

Browse

Stay Connected